Fisetin, a novel flavonol attenuates benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice

2011 ◽  
Vol 49 (5) ◽  
pp. 1141-1147 ◽  
Author(s):  
Nagaiya Ravichandran ◽  
Gopalakrishnan Suresh ◽  
Balasubramanian Ramesh ◽  
Ganesan Vijaiyan Siva
2018 ◽  
Vol 34 (4) ◽  
pp. 355-363 ◽  
Author(s):  
Ravi Sakthivel ◽  
Dicson Sheeja Malar ◽  
Govindaraju Archunan ◽  
Kasi Pandima Devi

2011 ◽  
Vol 363 (1-2) ◽  
pp. 335-345 ◽  
Author(s):  
Selvamani Asokkumar ◽  
Chandrashekar Naveenkumar ◽  
Subramanian Raghunandhakumar ◽  
Sattu Kamaraj ◽  
Pandi Anandakumar ◽  
...  

2014 ◽  
Vol 10 (4) ◽  
pp. 1033 ◽  
Author(s):  
Dhanapal Sakthisekaran ◽  
Peramaiyan Rajendran ◽  
Thamaraiselvan Rengarajan ◽  
Ikuo Nishigaki ◽  
Ganapathy Ekambaram

2007 ◽  
Vol 3 (3) ◽  
pp. 143-150 ◽  
Author(s):  
Venkatraman Magesh ◽  
Ramachandran Venugopal ◽  
Konga Durga Bhavani ◽  
Dhanapal Sakthiseka

2013 ◽  
Vol 28 (3) ◽  
pp. 310-322 ◽  
Author(s):  
Chandrashekar Naveenkumar ◽  
Subramanian Raghunandakumar ◽  
Selvamani Asokkumar ◽  
John Binuclara ◽  
Balan Rajan ◽  
...  

2014 ◽  
Vol 4 (4) ◽  
pp. 535-541 ◽  
Author(s):  
R. Venugopal ◽  
V. Mahesh ◽  
G. Ekambaram ◽  
A. Aadithya ◽  
D. Sakthisekaran

Author(s):  
SATHESH KANNA VELLI ◽  
DEVAKI THIRUVENGADAM

Objective: The current plan was accompanied to explicate the possible protective role of vanillic acid (VA), on modification in lipid peroxidation, inflammatory cytokines, membrane-bound enzymes, and glycoconjugates during B(a)P induced lung cancer in Swiss albino mice. Methods: Benzo(a)pyrene was administered orally (50 mg/kg b. wt) to induce lung cancer in Swiss albino mice. lipid peroxidation, serum marker enzymes, inflammatory cytokines, membrane-bound ATPases and protein-bound carbohydrate components (Hexose, hexosamine, sialic acid and fucose) and Mast cells and PAS staining were carried out. Results: Lung cancer possessing animals exhibited increased levels of lipid peroxidation, ADA, AHH, γ-GT, 5’-NT, LDH, cytokines such as TNF-α and IL-1β, protein-bound carbohydrate components (protein-hexose, hexosamine, sialic acid, and fucose) also diminished activity of membrane-bound ATPases (Na+/K+ATPases, Ca2+ATPases, and Mg2+ATPase). Treatment with VA significantly ameliorated all these activities. Conclusion: Overall, the present study evidence to the VA has effective anti-inflammatory in addition to free radical scavenging activity for the duration of lung carcinogenesis in Swiss albino mice.


2004 ◽  
Vol 350 (1-2) ◽  
pp. 73-78 ◽  
Author(s):  
Karuppaiyah Selvendiran ◽  
Syed Mumtaz Banu ◽  
Dhanapal Sakthisekaran

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