Thrombophilic genetic factors PAI-1 4G-4G and MTHFR 677TT as risk factors of alcohol, cryptogenic liver cirrhosis and portal vein thrombosis, in a Caucasian population

Gene ◽  
2015 ◽  
Vol 568 (1) ◽  
pp. 85-88 ◽  
Author(s):  
Mario D'Amico ◽  
Francesca Pasta ◽  
Linda Pasta
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Genetic Factors ◽  
Caucasian Population ◽  
Vein Thrombosis ◽  
Pai 1

scholarly journals Sport-Related Portal Vein Thrombosis: An Unusual Complication

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Igor Dumic ◽  
Nikola Tankosic ◽  
Milica Stojkovic Lalosevic ◽  
Tamara Alempijevic
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Unusual Complication ◽  
Minimal Risk ◽  
Vein Thrombosis ◽  
First Case ◽  
Uncommon Condition ◽  
Traditional Risk Factors

Portal vein thrombosis (PVT) is an uncommon condition usually associated with hypercoagulable states or liver cirrhosis. PVT due to sports-related injuries is rarely reported and, to the best of our knowledge, only two cases have been reported thus far. Brazilian jiu-jitsu (BJJ) is a form of martial arts and is considered very safe with minimal risk for injury. It has growing popularity worldwide. Here, we report the first case of PVT secondary to abdominal trauma related to the practice of (BJJ) in an otherwise healthy 32-year-old man with no other traditional risk factors for PVT.

scholarly journals Risk factors of portal vein thrombosis after splenectomy in patients with liver cirrhosis

2020 ◽  
Vol 2020 ◽  
Author(s):  
Ze-long Yang ◽  
Ting Guo ◽  
Dong-Lie Zhu ◽  
Shi Zheng ◽  
Dan-Dan Han ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Vein Thrombosis

Thrombotic risk factors in patients with liver cirrhosis: Correlation with MELD scoring system and portal vein thrombosis development

2009 ◽  
Vol 51 (4) ◽  
pp. 682-689 ◽  
Author(s):  
Maria Assunta Zocco ◽  
Enrico Di Stasio ◽  
Raimondo De Cristofaro ◽  
Marialuisa Novi ◽  
Maria Elena Ainora ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Scoring System ◽  
Thrombotic Risk ◽  
Vein Thrombosis

scholarly journals Portal vein thrombosis in patients with liver cirrhosis: Risk factors and clinical presentation

2021 ◽  
Author(s):  
Sondes Bizid ◽  
Houssaina Jlassi ◽  
Maroua Ben Abbes ◽  
Ghanem Mohamed ◽  
Hela Ghedira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Liver Disease ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Anticoagulation Therapy ◽  
Factor V Leiden ◽  
Factor V Leiden Mutation ◽  
Vein Thrombosis ◽  
Increased Risk

Abstract Background:Portal vein thrombosis (PVT) is a common complication of liver cirrhosis. PVT impact on disease progression is not clarified as yet. Anticoagulation therapy is considered effective in this setting, but is associated with potentially bleeding episodes. Aim : to assess the risk factors and clinical impact of non-neoplastic PVT complicating cirrhosis, as well as the treatment profile and its efficacy in clinical practice.Methods:A retrospective monocentric study over a period of 19 years including all patients diagnosed with cirrhosis and non-neoplastic PVT was conducted.Results:A total of 49 patients were enrolled in the present study.The mean age was 60.86±11.61 years old. Chronic viral hepatitis was the most frequent cause of cirrhosis (63.2%). Most of our cases had advanced liver disease (89.9% Child class B/C) with a mean MELD score of 19.27. The risk factors for thrombophilia, inherited or acquired, were: a deficiency in coagulation inhibitors, either isolated or combined (protein S, protein C and antithrombin III) in 19 patients, a heterozygous Factor V Leiden mutation in 2 patients, a heterozygous MTHFR mutation in one patient, an antiphospholipid antibodies syndrome in 2 patients, an essential thrombocythemia in one patient. Anticoagulant therapy was indicated in half of the cases. Multivariate analyses demonstrated that thrombus extension was the only independent predictive factor of portal vein recanalization (p=0.009). During follow-up, progression was observed in 8% of treated patients with anticoagulants versus 12.5% of untreated patients (p=0.12). Our study has shown that anticoagulant treatment is not associated with elevated risk of bleeding or developing other complications. The mean survival was higher in patients treated successfully (38.31 months Vs 23.41 months, p=0.204). Conclusions:Our outcomes confirm that anticoagulation therapy in cirrhotic patients with non-neoplastic PVT is not associated with increased risk of liver disease decompensation, including bleeding.

PORTAL VEIN THROMBOSIS IN PATIENTS WITH LIVER CIRRHOSIS ;RISK FACTORS,CLINICAL PRESENTATION AND OUTCOME

2013 ◽  
Vol 19 (5) ◽  
pp. 1-12
Author(s):  
Afifi Afifi ◽  
Osama Basha ◽  
Ahmed Gomaa ◽  
Abdelaziz samack ◽  
Raghda Elsherbini
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Clinical Presentation ◽  
Vein Thrombosis

scholarly journals The risk factors of portal vein thrombosis in patients with liver cirrhosis

2019 ◽  
Author(s):  
Yasir Cagin ◽  
Yilmaz Bilgic ◽  
İlhami Berber ◽  
Oguzhan Yildirim ◽  
Mehmet Erdogan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Vein Thrombosis
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