Response to Stoelinga's commentary regarding systematic review on the recurrence rate of keratocystic odontogenic tumour in relation to treatment modalities

2012 ◽  
Vol 41 (12) ◽  
pp. 1586-1587
Author(s):  
T. Kaczmarzyk ◽  
I. Mojsa ◽  
J. Stypulkowska
Keyword(s):  
Systematic Review ◽  
Recurrence Rate ◽  
Treatment Modalities ◽  
Odontogenic Tumour ◽  
Keratocystic Odontogenic Tumour

scholarly journals Keratocystic Odontogenic Tumour with Extraosseal Spread: Evaluation of the Effect Carnoy’s Solution

2015 ◽  
Vol 116 (4) ◽  
pp. 303-313 ◽  
Author(s):  
Jitka Levorová ◽  
Vladimír Machoň ◽  
Pavel Grill ◽  
Dušan Hirjak ◽  
René Foltán
Keyword(s):  
High Risk ◽  
Recurrence Rate ◽  
Soft Tissues ◽  
Inclusion Criteria ◽  
Odontogenic Tumour ◽  
Risk Of Recurrence ◽  
Carnoy’S Solution ◽  
Patient Groups ◽  
Keratocystic Odontogenic Tumour ◽  
Rare Benign Tumour

Keratocystic odontogenic tumour is relatively rare benign tumour. It is characterized by its fast aggressive growth and high risk of recurrence. Treatment is always surgical: conservative (enucleation, marsupialization) or aggressive (enucleation followed by application of Carnoy’s solution, cryotherapy; peripheral ostectomy or en block resection of the jaw). Authors analysed retrospectively 22 patients who fulfilled inclusion criteria, i.e. had odontogenic keratocystic tumour of mandible, wherein antero-posterior dimension was at least 30 mm, and the tumour penetrated into the surrounding soft tissues. All patients underwent tumour enucleation, in 11 patients Carnoy’s solution was given into the bone cavity after enucleation. The recurrence rate in the evaluation at least 36 months after surgery was both patient groups the same: 45.4%.

scholarly journals Keratocystic odontogenic tumour: An experience in the northeast of Brazil

2011 ◽  
Vol 139 (5-6) ◽  
pp. 291-297 ◽  
Author(s):  
Mello Araújo ◽  
Gurgel Araújo ◽  
Gonçalves Ramos ◽  
Souza de ◽  
Brandi Schlaepfer-Sales ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Recurrence Rate ◽  
Basal Cell ◽  
Radiographic Finding ◽  
Brazilian Population ◽  
Anatomical Location ◽  
Odontogenic Tumour ◽  
Odontogenic Tumours ◽  
Keratocystic Odontogenic Tumour

Introduction. Keratocystic odontogenic tumours raise particular interest, because of their high recurrence rate and association with nevoid basal cell carcinoma syndrome. Objective. To analyze the clinical and histopathological features of all cases diagnosed as keratocystic odontogenic tumour in a Brazilian population. Methods. A total of 64 keratocystic odontogenic tumours, arising in forty-six patients, were evaluated using the following parameters: association with nevoid basal cell carcinoma syndrome, gender, age at first diagnosis, race, anatomical location, symptoms, radiographic features, history of recurrence, association with teeth, and treatment. Results. Keratocystic odontogenic tumours were more frequent among women than men (1:0.84). The mean patient age was 31.5 years (SD: ?16.6). Ten tumours (16.4%) involved the maxilla and 51 (83.6%) the mandible. Swelling (n=12; 46.1%), followed by pain and swelling (n=4; 15.3%), were most common clinical manifestations. A unilocular radiotransparency with well-defined margins was the main radiographic finding (n=29; 87.8%). A significant association was observed between the multilocular radiographic pattern and recurrence (p<0.05, Fisher?s Test). Sixty-one (95.3%) tumours were treated by surgical enucleation followed by bone curettage, and the recurrence rate was 13% (n=6). This study showed that the keratocystic odontogenic tumours relapsed within a mean period of 25-36 months. Conclusion. Despite the results of this study being similar to previous reports found in the literature, it provides an important insight about keratocystic odontogenic tumours in a Brazilian population.

scholarly journals Central Odontogenic Fibroma: characteristics and management

2021 ◽  
Vol 27 (2) ◽  
pp. 25
Author(s):  
Sabrina Bennabi ◽  
Philippe Lesclous ◽  
Alexandra Cloitre
Keyword(s):  
Systematic Review ◽  
Malignant Transformation ◽  
Recurrence Rate ◽  
Recent Change ◽  
Review Of The Literature ◽  
Odontogenic Tumour ◽  
Odontogenic Fibroma ◽  
Central Odontogenic Fibroma

Introduction: Central Odontogenic Fibroma (COF) is a rare benign odontogenic tumour of the jaws. Until its recent change in classification by the WHO in 2017, this entity has gone without an agreed upon definition for many years. For this reason, COF would remain largely unknown to practitioners. Corpus: The pedagogical objectives of this article are, through a systematic review of the literature using the PRISMA methodology, to list the epidemiological, aetiological, clinical, radiological, histological, therapeutic and prognostic characteristics of COF. All the data collected made it possible to establish a COF management summary for practitioners in order to optimize it. Conclusion: Based on the 135 cases listed, it appears that surgical enucleation is the treatment of choice for COF. The recurrence rate is low and malignant transformation has never been reported. However, regular clinical and radiological follow-up of patients over several years seems to be a justified precaution.

scholarly journals Treatment Algorithm for Ameloblastoma

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Madhumati Singh ◽  
Anjan Shah ◽  
Auric Bhattacharya ◽  
Ragesh Raman ◽  
Narahari Ranganatha ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Treatment Algorithm ◽  
Radical Resection ◽  
Malignant Potential ◽  
Treatment Modalities ◽  
High Recurrence Rate ◽  
Anatomical Location ◽  
Odontogenic Tumour ◽  
Treatment Algorithms ◽  
Fibula Graft

Ameloblastoma is the second most common benign odontogenic tumour (Shafer et al. 2006) which constitutes 1–3% of all cysts and tumours of jaw, with locally aggressive behaviour, high recurrence rate, and a malignant potential (Chaine et al. 2009). Various treatment algorithms for ameloblastoma have been reported; however, a universally accepted approach remains unsettled and controversial (Chaine et al. 2009). The treatment algorithm to be chosen depends on size (Escande et al. 2009 and Sampson and Pogrel 1999), anatomical location (Feinberg and Steinberg 1996), histologic variant (Philipsen and Reichart 1998), and anatomical involvement (Jackson et al. 1996). In this paper various such treatment modalities which include enucleation and peripheral osteotomy, partial maxillectomy, segmental resection and reconstruction done with fibula graft, and radical resection and reconstruction done with rib graft and their recurrence rate are reviewed with study of five cases.

Comparative Efficacy of Hidrocystoma Treatments: A Systematic Review

2020 ◽  
Vol 24 (5) ◽  
pp. 474-480
Author(s):  
Thomas Trischman ◽  
Jeffrey F. Scott
Keyword(s):  
Systematic Review ◽  
Recurrence Rate ◽  
Surgical Procedures ◽  
Overall Response Rate ◽  
Response Rate ◽  
Treatment Options ◽  
Treatment Modalities ◽  
Comparative Efficacy ◽  
Overall Response ◽  
Medical Therapies

Introduction Although various treatment options for hidrocystomas have been described, the comparative efficacy of these treatments is poorly understood. Methods We conducted a systematic review of all articles describing the treatment of hidrocystomas. Treatment modalities were categorized as destructive surgical procedures, skin-directed therapies, systemic medical therapies, general measures, or combined. Patient and tumor characteristics, as well as response rate, recurrence rate, and adverse effects, were extracted from each article. Results A total of 94 articles involving 192 patients and 255 unique treatment events were included in the final analysis. Destructive surgical procedures had an overall response rate and recurrence rate of 92.9% and 10.8%, respectively. Skin-directed therapies had an overall response rate of 72.6%. The overall response rate to systemic medical therapies was 71.4%. Solitary hidrocystomas were primarily treated with destructive surgical procedures, including excision, which was associated with a 4.7% recurrence rate. Multiple hidrocystomas were successfully treated with a variety of therapies, including destructive surgical procedures and skin-directed therapies requiring ongoing or repeated therapy. Conclusions Excision has the highest efficacy for solitary hidrocystomas. A number of therapies have shown efficacy for multiple hidrocystomas, including lasers, intracystic trichloroacetic acid, intracystic hypertonic glucose, topical and oral anticholinergics, and botulinum toxin. Aluminum chloride is associated with a low response rate. Larger comparative studies are needed to further evaluate the optimal treatments for solitary and multiple hidrocystomas.

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