scholarly journals Therapeutics Role of Alpha-Lipoic Acid on Memory and Fronto-hippocampal Cortex of Scopolamine-Induced Memory Impaired Adult Male Wistar Rats

IBRO Reports ◽  
2019 ◽  
Vol 7 ◽  
pp. 7-8
Author(s):  
A.E. Memudu ◽  
R. Adanike
Keyword(s):  
Adult Male ◽  
Lipoic Acid ◽  
Wistar Rats ◽  
Alpha Lipoic Acid ◽  
Male Wistar Rats

Investigation of the role of α-lipoic acid on fatty acids profile, some minerals (zinc, copper, iron) and antioxidant activity against aluminum-induced oxidative stress in the liver of male rats

2017 ◽  
Vol 28 (4) ◽  
Author(s):  
Zafer Sahin ◽  
Ahmet Ozkaya ◽  
Okkes Yilmaz ◽  
Abdurrauf Yuce ◽  
Mehmet Gunes
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Antioxidant Activity ◽  
Lipoic Acid ◽  
Wistar Rats ◽  
Male Rats ◽  
Fatty Acids Profile ◽  
Male Wistar Rats ◽  
Aluminum Accumulation

AbstractBackground:We have investigated the effects of α-lipoic acid (LA), a powerful antioxidant, on the fatty acid (FA) profiles, aluminum accumulation, antioxidant activity and some minerals such as zinc, copper and iron against aluminum chloride (AlClMethods:Twenty-eight male Wistar rats were divided into four groups as control, LA, AlClResults:AlClConclusions:These results indicate that AlCl

Role of serotonin and serotonin receptors in the apomorphine-induced aggressive behaviour of adult male Wistar rats

2000 ◽  
Vol 10 ◽  
pp. 386
Author(s):  
V. Matto ◽  
T. Skrebuhhova-Malmros ◽  
R. Rudissaar ◽  
K. Pruus ◽  
L. Allikmets
Keyword(s):  
Adult Male ◽  
Serotonin Receptors ◽  
Aggressive Behaviour ◽  
Wistar Rats ◽  
Male Wistar Rats

scholarly journals Chronic exposure of adult male Wistar rats to bisphenol A causes testicular oxidative stress: Role of gallic acid

2020 ◽  
Vol 54 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Samuel Gbadebo Olukole ◽  
Eunice Olufunke Ola-Davies ◽  
Damilare Olaniyi Lanipekun ◽  
Bankole Olusiji Oke
Keyword(s):  
Oxidative Stress ◽  
Bisphenol A ◽  
Gallic Acid ◽  
Adult Male ◽  
Chronic Exposure ◽  
Wistar Rats ◽  
The Body ◽  
Male Rats ◽  
Male Wistar Rats

AbstractObjectives. Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well as testicular lesions in exposed animals. This work sought to study the role of gallic acid (GA), a known antioxidant, on the BPA-induced testicular oxidative stress in adult male Wistar rats using serum hormone analysis, histopathology, and biochemical assays.Methods. Adult male rats were divided into four groups (n=10) including control (0.2 ml of corn oil), GA (20 mg/kg/day), BPA (10 mg/kg/day), BPA+GA (BPA, 10 mg/kg/day + GA, 20 mg/kg/day). All medications were given by oral gavage for 45 consecutive days. The body and testicular weights were measured. Blood and organ samples were collected for the serum hormonal assay: testosterone (T), luteinizing hormone (LH), follicle stimulating hormone (FSH) and prolactin (PRL), and tissue biochemistry analysis: superoxide dismutase (SOD), reduced glutathione (GSH), glutathione-S-transferase (GST), malondialdehyde (MDA), hydrogen peroxide (H2O2), respectively.Results. The BPA-treated rats showed significant reduction in the gonadosomatic index. BPA also caused significant decrease in the levels of the serum testosterone and prolactin. Furthermore, BPA induced testicular oxidative stress by decreasing the activities of antioxidant enzymes and increasing reactive oxygen species. However, co-treatment with GA protected against these alterations.Conclusion. Findings from the present study confirmed the previously reported data and show that the ability of GA, as a potent antioxidant, may protect against BPA-induced alterations in the male reproductive function. Hence, GA protects against testicular oxidative stress in adult male Wistar rats following chronic exposure to BPA.

scholarly journals The role of oxidative stress and effect of alpha-lipoic acid in reexpansion pulmonary edema – an experimental study

2010 ◽  
Vol 6 ◽  
pp. 848-853 ◽  
Author(s):  
Seyfettin Gumus ◽  
Orhan Yucel ◽  
Mehmet Gamsizkan ◽  
Ayse Eken ◽  
Omer Deniz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Experimental Study ◽  
Pulmonary Edema ◽  
Lipoic Acid ◽  
Alpha Lipoic Acid ◽  
Reexpansion Pulmonary Edema

scholarly journals Anti‐Fertility Effects of Amlodipine in Adult Male Wistar Rats

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Adelaja Abdulazeez Akinlolu ◽  
Olaide Ghazali ◽  
Adebayo Kehinde Adefule
Keyword(s):  
Adult Male ◽  
Wistar Rats ◽  
Male Wistar Rats
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