scholarly journals The natural history of non-resected ipmn of the pancreas: A single institution experience

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e748-e749
Author(s):  
M. Del Chiaro ◽  
R. Segersvard ◽  
L. Nilsson ◽  
J. Blomberg ◽  
E. Rangelova ◽  
...  
Keyword(s):  
Natural History ◽  
Single Institution ◽  
History Of

Merkel Cell Carcinoma: Prognosis and Treatment of Patients From a Single Institution

2005 ◽  
Vol 23 (10) ◽  
pp. 2300-2309 ◽  
Author(s):  
Peter J. Allen ◽  
Wilbur B. Bowne ◽  
David P. Jaques ◽  
Murray F. Brennan ◽  
Klaus Busam ◽  
...  
Keyword(s):  
Natural History ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Merkel Cell ◽  
Nodal Staging ◽  
Single Institution ◽  
Node Negative ◽  
Nodal Recurrence ◽  
History Of

PurposeMerkel cell carcinoma (MCC) is an uncommon cutaneous malignancy. Most reports consist of single-institution experiences of fewer than 30 patients. The natural history of MCC is poorly defined.Patients and MethodsA review was performed of Memorial Sloan-Kettering Cancer Center's MCC database, identifying 251 patients who had been treated between 1970 and 2002. Patient, tumor, and treatment-related factors were analyzed for their association with recurrence and survival.ResultsThe average follow-up for all patients was 40 months and 46 months for patients alive at last follow-up. The 5-year disease-specific survival rate was 64%. Disease stage was the only independent predictor of survival (stage I, 81%; stage II, 67%; stage III, 52%; stage IV, 11%; P = .001). Pathologic staging of the draining nodal basin was performed in 71 (40%) of 177 patients who presented with clinically negative nodes, and 16 of these patients (23%) were found to have node-positive disease. Pathologic nodal staging was associated with improved stage-specific survival probabilities (clinical node-negative, 75% v pathologic node-negative disease, 97%; P = .009) and decreased nodal recurrence (44% v 11%, P < .001). The median time to recurrence was 9 months, and 102 patients (43%) recurred. Local recurrence developed in 8% of patients after margin-negative excision.ConclusionThese data demonstrate that the natural history of MCC is variable and dependent on the stage of disease at presentation. Pathologic nodal staging identifies a group of patients with excellent long-term survival. After margin-negative excision and pathologic nodal staging, local and nodal recurrence rates are low.

The natural history of sacrococcygeal teratomas diagnosed through routine obstetric sonogram: A single institution experience

1998 ◽  
Vol 33 (6) ◽  
pp. 899-903 ◽  
Author(s):  
Ai-Xuan Holterman ◽  
Denis Filiatrault ◽  
Michel Lallier ◽  
Sami Youssef
Keyword(s):  
Natural History ◽  
Single Institution ◽  
History Of

scholarly journals Natural History Of Grade I-Ii Blunt Traumatic Aortic Injury: A 10-Year Single Institution Observational Analysis

2013 ◽  
Vol 57 (5) ◽  
pp. 30S-31S ◽  
Author(s):  
Michael J. Osgood ◽  
Stacey L. Doran ◽  
Eric Rellinger ◽  
Josh Heck ◽  
Clifford L. Garrard ◽  
...  
Keyword(s):  
Natural History ◽  
Aortic Injury ◽  
Single Institution ◽  
Observational Analysis ◽  
History Of ◽  
Blunt Traumatic Aortic Injury

scholarly journals Natural History of 321 Flatfoot Reconstruction Patients Over a 14 Year Period Performed at a Single Institution

2019 ◽  
Vol 4 (4) ◽  
pp. 2473011419S0018
Author(s):  
Madison Goss ◽  
Chris Stauch ◽  
Joseph Lewcun ◽  
Jesse King ◽  
Madelaine Fritsche ◽  
...  
Keyword(s):  
Relative Risk ◽  
Natural History ◽  
Treatment Failure ◽  
Female Gender ◽  
Wound Complications ◽  
Single Institution ◽  
Number Of Patients ◽  
Surgical Data ◽  
History Of ◽  
Risk Of Treatment

Category: Midfoot/Forefoot Introduction/Purpose: Outcomes following surgical reconstruction for acquired flatfoot deformity secondary to posterior tibial tendon dysfunction have been well described. However, the majority of studies have a limited number of patients or short to mid- term follow-up. The purpose of this study was to report the natural history, demographics, and mechanisms of treatment failure for patients undergoing flatfoot reconstruction at a single institution by a single surgeon. Methods: With IRB approval, 321 consecutive patients undergoing flatfoot reconstruction during a 14-year period were included in this study (February 2002 through October 2016). All procedures were performed by a single surgeon (PJJ) at our institution. Demographic data, surgical data, clinic notes, and radiographs were available for review. Exclusion criteria included patients without electronic records or incomplete data. Failure was defined as a need to return to the operating room for revision surgery. Statistical analysis was performed. Results: 321 consecutive patients underwent flatfoot reconstruction from 2002-2016. The majority of patients were female (83.2%) with left laterality (58.6%) & a body mass index classified as overweight (21.5%) or obese (56.4%). 13.7% of patients were diabetics, and 18.4% were current smokers. 54 patients (16.8%) experienced treatment failure. Painful calcaneal hardware requiring removal occurred in 11.8% of patients, conversion to triple arthrodesis occurred in 3.45%, and wound complications or infection requiring irrigation & debridement occurred in 1.87%. There were no mortalities reported within 90 days. There were 3 symptomatic deep vein thromboses, none requiring surgical intervention, & no pulmonary embolisms. A significant increase in relative risk of treatment failure was calculated for female gender, current cigarette use, & age under 60 (3.4 p=0.0005/1.9 p=0.0081/1.8 p=0.042). Conclusion: This study represents the largest series of patients undergoing flatfoot reconstruction by a single surgeon at a single institution. Although retrospective, the results provide valuable insight to the natural history of patients undergoing this procedure. The overall complication rate and treatment failure rates are low and similar to those previously reported in the literature. Patients with female gender or under 60 years of age should be notified of their increased relative risk of treatment failure & counseled accordingly. Smoking cessation is recommended to reduce the risk of treatment failure.

Risk factors, clinical outcomes, and natural history of uveal melanoma: a single-institution analysis

2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Glenda M. Delgado-Ramos ◽  
Fridtjof Thomas ◽  
Ari VanderWalde ◽  
Benjamin King ◽  
Matthew Wilson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Natural History ◽  
Clinical Outcomes ◽  
Uveal Melanoma ◽  
Single Institution ◽  
History Of

Risk factors, clinical outcomes, and natural history of uveal melanoma: A single institution analysis.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e21631-e21631
Author(s):  
Glenda Maria Delgado Ramos ◽  
Fridtjof Thomas ◽  
Ari M. Vanderwalde ◽  
Matthew W. Wilson ◽  
Arnel M. Pallera
Keyword(s):  
Risk Factors ◽  
Natural History ◽  
Clinical Outcomes ◽  
Uveal Melanoma ◽  
Single Institution ◽  
History Of

scholarly journals VESS13. Natural History of Renal Artery Aneurysms: An 18-Year Single-Institution Experience

2014 ◽  
Vol 59 (6) ◽  
pp. 9S
Author(s):  
Ziqing Wang ◽  
Peter Pak ◽  
Caron B. Rockman ◽  
Alec Megibow ◽  
Neal S. Cayne
Keyword(s):  
Natural History ◽  
Renal Artery ◽  
Single Institution ◽  
History Of

How is the moral stance related to the intentional stance and group thinking?

2020 ◽  
Vol 43 ◽  
Author(s):  
Hannes Rakoczy
Keyword(s):  
Natural History ◽  
Social Cognitive ◽  
Intentional Stance ◽  
Cognitive Capacities ◽  
Shared Intentionality ◽  
History Of ◽  
Group Thinking ◽  
Moral Stance

Abstract The natural history of our moral stance told here in this commentary reveals the close nexus of morality and basic social-cognitive capacities. Big mysteries about morality thus transform into smaller and more manageable ones. Here, I raise questions regarding the conceptual, ontogenetic, and evolutionary relations of the moral stance to the intentional and group stances and to shared intentionality.

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