Synonymous codon usage pattern in glycoprotein gene of rabies virus

Gene ◽  
2016 ◽  
Vol 584 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Sudhir Morla ◽  
Aditi Makhija ◽  
Sachin Kumar
Keyword(s):  
Codon Usage ◽  
Rabies Virus ◽  
Synonymous Codon ◽  
Synonymous Codon Usage ◽  
Codon Usage Pattern ◽  
Usage Pattern ◽  
Glycoprotein Gene

Synonymous codon usage pattern analysis of Hepatitis D virus

2013 ◽  
Vol 173 (2) ◽  
pp. 350-353 ◽  
Author(s):  
Arghya Kamal Bishal ◽  
Rashmi Mukherjee ◽  
Chandan Chakraborty
Keyword(s):  
Codon Usage ◽  
Pattern Analysis ◽  
Synonymous Codon ◽  
Synonymous Codon Usage ◽  
Codon Usage Pattern ◽  
Usage Pattern ◽  
Hepatitis D ◽  
Hepatitis D Virus

Characterization of Codon Usage Bias in the UL55 Gene of Duck Enteritis Virus

2011 ◽  
Vol 204-210 ◽  
pp. 649-662 ◽  
Author(s):  
Ying Wu ◽  
An Chun Cheng ◽  
Ming Shu Wang ◽  
De Kang Zhu ◽  
Xiao Yue Chen
Keyword(s):  
Codon Usage ◽  
Codon Usage Bias ◽  
Synonymous Codon ◽  
Synonymous Codon Usage ◽  
Duck Enteritis Virus ◽  
Codon Usage Pattern ◽  
Usage Pattern ◽  
E Coli ◽  
Usage Patterns ◽  
Enteritis Virus

The analysis of codon usage may improve our understanding of the evolution and pathogenesis of DEV（Duck enteritis virus） and allow reengineering of target gene to improve their expression for gene therapy.In this study,we calculated the codon usage bias in DEV UL55 gene and performed a comparative analysis of synonymous codon usage patterns in other 26 related viruses by EMBOSS CUSP program and Codon W on line.Moreover,statistical methods were used to investigate the correlations of these related parameters. By comparing synonymous codon usage patterns in different viruses,we observed that synonymous codon usage pattern in these virus is virus specific and phylogenetically conserved, with a strong bias towards the codons with A and T at the third codon position. Phylogenetic analysis based on codon usage pattern suggested that DEV UL55 gene was clustered with the avian Alphaherpesvirus but diverged to form a single branch. The Neutrality-plot suggested GC12 and GC3s adopt the same mutation pattern,meanwhile,the ENC-plot revealed that the genetic heterogeneity in UL55 genes is constrained by the G+C content, while translational selection and gene length have no or micro effect on the variations of synonymous codon usage in these virus genes.Furthermore, we compared the codon preferences of DEV with those of E. coli, yeast and Homo sapiens.Data suggested the eukaryotes system such as human system may be more suitable for the expression of DEV UL55 gene in vitro. If the yeast and E. coli expression system are wanted for the expression of DEV UL55 gene ,codon optimization of the DEV UL55 gene may be required.

scholarly journals Phylogenetic and Codon Usage Analysis for Capsid and Replicase Genes of Porcine Circovirus 3

2021 ◽  
Author(s):  
Xianglong Yu ◽  
Kuipeng Gao ◽  
Molin Pi ◽  
Huizi Li ◽  
Wenxia Zhong ◽  
...  
Keyword(s):  
Codon Usage ◽  
Synonymous Codon ◽  
Economic Loss ◽  
Porcine Circovirus Type ◽  
Synonymous Codon Usage ◽  
Porcine Circovirus ◽  
Codon Usage Pattern ◽  
Usage Pattern ◽  
Swine Industry ◽  
Usage Analysis

Abstract Porcine circovirus type 3 (PCV3) is a highly contagious virus belonging to the family Circoviridae that causes the severe dermatitis and nephropathy syndrome. To date, PCV3 has a worldwide distribution and bring huge economic loss in swine industry. Replicase protein (Rep) and capsid protein (Cap) are two major proteins of PCV3. Considering that the large number of new PCV3 isolates were reported in the past few years and the research for the codon usage pattern of Rep and Cap genes was still a gap, phylogenetic and codon usage analysis of these two genes was performed. Phylogenetic analysis with all strains showed no clear clusters were displayed, but almost all strains of one genotype were separated into same clade. Relative synonymous codon usage (RSCU) analysis revealed that the codon usage bias existed and effective number of codon (ENC) analysis showed that the bias was slight low. ENC-GC3s plot indicated that mutational pressure and other factors both play a role in PCV3 codon usage and neutrality plot analysis showed that natural selection was the main force influencing the codon usage pattern. In summary, the results provided the important basic data on codon usage pattern of Rep and Cap genes, and a better understanding of the evolution and potential origin of PCV3.

In silico Analysis of Synonymous Codon Usage Pattern of Rhizobium etli CFN 42

2014 ◽  
Vol 86 (2) ◽  
pp. 385-393
Author(s):  
Mohammad Samir Farooqi ◽  
R. K. Sanjukta ◽  
Dwijesh Chandra Mishra ◽  
Dhananjaya Pratap Singh ◽  
Anil Rai ◽  
...  
Keyword(s):  
Codon Usage ◽  
In Silico ◽  
Synonymous Codon ◽  
In Silico Analysis ◽  
Synonymous Codon Usage ◽  
Codon Usage Pattern ◽  
Usage Pattern ◽  
Rhizobium Etli ◽  
Silico Analysis

Analysis of synonymous codon usage pattern of genes in unique non–blood‐sucking leech Whitmania pigra

2019 ◽  
Vol 120 (6) ◽  
pp. 9850-9858
Author(s):  
Muhammad Salabat Khan ◽  
De‐Long Guan ◽  
Li‐Bin Ma ◽  
Juan‐Ying Xie ◽  
Sheng‐Quan Xu
Keyword(s):  
Codon Usage ◽  
Synonymous Codon ◽  
Synonymous Codon Usage ◽  
Codon Usage Pattern ◽  
Usage Pattern ◽  
Blood Sucking ◽  
Whitmania Pigra

Analysis of synonymous codon usage pattern in duck circovirus

Gene ◽  
2015 ◽  
Vol 557 (2) ◽  
pp. 138-145 ◽  
Author(s):  
Yu Xu ◽  
Renyong Jia ◽  
Zhilong Zhang ◽  
Yanyan Lu ◽  
Mingshu Wang ◽  
...  
Keyword(s):  
Codon Usage ◽  
Synonymous Codon ◽  
Synonymous Codon Usage ◽  
Codon Usage Pattern ◽  
Usage Pattern ◽  
Duck Circovirus

scholarly journals The characteristics of the synonymous codon usage in enterovirus 71 virus and the effects of host on the virus in codon usage pattern

2011 ◽  
Vol 11 (5) ◽  
pp. 1168-1173 ◽  
Author(s):  
Yong-sheng Liu ◽  
Jian-hua Zhou ◽  
Hao-tai Chen ◽  
Li-na Ma ◽  
Zygmunt Pejsak ◽  
...  
Keyword(s):  
Codon Usage ◽  
Synonymous Codon ◽  
Enterovirus 71 ◽  
Synonymous Codon Usage ◽  
Codon Usage Pattern ◽  
Usage Pattern
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