Pattern of cerebral hypoperfusion in Alzheimer's disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: Initial experience

2006 ◽  
Vol 1290 ◽  
pp. 108-122 ◽  
Author(s):  
Nathan A. Johnson ◽  
Geon-Ho Jahng ◽  
Michael W. Weiner ◽  
Bruce L. Miller ◽  
Helena C. Chui ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Alba Sierra-Marcos

Alzheimer’s disease (AD) depicts dynamic changes in regional brain function from early stages of the disease. Arterial spin labeling- (ASL-) based MRI methods have been applied for detecting regional cerebral blood flow (rCBF) perfusion changes in patients with AD and mild cognitive impairment (MCI). Nevertheless, the results obtained from ASL studies in AD and MCI are still controversial, since rCBF maps may show both hypoperfusion or hyperperfusion areas in brain structures involved in different cognitive functions. The goal of this review is to provide the current state of the art regarding the role of ASL for detecting distinctive perfusion patterns in subjects with MCI and/or AD. The ability to obtain this information using a noninvasive and widely available modality such as ASL should greatly enhance the knowledge into the broad range of hemodynamically related changes taking place during the cognitive decline process in AD.


2004 ◽  
Vol 25 ◽  
pp. S273
Author(s):  
Nathan A. Johnson ◽  
Geon-Ho Jahng ◽  
Michael W. Weiner ◽  
Helena C. Chui ◽  
Bruce Miller ◽  
...  

2015 ◽  
Vol 26 (2) ◽  
pp. 207-212 ◽  
Author(s):  
Sebastien Verclytte ◽  
Renaud Lopes ◽  
Pierre Lenfant ◽  
Adeline Rollin ◽  
Franck Semah ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document