Renin–angiotensin system blockers are associated with reduced mortality and heart failure hospitalization in patients paced for complete atrioventricular block

Heart Rhythm ◽  
2012 ◽  
Vol 9 (4) ◽  
pp. 505-510 ◽  
Author(s):  
Douglas H.J. Elder ◽  
Chim C. Lang ◽  
Sushma Rekhraj ◽  
Benjamin Szwejkowski ◽  
Jacob George ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrioventricular Block ◽  
Renin Angiotensin System ◽  
Complete Atrioventricular Block ◽  
Heart Failure Hospitalization ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Complete Atrioventricular ◽  
Renin Angiotensin System Blockers

scholarly journals Non-employment and low educational level as risk factors for inequitable treatment and mortality in heart failure: a population-based cohort study of register data

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Anna Ohlsson ◽  
Nils Eckerdal ◽  
Bertil Lindahl ◽  
Marianne Hanning ◽  
Ragnar Westerling
Keyword(s):  
Heart Failure ◽  
Risk Factor ◽  
Cohort Study ◽  
Educational Level ◽  
Employment Status ◽  
Renin Angiotensin System ◽  
Access To Treatment ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Renin Angiotensin System Blockers

Abstract Background The risk of heart failure is disproportionately high among the socioeconomically disadvantaged. Furthermore, socioeconomically deprived patients are at risk of inequitable access to heart failure treatment and poor outcomes. Non-employment as a risk factor in this respect has not previously been studied at the level of the individual. The aim of this register-based cohort study was to analyse equity in access to renin-angiotensin system blockers and mortality, by employment status and educational level. Methods The study population consisted of Swedish patients aged 20–64 years hospitalised for heart failure in July 2006–December 2010, without a heart failure hospitalisation within one year or more before index hospitalisation and without renin-angiotensin system blocker dispensation in the 6 months preceding index hospitalisation. Non-access to renin-angiotensin system blockers, measured as drug dispensations, was investigated by employment status and educational level through logistic regression. Cox regression models were used to obtain hazard ratios for all-cause death by educational level and employment status. Interaction analysis was used to test whether associations between access to treatment and mortality differed by employment status. Results Among the 3874 patients, 1239 (32%) were women. The median age was 57 years. Fifty-three percent were employed. The non-employed patients had more comorbidity and lower access (68%) to renin-angiotensin system blockers compared with the employed (82%). The adjusted odds ratio for non-access to renin-angiotensin system blockers among the non-employed was 1.76. Non-employment was associated with an adjusted hazard ratio of 1.76 for death. Low educational level was associated with a higher death risk. Mortality was highest among the non-employed without access to renin-angiotensin system blockers and the association between access to renin-angiotensin system blockers and survival was slightly weaker in this group. Conclusions Non-employment and low educational level were associated with elevated mortality in heart failure. Non-employment was a risk factor for lower access to evidence-based treatment, and among the non-employed access to treatment was associated with a slightly smaller risk reduction than among the employed. The results underscore that clinicians need to be aware of the importance of socioeconomic factors in heart failure care.

Relation Between Renin-Angiotensin System Blockers and Survival Following Isolated Aortic Valve Replacement for Aortic Stenosis

2018 ◽  
Vol 121 (4) ◽  
pp. 455-460 ◽  
Author(s):  
Julien Magne ◽  
Barthélémy Guinot ◽  
Alexandre Le Guyader ◽  
Emmanuelle Bégot ◽  
Jean-Philippe Marsaud ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Stenosis ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Renin Angiotensin System Blockers
Sign in / Sign up

Export Citation Format

Share Document