Use of botulinum neurotoxin A in uncontrolled salivation in children with cerebral palsy: a pilot study

2012 ◽  
Vol 41 (12) ◽  
pp. 1540-1545 ◽  
Author(s):  
J. Tiigimäe-Saar ◽  
E. Leibur ◽  
A. Kolk ◽  
I. Talvik ◽  
T. Tamme
Keyword(s):  
Cerebral Palsy ◽  
Pilot Study ◽  
Botulinum Neurotoxin ◽  
Botulinum Neurotoxin A ◽  
Children With Cerebral Palsy

Functional outcomes of botulinum neurotoxin-A injection followed by reciprocal electrical stimulation in children with cerebral palsy: A randomized controlled trial

2020 ◽  
pp. 1-11
Author(s):  
Ragab K. Elnaggar ◽  
Bader A. Alqahtani ◽  
Mohammed F. Elbanna
Keyword(s):  
Cerebral Palsy ◽  
Electrical Stimulation ◽  
Botulinum Neurotoxin ◽  
Hand Function ◽  
Botulinum Neurotoxin A ◽  
Group Iii ◽  
Children With Cerebral Palsy ◽  
Spastic Hemiplegia ◽  
Upper Extremity Function

Background: The integration of therapeutic approaches is increasingly recommended for children with cerebral palsy, to enhance outcomes. Nevertheless, clinicians still opt for separate or combined therapies based on little credible knowledge. Objective: This study endeavored to evaluate the effect of botulinum neurotoxin-A (BoNT-A) injection and reciprocal neuromuscular electrical stimulation (rNMES) and their combination on the upper extremity function in children with spastic hemiplegia. Methods: Sixty-four children with spastic hemiplegia (aged 6– 10 years) were randomly assigned to four treatment-based groups [group I (BoNT-A), group II (rNMES), group III (combined BoNT-A and rNMES), and group IV (Control)]. All children received a physical rehabilitation program, thrice/week over three months. Unilateral upper-limb function, bimanual hand function, and real-time arm-hand function were assessed using Melbourne Assessment (MA), Assisting Hand Assessment (AHA), and Pediatric Motor Activity Log (PMAL) scales respectively pre-treatment, post-treatment, and at 6 months follow-up. Results: Post-treatment, group III achieved greater improvement in MA, AHA, and PMAL compared to other groups (all P <  0.05), and the difference remained in favor of group III at the follow-up (all P <  0.05). Conclusions: This study suggests that BoNT-A and rNMES combined are more effective than either of them alone to enhance upper-extremity function in children with spastic hemiplegia.

scholarly journals Systemic adverse events after botulinum neurotoxin A injections in children with cerebral palsy

2018 ◽  
Vol 60 (11) ◽  
pp. 1172-1177 ◽  
Author(s):  
Simon P Paget ◽  
Caitlyn M Swinney ◽  
Karen L O Burton ◽  
Karen Bau ◽  
Stephen J O'Flaherty
Keyword(s):  
Cerebral Palsy ◽  
Adverse Events ◽  
Botulinum Neurotoxin ◽  
Botulinum Neurotoxin A ◽  
Children With Cerebral Palsy

scholarly journals Joint and Muscle Assessments of the Separate Effects of Botulinum NeuroToxin-A and Lower-Leg Casting in Children With Cerebral Palsy

2020 ◽  
Vol 11 ◽  
Author(s):  
Nicky Peeters ◽  
Anja Van Campenhout ◽  
Britta Hanssen ◽  
Francesco Cenni ◽  
Simon-Henri Schless ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Botulinum Neurotoxin ◽  
Lower Leg ◽  
Botulinum Neurotoxin A ◽  
Children With Cerebral Palsy

scholarly journals Submandibular duct ligation after botulinum neurotoxin A treatment of drooling in children with cerebral palsy

2020 ◽  
Vol 62 (7) ◽  
pp. 861-867 ◽  
Author(s):  
Stijn Bekkers ◽  
Ineke M J Pruijn ◽  
Karen Van Hulst ◽  
Corinne P Delsing ◽  
Corrie E Erasmus ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Botulinum Neurotoxin ◽  
Botulinum Neurotoxin A ◽  
Submandibular Duct ◽  
Duct Ligation ◽  
Children With Cerebral Palsy
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