scholarly journals Hematological parameters, serum iron and vitamin B 12 levels in hospitalized Palestinian adult patients infected with Helicobacter pylori : a case–control study

2018 ◽  
Vol 40 (2) ◽  
pp. 160-165 ◽  
Author(s):  
Saleh Nazmy Mwafy ◽  
Wesam Mohammad Afana
2011 ◽  
Vol 58 (4) ◽  
Author(s):  
Amanat Ali ◽  
Mostafa I Waly ◽  
Yahya M Al-Farsi ◽  
Musthafa M Essa ◽  
Marwan M Al-Sharbati ◽  
...  

High serum homocysteine (Hcy) level is regarded as an indicator for impairment of folate-dependent methionine cycle and is associated with oxidative stress. In a case control study, we evaluated eighty 3-5 years old Omani children (40 diagnosed with Autism Spectrum Disorder and 40 their age and gender matched controls) for their fasting serum homocysteine levels as a biomarker of Autism Spectrum Disorder (ASD). Serum folate and vitamin B(12) status were also evaluated. The serum homocysteine was measured using an enzyme immunoassay (EIA) technique whereas folate and vitamin B(12) were measured using an automated random access immune-assay system. The results indicated that mean serum Hcy levels were significantly (P < 0.05) higher in autistic children (20.1 ± 3.3 µmol/L) as compared to controls (9.64 ± 2.1 µmol/L). Significantly (P < 0.05) lower serum folate (1.8 ± 0.4 µg/L) and vitamin B(12) (191.1 ± 0.9 pg/mL) levels were observed in autistic children as compared to controls (6.1 ± 0.6 µg/L and 288.9 ± 1.3 pg/mL, respectively). The levels of homocysteine in autistic children were also much higher as compared to normal reference values (5-15 µmol/L). The results suggest that high fasting serum homocysteine and low folate and vitamin B(12) levels could be used as clinical biomarkers for an early diagnosis and management of ASD.


2017 ◽  
Vol 32 (7) ◽  
pp. 440-445
Author(s):  
L. Pulido Fontes ◽  
M. Pulido Fontes ◽  
P. Quesada Jiménez ◽  
J. Muruzabal Pérez ◽  
M. Mendioroz Iriarte

2017 ◽  
Vol 4 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Iram Qazi ◽  
◽  
Naina Kala Dogra ◽  
Devraj Dogra ◽  
◽  
...  

2021 ◽  
Author(s):  
Gunhild Falleth Sandvik ◽  
Svend Rand‐Hendriksen ◽  
Liv Drolsum ◽  
Olav Kristianslund

2002 ◽  
Vol 14 (10) ◽  
pp. 1113-1118 ◽  
Author(s):  
Gonzalo Castillo-Rojas ◽  
M. Arturo Ballesteros ◽  
Sergio Ponce de León ◽  
Rosario Morales-Espinosa ◽  
Alejandro Cravioto ◽  
...  

Author(s):  
Giri B. Laya ◽  
Amaranathan Anandhi ◽  
Balakrishnan Gurushankari ◽  
Jharna Mandal ◽  
Vikram Kate

2010 ◽  
Vol 104 (5) ◽  
pp. 757-764 ◽  
Author(s):  
Kentaro Murakami ◽  
Yoshihiro Miyake ◽  
Satoshi Sasaki ◽  
Keiko Tanaka ◽  
Wakaba Fukushima ◽  
...  

Increased homocysteine levels might accelerate dopaminergic cell death in Parkinson's disease (PD) through neurotoxic effects; thus, increasing intake of B vitamins involved in the regulation of homocysteine metabolism might decrease the risk of PD through decreasing plasma homocysteine. However, epidemiological evidence for the association of dietary B vitamins with PD is sparse, particularly in non-Western populations. We conducted a hospital-based case–control study in Japan to examine associations between dietary intake of folate, vitamin B6, vitamin B12 and riboflavin and the risk of PD. Patients with PD diagnosed using the UK PD Society Brain Bank criteria (n 249) and controls without neurodegenerative diseases (n 368) were recruited. Dietary intake during the preceding month was assessed at the time of study recruitment using a validated, self-administered, semi-quantitative, comprehensive diet history questionnaire. After adjustment for potential dietary and non-dietary confounding factors, intake of folate, vitamin B12 and riboflavin was not associated with the risk of PD (P for trend = 0·87, 0·70 and 0·11, respectively). However, low intake of vitamin B6 was associated with an increased risk of PD, independent of potential dietary and non-dietary confounders. Multivariate OR (95 % CI) for PD in the first, second, third and fourth quartiles of vitamin B6 were 1 (reference), 0·56 (0·33, 0·94), 0·69 (0·38, 1·25) and 0·48 (0·23, 0·99), respectively (P for trend = 0·10). In conclusion, in the present case–control study in Japan, low intake of vitamin B6, but not of folate, vitamin B12 or riboflavin, was independently associated with an increased risk of PD.


GERMS ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 182-187 ◽  
Author(s):  
Christina Tsigalou ◽  
Theocharis G Konstantinidis ◽  
Dimitrios Cassimos ◽  
Alexandros Karvelas ◽  
Anastasia Grapsa ◽  
...  

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