Effect of high fat diets on the NTPDase, 5′‐nucleotidase and acetylcholinesterase activities in the central nervous system

2017 ◽  
Vol 64 (1) ◽  
pp. 54-58 ◽  
Author(s):  
Rosilene Rodrigues Kaizer ◽  
Rosélia Maria Spanevello ◽  
Eduarda Costa ◽  
Vera Maria Morsch ◽  
Maria Rosa Chitolina Schetinger
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
High Fat ◽  
High Fat Diets ◽  
The Central Nervous System ◽  
Fat Diets

High‐fat diets on the enteric nervous system: Possible interactions and mechanisms underlying dysmotility

2021 ◽  
Author(s):  
Patricia Pereira Almeida ◽  
Luisa Valdetaro ◽  
Beatriz Bastos de Moraes Thomasi ◽  
Milena Barcza Stockler‐Pinto ◽  
Ana Lúcia Tavares‐Gomes
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
High Fat ◽  
High Fat Diets ◽  
Fat Diets

A mechanism underlying mature-onset obesity: evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants

2004 ◽  
Vol 286 (6) ◽  
pp. R994-R1004 ◽  
Author(s):  
Edward A. Fox ◽  
Mardi S. Byerly
Keyword(s):  
Positive Feedback ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Meal Size ◽  
High Fat ◽  
Meal Pattern ◽  
Balanced Diet ◽  
High Fat Diets ◽  
The Central Nervous System ◽  
Fat Diets

Mice deficient in brain-derived neurotrophic factor (BDNF) develop mature-onset obesity, primarily due to overeating. To gain insight into the mechanism of this hyperphagia, we characterized food intake, body weight, meal pattern, and meal microstructure in young and mature mice fed balanced or high-fat diets. Hyperphagia and obesity occurred in mature but not young BDNF mutants fed a balanced diet. This hyperphagia was mediated by increased meal number, which was associated with normal meal size, meal duration, and satiety ratio. In contrast, the high-fat diet induced premature development of hyperphagia and obesity in young BDNF mutants and a similar magnitude hyperphagia in mature mutants. This hyperphagia was supported by increased meal size and was accompanied by a reduced satiety ratio. Thus the mechanism underlying hyperphagia was present before significant weight gain, but whether it occurred, and whether meal frequency or meal size was altered to support it, was modulated by a process associated with aging and by diet properties. Meal pattern changes associated with the balanced diet suggested meal initiation, and the oropharyngeal positive feedback that drives feeding, were enhanced and might have contributed to overeating in BDNF mutants, whereas negative feedback was normal. Consistent with this hypothesis, meal microstructure revealed that all hyperphagic mutant groups exhibited increased intake rates at meal onset. Therefore, the central nervous system targets of BDNF actions may include orosensory brain stem neurons that process and transmit positive feedback or forebrain neurons that modulate its strength.

scholarly journals High-fat diet feeding differentially affects the development of inflammation in the central nervous system

2016 ◽  
Vol 13 (1) ◽  
Author(s):  
Owein Guillemot-Legris ◽  
Julien Masquelier ◽  
Amandine Everard ◽  
Patrice D. Cani ◽  
Mireille Alhouayek ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
High Fat Diet ◽  
High Fat ◽  
The Central Nervous System

scholarly journals Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system

2014 ◽  
Vol 35 ◽  
pp. 33-42 ◽  
Author(s):  
Laura B. Buckman ◽  
Alyssa H. Hasty ◽  
David K. Flaherty ◽  
Christopher T. Buckman ◽  
Misty M. Thompson ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
High Fat Diet ◽  
Immune Cell ◽  
Cell Entry ◽  
High Fat ◽  
The Central Nervous System

Tibolone regulates systemic metabolism and the expression of sex hormone receptors in the central nervous system of ovariectomised rats fed with high-fat and high-fructose diet

2020 ◽  
Vol 1748 ◽  
pp. 147096 ◽  
Author(s):  
Angélica Coyoy-Salgado ◽  
Julia J. Segura-Uribe ◽  
Juan Manuel Gallardo ◽  
Norma A. Estrada-Cruz ◽  
Ignacio Camacho-Arroyo ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hormone Receptors ◽  
Sex Hormone ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose ◽  
The Central Nervous System ◽  
Ovariectomised Rats
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