EUS to predict cure of gastric mucosa–associated lymphoma after Helicobacter pylori eradication

2007 ◽  
Vol 65 (1) ◽  
pp. 97-98 ◽  
Author(s):  
Hiroto Kita
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Mucosa ◽  
Helicobacter Pylori Eradication

Su1179 Magnifying NBI Patterns of Gastric Mucosa After Helicobacter Pylori Eradication and its Potential Link to the Gastric Cancer Risk

2017 ◽  
Vol 85 (5) ◽  
pp. AB303
Author(s):  
Tomomitsu Tahara ◽  
Sayumi Tahara ◽  
Tetsuya Tsukamoto ◽  
Noriyuki Horiguchi ◽  
Tomohiko Kawamura ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Gastric Mucosa ◽  
Cancer Risk ◽  
Gastric Cancer Risk ◽  
Helicobacter Pylori Eradication ◽  
Potential Link

Helicobacter pylori eradication attenuates oxidative stress in human gastric mucosa

2001 ◽  
Vol 96 (6) ◽  
pp. 1758-1766 ◽  
Author(s):  
Brigitte Pignatelli ◽  
Brigitte Bancel ◽  
Martin Plummer ◽  
Shinya Toyokuni ◽  
Louis-Marc Patricot ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Helicobacter Pylori ◽  
Gastric Mucosa ◽  
Human Gastric Mucosa ◽  
Helicobacter Pylori Eradication

P53-positive cells in the gastric mucosa before and after Helicobacter pylori eradication

2000 ◽  
Vol 118 (4) ◽  
pp. A751
Author(s):  
Kiichi Satoh ◽  
Ken Kihira ◽  
Hiroshi Kawata ◽  
Keiko Fukazawa ◽  
Satoshi Kawakami ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Mucosa ◽  
Helicobacter Pylori Eradication ◽  
Before And After

Magnifying Narrow-Band Imaging (NBI) Features of Gastric Mucosa Associated with Irreversibleness with Helicobacter Pylori Eradication and Downregulation of MIR-124A

2017 ◽  
Vol 152 (5) ◽  
pp. S839
Author(s):  
Tomomitsu Tahara ◽  
Sayumi Tahara ◽  
Tetsuya Tsukamoto ◽  
Noriyuki Horiguchi ◽  
Tomohiko Kawamura ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastric Mucosa ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Helicobacter Pylori Eradication

Morphologic Characterization of Residual DNA Methylation in the Gastric Mucosa after Helicobacter Pylori Eradication

2017 ◽  
Vol 152 (5) ◽  
pp. S835
Author(s):  
Sayumi Tahara ◽  
Tomomitsu Tahara ◽  
Tetsuya Tsukamoto ◽  
Noriyuki Horiguchi ◽  
Tomohiko Kawamura ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Helicobacter Pylori ◽  
Gastric Mucosa ◽  
Helicobacter Pylori Eradication

scholarly journals Effect of Helicobacter pylori Eradication on Epigenetic Changes in Gastric Cancer-related Genes

2021 ◽  
Vol 21 (4) ◽  
pp. 256-266
Author(s):  
Ji Min Choi ◽  
Sang Gyun Kim
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Gastric Mucosa ◽  
Gastric Carcinogenesis ◽  
Point Of View ◽  
Epigenetic Changes ◽  
Epigenetic Alterations ◽  
Helicobacter Pylori Eradication ◽  
Gastric Cancer Prevention ◽  
H Pylori

It is known that gastric carcinogenesis results from the progressive changes from chronic gastritis to gastric atrophy, intestinal metaplasia, dysplasia, and invasive carcinoma. Several genetic and epigenetic alterations are involved in this process, and Helicobacter pylori (H. pylori) infection is believed to induce the initiation and progression of these steps. From an epigenetic point of view, H. pylori induces hypermethylation of genes involved in the development of gastric cancer and regulates the expression of various microRNAs (miRNAs). These H. pylori-related epigenetic changes are accumulated not only at the site of neoplasm but also in the adjacent non-cancerous gastric mucosa. Thereby, a state vulnerable to gastric cancer known as an epigenetic field defect is formed. H. pylori eradication can have an effective chemopreventive effect in gastric carcinogenesis. However, the molecular biological changes that occur in the stomach environment during H. pylori eradication have not yet been established. Several studies have reported that H. pylori eradication can restore infection-related changes, especially epigenetic alterations in gastric cancer-related genes, but some studies have shown otherwise. Simply put, it appears that the recovery of methylated gastric cancer-related genes and miRNAs during H. pylori eradication may vary among genes and may also differ depending on the histological subtype of the gastric mucosa. In this review, we will discuss the potential mechanism of gastric cancer prevention by H. pylori eradication, mainly from an epigenetic perspective.

Sign in / Sign up

Export Citation Format

Share Document