Rapid simultaneous spectrophotometric determination of acetaminophen, phenylephrine, and guaifenesin in a cold syrup formulation based on continuous wavelet transform and first derivative transform methods

Optik ◽  
2021 ◽  
Vol 230 ◽  
pp. 166323
Author(s):  
Mahdi Ebrahimi ◽  
Mahmoud Reza Sohrabi ◽  
Fereshteh Motiee ◽  
Mehran Davallo
2008 ◽  
Vol 59 (5) ◽  
Author(s):  
Erdal Dinc ◽  
Dumitru Baleanu

Simultaneous spectrophotometric analysis of tablets and binary mixtures containing vitamin C (VC) and aspirin (ASP) with overlapping spectra was performed by ratio spectra-continuous wavelet transform (RS-CWT) and ratio spectra-derivative spectrophotometry (RS-DS). In the application of RS-CWT and RS-DS to the simultaneous analysis of VC and ASP no separation step was considered. The basis of RS-CWT and RS-DS approaches is the transformation and the derivation of the ratio spectra of the related compounds and their samples. Calibration graphs in the linear concentration range 4-20 mg/mL for both compounds were obtained by measuring the CWT and first derivative amplitudes at 260.8 nm for VC and 234.6 nm for ASP in the BIOR-CWT spectra and at 256.0 nm for VC and 230.7 nm for ASP in the first derivative of ratio spectra, respectively. Both methods were tested by using the synthetic mixtures and standard addition technique, and were applied to the simultaneous determination of VC and ASP in commercial effervescent tablets and a good coincidence was reported for experimental results obtained by the proposed RS-CWT and RS-DS.


2018 ◽  
Vol 10 (22) ◽  
pp. 2588-2594
Author(s):  
Fathy M. Salama ◽  
Khalid A. Attia ◽  
Ahmed A. Abouserie ◽  
Ahmed El-Olemy ◽  
Ebrahim Abolmagd

Two methods have been developed and validated for simultaneous determination of amoxicillin sodium and diclofenac sodium in their pure and combined pharmaceutical dosage forms.


2012 ◽  
Vol 20 (13) ◽  
pp. 13878 ◽  
Author(s):  
M. Grabka ◽  
S. Pustelny ◽  
P. Mergo ◽  
W. Gawlik

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