Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21Cip1 and p27Kip1

Tsan-Zon Liu; Chung-Yi Chen; Shuenn-Jiun Yiin; Ching-Hsein Chen; Jiin-Tsuey Cheng; Ming-Kuei Shih; Yu-Shan Wang; Chi-Liang Chern

doi:10.1016/j.fct.2005.07.003

Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21Cip1 and p27Kip1

Food and Chemical Toxicology ◽

10.1016/j.fct.2005.07.003 ◽

2006 ◽

Vol 44 (2) ◽

pp. 227-235 ◽

Cited By ~ 40

Author(s):

Tsan-Zon Liu ◽

Chung-Yi Chen ◽

Shuenn-Jiun Yiin ◽

Ching-Hsein Chen ◽

Jiin-Tsuey Cheng ◽

...

Keyword(s):

Cell Cycle ◽

Protein Kinase ◽

Molecular Mechanism ◽

Mitogen Activated Protein Kinase ◽

Cdk Inhibitors ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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Faculty Opinions recommendation of Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009998.141066 ◽

2002 ◽

Author(s):

Guy Laurent

Keyword(s):

Cell Cycle ◽

Protein Kinase ◽

Cell Cycle Arrest ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Cycle Arrest ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

Permanent Cell

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Modulation of Mitogen-Activated Protein Kinase Activation and Cell Cycle Regulators by the Potent Skin Cancer Preventive Agent Silymarin

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1999.1398 ◽

1999 ◽

Vol 263 (2) ◽

pp. 528-536 ◽

Cited By ~ 43

Author(s):

Xiaolin Zi ◽

Rajesh Agarwal

Keyword(s):

Cell Cycle ◽

Protein Kinase ◽

Skin Cancer ◽

Mitogen Activated Protein Kinase ◽

Cell Cycle Regulators ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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1136-87 Remote preconditioning by infrarenal occlusion of the aorta protects the rat heart from infarction by a molecular mechanism involving free radicals and a p38 mitogen activated protein kinase activation

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(04)91250-8 ◽

2004 ◽

Vol 43 (5) ◽

pp. A295

Author(s):

Christof Weinbrenner ◽

Alexander Werschy ◽

Falk Schulze ◽

Ruth H Strasser

Keyword(s):

Free Radicals ◽

Protein Kinase ◽

Molecular Mechanism ◽

Rat Heart ◽

Mitogen Activated Protein Kinase ◽

Remote Preconditioning ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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Low concentrations of trichosanthin induce apoptosis and cell cycle arrest via c-Jun N-terminal protein kinase/mitogen-activated protein kinase activation

Molecular Medicine Reports ◽

10.3892/mmr.2014.2760 ◽

2014 ◽

Vol 11 (1) ◽

pp. 349-356 ◽

Cited By ~ 8

Author(s):

DUO ZHANG ◽

BIN CHEN ◽

JIAN ZHOU ◽

LIN ZHOU ◽

QING LI ◽

...

Keyword(s):

Cell Cycle ◽

Protein Kinase ◽

Cell Cycle Arrest ◽

Mitogen Activated Protein Kinase ◽

Terminal Protein ◽

Kinase Activation ◽

Cycle Arrest ◽

Protein Kinase Activation ◽

Low Concentrations ◽

Mitogen Activated Protein

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Faculty Opinions recommendation of Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1084943.537900 ◽

2007 ◽

Author(s):

Mark Hargreaves

Keyword(s):

Fatty Acids ◽

Protein Kinase ◽

Saturated Fatty Acids ◽

Mitogen Activated Protein Kinase ◽

Peroxisome Proliferator ◽

Pathogenic Role ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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Tibia tumor-induced cancer pain involves spinal p38 mitogen-activated protein kinase activation via TLR4-dependent mechanisms

Brain Research ◽

10.1016/j.brainres.2010.05.014 ◽

2010 ◽

Vol 1346 ◽

pp. 213-223 ◽

Cited By ~ 37

Author(s):

Silan Liu ◽

Jianping Yang ◽

Lina Wang ◽

Miao Jiang ◽

Qiaocheng Qiu ◽

...

Keyword(s):

Protein Kinase ◽

Cancer Pain ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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Positive Signaling Through CD72 Induces Mitogen-Activated Protein Kinase Activation and Synergizes with B Cell Receptor Signals to Induce X-Linked Immunodeficiency B Cell Proliferation

The Journal of Immunology ◽

10.4049/jimmunol.167.3.1263 ◽

2001 ◽

Vol 167 (3) ◽

pp. 1263-1273 ◽

Cited By ~ 27

Author(s):

Hsin-Jung Wu ◽

Chandrasekar Venkataraman ◽

Steven Estus ◽

Chen Dong ◽

Roger J. Davis ◽

...

Keyword(s):

Cell Proliferation ◽

Protein Kinase ◽

B Cell ◽

Cell Receptor ◽

B Cell Receptor ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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Reconstitution of p21ras-dependent and -independent mitogen-activated protein kinase activation in a cell-free system.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)80676-0 ◽

1993 ◽

Vol 268 (27) ◽

pp. 19935-19938

Author(s):

B VanRenterghem ◽

J.B. Gibbs ◽

J.L. Maller

Keyword(s):

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Free System ◽

Kinase Activation ◽

Cell Free System ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

A Cell

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Antimony-induced astrocyte activation via mitogen-activated protein kinase activation-dependent CREB phosphorylation

Toxicology Letters ◽

10.1016/j.toxlet.2021.09.006 ◽

2021 ◽

Author(s):

Yudan Zheng ◽

Wenjie Ding ◽

Tao Zhang ◽

Zixuan Zhao ◽

Rui Wang ◽

...

Keyword(s):

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Astrocyte Activation ◽

Creb Phosphorylation ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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Oncostatin M-Mediated Growth Inhibition of Human Glioblastoma Cells Does Not Depend on Stat3 or on Mitogen-Activated Protein Kinase Activation

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2000.0750973.x ◽

2002 ◽

Vol 75 (3) ◽

pp. 973-981 ◽

Cited By ~ 8

Author(s):

Hartmut Halfter ◽

Florian Stögbauer ◽

Matthias Friedrich ◽

Susanne Serve ◽

Hubert Serve ◽

...

Keyword(s):

Protein Kinase ◽

Growth Inhibition ◽

Oncostatin M ◽

Mitogen Activated Protein Kinase ◽

Glioblastoma Cells ◽

Human Glioblastoma ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein ◽

Human Glioblastoma Cells

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