Determining the safety of chromium tripicolinate for addition to foods as a nutrient supplement

2004 ◽  
Vol 42 (6) ◽  
pp. 1029-1042 ◽  
Author(s):  
T.O Berner ◽  
M.M Murphy ◽  
R Slesinski
2012 ◽  
Vol 82 (4) ◽  
pp. 260-266 ◽  
Author(s):  
Salah E. Gariballa ◽  
Sarah J. Forster ◽  
Hilary J. Powers

Background: Although a number of studies have reported raised total plasma homocysteine (tHcy) concentrations in free-living older people, there are no data on homocysteine response to a mixed nutrient supplement in older patients. A raised plasma homocysteine concentration in older patients is partly a reflection of their co-morbidity, including impaired renal function, and there is uncertainty about the extent to which dietary interventions can improve plasma tHcy. Aim: To determine the plasma tHcy response to dietary supplements during acute illness. Methods: Two-hundred and thirty-six hospitalized, acutely ill older patients, who were part of a randomized double-blind placebo-controlled trial, were assigned to receive a daily oral nutritional supplement drink containing 1.3 mg of vitamin B2, 1.4 mg of vitamin B6, 1.5 μg of B12, 200 μg of folic acid, or a placebo, for 6 weeks. Outcome measures were plasma tHcy concentration at baseline, 6 weeks, and 6 months. Results: The mean plasma tHcy concentration fell among patients given the supplements (mean difference 4.1 µmol/L [95 % C.I, 0.14 to 8.03), p = 0.043], but tHcy concentration increased between 6 weeks and 6 months, after patients stopped taking the supplements [mean difference -2.0 µmol/L (95 % C.I, -03.9 to -0.18), p = 0.033]. About 46 % of patients in the placebo group and 55 % of patients in the supplement group had hyperhomocysteinemia (>14 µmol/L) at baseline compared with 45 % and 29 % at the end of the treatment period. Conclusions: A mixed nutrient supplement containing physiological amounts of B vitamins significantly reduced plasma tHcy concentrations in older patients recovering from acute illness.


2021 ◽  
Vol 9 (5) ◽  
pp. 1053
Author(s):  
Gonzalo Martinez-Fernandez ◽  
Jinzhen Jiao ◽  
Jagadish Padmanabha ◽  
Stuart E. Denman ◽  
Christopher S. McSweeney

We have found one inadvertent error in our paper published in Microorganisms [...]


2014 ◽  
Vol 46 (8) ◽  
pp. 1483-1489 ◽  
Author(s):  
Alex Tsungyu Hung ◽  
Brian Joseph Leury ◽  
Matthew Allen Sabin ◽  
Cherie Louise Collins ◽  
Frank Rowland Dunshea

2018 ◽  
Vol Volume 11 ◽  
pp. 195-201 ◽  
Author(s):  
Flavia Addor ◽  
Juliana Cotta Vieira ◽  
Camila Abreu

2004 ◽  
Vol 08 (23) ◽  
pp. 1298-1302 ◽  
Author(s):  
Krutika Desai ◽  
Subramanian Sivakami

This article is about spirulina and how it can be used as a nutrient supplement, a therapeutic agent, trace metal supplement, antioxidant, pigments, enviroment protector and a source of enzymes.


2018 ◽  
Vol 39 (2_suppl) ◽  
pp. S60-S68 ◽  
Author(s):  
Seth Adu-Afarwuah

Background: This article summarizes a presentation given at the 2017 Dairy for Global Nutrition Conference in Boise, Idaho. Objective: To give an overview of the pattern of early growth faltering in developing countries and examine the implications of the iLiNS-DYAD randomized trial in Ghana. Methods: The pattern of growth faltering in developing countries was outlined. In Ghana, 1320 women ≤ 20 weeks of pregnancy were assigned to 20 g/d small-quantity lipid-based nutrient supplement (SQ-LNS; LNS group) or multiple micronutrients (MMNs) containing 22 and 18 vitamins and minerals, respectively, until 6 months postpartum, or iron and folic acid (IFA) until delivery, and thereafter placebo until 6 months postpartum. Infants in the LNS group were assigned to SQ-LNS from 6 to 18 months of age. Results: Mean anthropometric z-scores for infants in developing countries start below the World Health Organization standard at 1 month of age, and generally decline until about age of 24 months. In the Ghana trial, mean (SD) birth weight (g) was greater ( P = .044) for the LNS group (3030 [414]) than the IFA group (2945 [442]) but not the MMN group (3005 [435]). Among primiparous mothers, the LNS group had significantly greater mean birth length, weight, and head circumference than the IFA or MMN group. By 18 months of age, the mean length (95% confidence interval) for the LNS group was +0.6 (0.1-1.1) cm greater than for the IFA group and +0.6 (0.1-1.2) cm greater than for the MMN group. Conclusion: Pre- and post-natal SQ-LNS consumption may improve fetal and infant growth in similar populations.


2018 ◽  
Vol 83 (6) ◽  
pp. 1748-1756 ◽  
Author(s):  
Shashank Gaur ◽  
Emely C. Lopez ◽  
Ankur Ojha ◽  
Juan E. Andrade

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