scholarly journals Treatment of sickle cell crises

2020 ◽  
Vol 42 ◽  
pp. 8
Author(s):  
Salam Alkindi
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Crises

Increased Urinary Porphyrin Excretion in Sickle Cell Crises

1966 ◽  
Vol 123 (1) ◽  
pp. 1-4 ◽  
Author(s):  
H. N. Naumann ◽  
L. W. Diggs ◽  
F. S. Schlenker ◽  
L. Barreras
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Crises

Efficacy and Tolerance of Lidocaine 5% Patches in Neuropathic Pain and Pain Related to Vaso-occlusive Sickle Cell Crises in Children: A Prospective Multicenter Clinical Study

Pain Practice ◽  
2018 ◽  
Vol 18 (6) ◽  
pp. 788-797 ◽  
Author(s):  
Vanessa Rousseau ◽  
Magali Morelle ◽  
Céline Arriuberge ◽  
Sophie Darnis ◽  
Sylvie Chabaud ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Clinical Study ◽  
Sickle Cell ◽  
Sickle Cell Crises ◽  
Multicenter Clinical Study

A double-blind randomized trial of low-dose oral urea to prevent sickle cell crises

1982 ◽  
Vol 35 (2) ◽  
pp. 151-161 ◽  
Author(s):  
Mitchell Gail ◽  
Janis Beach ◽  
Allison Dark ◽  
Roger Lewis ◽  
Helga Morrow
Keyword(s):  
Randomized Trial ◽  
Sickle Cell ◽  
Low Dose ◽  
Double Blind ◽  
Dose Oral ◽  
Sickle Cell Crises

Fetal Addiction to Pentazocine

PEDIATRICS ◽  
1975 ◽  
Vol 55 (6) ◽  
pp. 888-889
Author(s):  
Arthur E. Kopelman
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Urinary Tract Infection ◽  
Case Report ◽  
Sickle Cell ◽  
Withdrawal Symptoms ◽  
Sickle Hemoglobin ◽  
Severe Withdrawal ◽  
Sickle Cell Crises ◽  
Neonatal Withdrawal

A case of neonatal withdrawal symptoms following maternal use of pentazocine was recently reported.1 This is the report of a second case with severe withdrawal symptoms which were successfully treated with phenobarbital. CASE REPORT A 2,180-gm, small-for-date, black female infant was delivered by cesarean section at 37 weeks' gestation. The mother, a 26-year-old gravida 3, para 0 woman with sickle cell anemia, had several painful sickle cell crises, congestive heart failure, pneumonia, and a urinary tract infection during this pregnancy. The two previous pregnancies had ended in abortion. In the second half of this pregnancy, she was treated with frequent packed-cell transfusions in order to decrease to less than 50% the number of her erythrocytes with sickle hemoglobin and hence the risk of clinical sickling.

Urinary creatine: biochemical indicator for evaluation of sickle cell crises.

1985 ◽  
Vol 31 (7) ◽  
pp. 1232-1234 ◽  
Author(s):  
C Beyer ◽  
L W Statius van Eps ◽  
J J Kastelein ◽  
D P Brandjes ◽  
W M Mairuhu ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
Sickle Cell ◽  
Excretion Rate ◽  
Serum Lactate ◽  
High Serum ◽  
Serum Lactate Dehydrogenase ◽  
Muscle Involvement ◽  
Biochemical Indicator ◽  
Excretion Rates ◽  
Sickle Cell Crises

Abstract In a patient with known sickle cell beta 0-thalassemia we measured serum lactate dehydrogenase (LD) activity and 24-h urinary creatine excretion rate as markers to evaluate sickle cell crises. We believe that a distinction based on biochemical findings can be made between hemolytic and painful vaso-occlusive sickle cell crises with muscular involvement. To assess hemolytic crises by objective biochemical measures, we have used assay of LD activity, and to assess painful crises with muscular involvement objectively, the 24-h urinary creatine excretion rate. We conclude that hemolytic crises are characterized by high serum LD activities. Furthermore, we conclude that--at least in this patient--painful crises are accompanied by high 24-h urinary creatine excretion rates. Our findings suggest that muscle involvement may play an important role in painful vaso-occlusive sickle cell crises.

Sickle cell crisis as evaluated from measurements of hydroxybutyrate dehydrogenase and myoglobin in plasma.

1981 ◽  
Vol 27 (2) ◽  
pp. 314-316 ◽  
Author(s):  
E F Roth ◽  
P A Bardfeld ◽  
S J Goldsmith ◽  
E Radel ◽  
J C Williams
Keyword(s):  
Steady State ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
High Specificity ◽  
Mean Value ◽  
Cell Disease ◽  
Sickle Cell Crisis ◽  
The Mean ◽  
Low Sensitivity ◽  
Sickle Cell Crises

Abstract Data on plasma hydroxybutyrate dehydrogenase activity (I) and myoglobin concentration were used to evaluate painful sickle cell crises. I was increased during non-crisis steady state in patients with sickle cell disease as compared to normal values (232, SD 79.7 vs 85, SD 33 Sigma units/mL). During crisis, the mean value for I increased further to 379 (SD 139) Sigma units/mL. For 12 patients evaluated both during steady state and crisis, there was a mean increase in plasma I of 131% (SD 76%). Repeated determinations of I in sickle cell disease patients during several months while they were in steady state showed that baseline I varied by no more than 20% from the mean. Plasma myoglobin in patients with sickle cell disease was not above normal, but during crisis 21 of 39 patients tested had increased plasma myoglobin concentrations. Our data suggest that I may be a useful indicator of sickle cell crisis when the patient's own baseline value is available for comparison. Plasma myoglobin measurements give evidence of muscle damage during crisis with high specificity but low sensitivity.

scholarly journals Red cells in sickle cell crisis: observations on the pathophysiology of crisis

Blood ◽  
1977 ◽  
Vol 49 (6) ◽  
pp. 967-979 ◽  
Author(s):  
EE Rieber ◽  
G Veliz ◽  
S Pollack
Keyword(s):  
Sickle Cell ◽  
Red Cells ◽  
Red Cell ◽  
Molecular Abnormality ◽  
Sickle Cell Crisis ◽  
Sickle Cell Crises

Abstract The pathophysiology of the occurrence and resolution of sickle cell crisis is unknown. The molecular abnormality is constant, while crisis is episodic. In the present study, red cell filterability and sickling with deoxygenation have been measured during sickle cell crises. Recovery from sickle crisis is associated with an increased filterability of the circulating red cell and a decreased susceptibility of the red cell to sickle with deoxygenation (p less than 0.05). The possibility that these changes are responsible for the resolution of crisis is suggested.

scholarly journals 1366 The Evolution of Pain During Hospitalization of Children with Painful Sickle Cell Crises

2010 ◽  
Vol 68 ◽  
pp. 676-677
Author(s):  
L Al Lawati ◽  
E Courtois ◽  
L Tostivint ◽  
E Lesprit ◽  
B Quinet ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Crises
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