High-fructose corn syrup causes vascular dysfunction associated with metabolic disturbance in rats: Protective effect of resveratrol

2012 ◽  
Vol 50 (6) ◽  
pp. 2135-2141 ◽  
Author(s):  
Fatma Akar ◽  
Orhan Uludağ ◽  
Ali Aydın ◽  
Yasin Atacan Aytekin ◽  
Sehri Elbeg ◽  
...  
Keyword(s):  
Protective Effect ◽  
Vascular Dysfunction ◽  
Metabolic Disturbance ◽  
High Fructose Corn Syrup ◽  
Corn Syrup ◽  
High Fructose

scholarly journals Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats

2016 ◽  
Vol 2016 ◽  
pp. 1-8
Author(s):  
Aburrahman Gun ◽  
Mehmet Kaya Ozer ◽  
Sedat Bilgic ◽  
Nevin Kocaman ◽  
Gonca Ozan
Keyword(s):  
Metabolic Syndrome ◽  
Caffeic Acid ◽  
Vascular Function ◽  
Vascular Dysfunction ◽  
Caffeic Acid Phenethyl Ester ◽  
High Fructose Corn Syrup ◽  
Corn Syrup ◽  
Beneficial Effects ◽  
Fructose Intake ◽  
High Fructose

Fructose corn syrup is cheap sweetener and prolongs the shelf life of products, but fructose intake causes hyperinsulinemia, hypertriglyceridemia, and hypertension. All of them are referred to as metabolic syndrome and they are risk factors for cardiovascular diseases. Hence, the harmful effects of increased fructose intake on health and their prevention should take greater consideration. Caffeic Acid Phenethyl Ester (CAPE) has beneficial effects on metabolic syndrome and vascular function which is important in the prevention of cardiovascular disease. However, there are no known studies about the effect of CAPE on fructose-induced vascular dysfunction. In this study, we examined the effect of CAPE on vascular dysfunction due to high fructose corn syrup (HFCS). HFCS (6 weeks, 30% fed with drinking water) caused vascular dysfunction, but treatment with CAPE (50 micromol/kg i.p. for the last two weeks) effectively restored this problem. Additionally, hypertension in HFCS-fed rats was also decreased in CAPE supplemented rats. CAPE supplements lowered HFCS consumption-induced raise in blood glucose, homocysteine, and cholesterol levels. The aorta tissue endothelial nitric oxide synthase (eNOS) production was decreased in rats given HFCS and in contrast CAPE supplementation efficiently increased its production. The presented results showed that HFCS-induced cardiovascular abnormalities could be prevented by CAPE treatment.

Fructose and high fructose corn syrup: are they a two-edged sword?

2021 ◽  
pp. 1-23
Author(s):  
Nasim Khorshidian ◽  
Mahdi Shadnoush ◽  
Maryam Zabihzadeh Khajavi ◽  
Sara Sohrabvandi ◽  
Mojtaba Yousefi ◽  
...  
Keyword(s):  
High Fructose Corn Syrup ◽  
Corn Syrup ◽  
High Fructose

scholarly journals High-fructose corn syrup, energy intake, and appetite regulation

2008 ◽  
Vol 88 (6) ◽  
pp. 1738S-1744S ◽  
Author(s):  
Kathleen J Melanson ◽  
Theodore J Angelopoulos ◽  
Von Nguyen ◽  
Linda Zukley ◽  
Joshua Lowndes ◽  
...  
Keyword(s):  
Energy Intake ◽  
High Fructose Corn Syrup ◽  
Appetite Regulation ◽  
Corn Syrup ◽  
High Fructose
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