Testis-specific expression and genomic multiplicity of the rat Rtdpoz genes that encode bipartite TRAF- and POZ/BTB-domain proteins

Gene ◽  
2007 ◽  
Vol 387 (1-2) ◽  
pp. 141-149 ◽  
Author(s):  
Kong-Bung Choo ◽  
Min-Chuan Hsu ◽  
Kowit-Yu Chong ◽  
Chiu-Jung Huang
Keyword(s):  
Specific Expression ◽  
Btb Domain ◽  
Testis Specific Expression

scholarly journals Testis-specific expression of a novel mouse defensin-like gene, Tdl

2002 ◽  
Vol 116 (1-2) ◽  
pp. 217-221 ◽  
Author(s):  
Miwako Yamamoto ◽  
Yasuhisa Matsui
Keyword(s):  
Specific Expression ◽  
Testis Specific Expression

The testis-specific expression pattern of the growth hormone/placental lactogen (GH/PL) gene cluster changes with malignancy

1999 ◽  
Vol 30 (10) ◽  
pp. 1201-1206 ◽  
Author(s):  
Peter Berger ◽  
Gerold Untergasser ◽  
Martin Hermann ◽  
Anton Hittmair ◽  
Stephan Madersbacher ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Gene Cluster ◽  
Expression Pattern ◽  
Placental Lactogen ◽  
Specific Expression ◽  
Specific Expression Pattern ◽  
Testis Specific Expression

scholarly journals Sexually Antagonistic Mitonuclear Coevolution in Duplicate Oxidative Phosphorylation Genes

2019 ◽  
Vol 59 (4) ◽  
pp. 864-874 ◽  
Author(s):  
Justin C Havird ◽  
Hunter J McConie
Keyword(s):  
Oxidative Phosphorylation ◽  
Structural Data ◽  
Mitochondrial Genomes ◽  
Duplicate Genes ◽  
Gene Products ◽  
Mitochondrial Mutations ◽  
Specific Expression ◽  
Chimeric Enzymes ◽  
Rates Of Evolution ◽  
Testis Specific Expression

Abstract Mitochondrial function is critical in eukaryotes. To maintain an adequate supply of energy, precise interactions must be maintained between nuclear- and mitochondrial-encoded gene products. Such interactions are paramount in chimeric enzymes such as the oxidative phosphorylation (OXPHOS) complexes. Mutualistic coevolution between the two genomes has therefore been suggested to be a critical, ubiquitous feature of eukaryotes that acts to maintain cellular function. However, mitochondrial genomes can also act selfishly and increase their own transmission at the expense of organismal function. For example, male-harming mutations are predisposed to accumulate in mitochondrial genomes due to their maternal inheritance (“mother’s curse”). Here, we investigate sexually antagonistic mitonuclear coevolution in nuclear-encoded OXPHOS paralogs from mammals and Drosophila. These duplicate genes are highly divergent but must interact with the same set of mitochondrial-encoded genes. Many such paralogs show testis-specific expression, prompting previous hypotheses suggesting they may have evolved under selection to counteract male-harming mitochondrial mutations. We found increased rates of evolution in OXPHOS paralogs with testis-specific expression in mammals and Drosophila, supporting this hypothesis. However, further analyses suggested such patterns may be due to relaxed, not positive selection, especially in Drosophila. Structural data also suggest that mitonuclear interactions do not play a major role in the evolution of many OXPHOS paralogs in a consistent way. In conclusion, no single OXPHOS paralog met all our criteria for being under selection to counteract male-harming mitochondrial mutations. We discuss alternative explanations for the drastic patterns of evolution in these genes, including mutualistic mitonuclear coevolution, adaptive subfunctionalization after gene duplication, and relaxed selection on OXPHOS in male tissues.

scholarly journals Identification and Expression Profiling of the BTB Domain-Containing Protein Gene Family in the Silkworm,Bombyx mori

2014 ◽  
Vol 2014 ◽  
pp. 1-14 ◽  
Author(s):  
Daojun Cheng ◽  
Wenliang Qian ◽  
Meng Meng ◽  
Yonghu Wang ◽  
Jian Peng ◽  
...  
Keyword(s):  
Protein Gene ◽  
Domain Architecture ◽  
Gene Families ◽  
Monarch Butterfly ◽  
Duplication Event ◽  
Orthologous Relationship ◽  
Specific Expression ◽  
Protein Protein Interaction ◽  
Btb Domain ◽  
Silkworm Bombyx Mori

The BTB domain is a conserved protein-protein interaction motif. In this study, we identified 56 BTB domain-containing protein genes in the silkworm, in addition to 46 in the honey bee, 55 in the red flour beetle, and 53 in the monarch butterfly. Silkworm BTB protein genes were classified into nine subfamilies according to their domain architecture, and most of them could be mapped on the different chromosomes. Phylogenetic analysis suggests that silkworm BTB protein genes may have undergone a duplication event in three subfamilies: BTB-BACK-Kelch, BTB-BACK-PHR, and BTB-FLYWCH. Comparative analysis demonstrated that the orthologs of each of 13 BTB protein genes present a rigorous orthologous relationship in the silkworm and other surveyed insects, indicating conserved functions of these genes during insect evolution. Furthermore, several silkworm BTB protein genes exhibited sex-specific expression in larval tissues or at different stages during metamorphosis. These findings not only contribute to a better understanding of the evolution of insect BTB protein gene families but also provide a basis for further investigation of the functions of BTB protein genes in the silkworm.

scholarly journals A Large Expansion of the HSFY Gene Family in Cattle Shows Dispersion across Yq and Testis-Specific Expression

PLoS ONE ◽  
2011 ◽  
Vol 6 (3) ◽  
pp. e17790 ◽  
Author(s):  
Christine K. Hamilton ◽  
Tamas Revay ◽  
Robin Domander ◽  
Laura A. Favetta ◽  
W. Allan King
Keyword(s):  
Gene Family ◽  
Specific Expression ◽  
Large Expansion ◽  
Testis Specific Expression

scholarly journals The highly conserved NANOS2 protein: testis-specific expression and significance for the human male reproduction

2009 ◽  
Vol 15 (3) ◽  
pp. 165-171 ◽  
Author(s):  
K.M. Kusz ◽  
L. Tomczyk ◽  
M. Sajek ◽  
A. Spik ◽  
A. Latos-Bielenska ◽  
...  
Keyword(s):  
Male Reproduction ◽  
Specific Expression ◽  
Human Male ◽  
Testis Specific Expression

Promoter contribution to the testis-specific expression of Stellate gene family in Drosophila melanogaster

Gene ◽  
2012 ◽  
Vol 499 (1) ◽  
pp. 143-153 ◽  
Author(s):  
Oxana M. Olenkina ◽  
Ksenia S. Egorova ◽  
Mikhail V. Kibanov ◽  
Yuri V. Gervaziev ◽  
Vladimir A. Gvozdev ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Gene Family ◽  
Specific Expression ◽  
Testis Specific Expression
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