Disturbed Hsp70 and Hsp27 expression and thiol redox status in porcine kidney PK15 cells provoked by individual and combined ochratoxin A and citrinin treatments

2014 ◽  
Vol 71 ◽  
pp. 97-105 ◽  
Author(s):  
Maja Šegvić Klarić ◽  
Nevena Medić ◽  
Andrea Hulina ◽  
Tihana Žanić Grubišić ◽  
Lada Rumora
Keyword(s):  
Ochratoxin A ◽  
Redox Status ◽  
Porcine Kidney ◽  
Hsp27 Expression ◽  
Thiol Redox

scholarly journals Protocol for determining protein cysteine thiol redox status using western blot analysis

2021 ◽  
Vol 2 (2) ◽  
pp. 100566
Author(s):  
Bikram Datt Pant ◽  
Sunhee Oh ◽  
Kirankumar S. Mysore
Keyword(s):  
Western Blot ◽  
Blot Analysis ◽  
Western Blot Analysis ◽  
Redox Status ◽  
Thiol Redox

Thiol redox status critically influences mitochondrial response to thyroid hormone-induced hepatic oxidative injury: A temporal analysis

2010 ◽  
Vol 28 (2) ◽  
pp. 126-134 ◽  
Author(s):  
Sutapa Chattopadhyay ◽  
Dipak K. Sahoo ◽  
Anita Roy ◽  
Luna Samanta ◽  
Gagan B.N. Chainy
Keyword(s):  
Thyroid Hormone ◽  
Oxidative Injury ◽  
Temporal Analysis ◽  
Redox Status ◽  
Thiol Redox

Regulation of cellular thiol redox status by nitric oxide

1997 ◽  
Vol 27 (3) ◽  
pp. 157-177 ◽  
Author(s):  
Christine M. Padgett ◽  
A. Richard Whorton
Keyword(s):  
Nitric Oxide ◽  
Redox Status ◽  
Thiol Redox ◽  
Cellular Thiol

scholarly journals The Effectiveness of Glutathione Redox Status as a Possible Tumor Marker in Colorectal Cancer

2021 ◽  
Vol 22 (12) ◽  
pp. 6183
Author(s):  
Delia Acevedo-León ◽  
Lidia Monzó-Beltrán ◽  
Segundo Ángel Gómez-Abril ◽  
Nuria Estañ-Capell ◽  
Natalia Camarasa-Lillo ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Redox State ◽  
Reduced Glutathione ◽  
Redox Status ◽  
Oxidation Products ◽  
Interventional Study ◽  
Thiol Redox State ◽  
Thiol Redox ◽  
Glutathione Redox

The role of oxidative stress (OS) in cancer is a matter of great interest due to the implication of reactive oxygen species (ROS) and their oxidation products in the initiation of tumorigenesis, its progression, and metastatic dissemination. Great efforts have been made to identify the mechanisms of ROS-induced carcinogenesis; however, the validation of OS byproducts as potential tumor markers (TMs) remains to be established. This interventional study included a total of 80 colorectal cancer (CRC) patients and 60 controls. By measuring reduced glutathione (GSH), its oxidized form (GSSG), and the glutathione redox state in terms of the GSSG/GSH ratio in the serum of CRC patients, we identified significant changes as compared to healthy subjects. These findings are compatible with the effectiveness of glutathione as a TM. The thiol redox state showed a significant increase towards oxidation in the CRC group and correlated significantly with both the tumor state and the clinical evolution. The sensitivity and specificity of serum glutathione levels are far above those of the classical TMs CEA and CA19.9. We conclude that the GSSG/GSH ratio is a simple assay which could be validated as a novel clinical TM for the diagnosis and monitoring of CRC.

scholarly journals A novel and rapid apoptosis assay based on thiol redox status

2012 ◽  
Vol 81A (5) ◽  
pp. 430-436 ◽  
Author(s):  
Mette E. Skindersoe ◽  
Mikkel Rohde ◽  
Soeren Kjaerulff
Keyword(s):  
Redox Status ◽  
Apoptosis Assay ◽  
Thiol Redox
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