Safety evaluation of ice-structuring protein (ISP) type III HPLC 12 preparation. Lack of genotoxicity and subchronic toxicity

2004 ◽  
Vol 42 (2) ◽  
pp. 321-333 ◽  
Author(s):  
T. Hall-Manning ◽  
M. Spurgeon ◽  
A.M. Wolfreys ◽  
A.P. Baldrick
Toxicon ◽  
2020 ◽  
Vol 176 ◽  
pp. 59-66
Author(s):  
Alicia Lagarto ◽  
Viviana Bueno ◽  
María R. Pérez ◽  
Caridad C. Rodríguez ◽  
Irania Guevara ◽  
...  

2014 ◽  
Vol 72 ◽  
pp. 30-39 ◽  
Author(s):  
K.B. Ravi ◽  
K.R. Raghunatha Reddy ◽  
J. Shankaranarayanan ◽  
Jayant V. Deshpande ◽  
Vijaya Juturu ◽  
...  

2015 ◽  
Vol 72 (3) ◽  
pp. 473-480 ◽  
Author(s):  
Jun-Won Yun ◽  
Jeong-Hwan Che ◽  
Euna Kwon ◽  
Yun-Soon Kim ◽  
Seung-Hyun Kim ◽  
...  

2021 ◽  
Vol 275 ◽  
pp. 114138
Author(s):  
Jin A Jung ◽  
Jung-Ho Noh ◽  
Min Seong Jang ◽  
Eun-Young Gu ◽  
Min-Kyung Cho ◽  
...  

2013 ◽  
Vol 2 (1) ◽  
pp. 15 ◽  
Author(s):  
Alicia Lagarto ◽  
Viviana Bueno ◽  
Nelson Merino ◽  
Janet Piloto ◽  
Odalys Valdes ◽  
...  

2019 ◽  
Vol 9 (2) ◽  
pp. 362-366
Author(s):  
Gaurav Saxena ◽  
Abhilasha Mittal ◽  
Abdul Wadood Siddiqui

Draceana cinnabari (Dracaenaceae) is traditionally used in the treatment of wounds, leucorrhea, fractures, and diarrhoea. Herein, we performed a pre-clinical safety evaluation of extract of Draceana  cinnabari resin on Spradgue Dawley rats. Toxicological codicil of the extract was carried out following OECD guidelines 423 and 407, with minor changes. DC resin methanol extract administered to the rats by oral gavage at 50, 500, 1500, and 2500 mg/kg body weight daily up to 28 days to male and female rats. Herbal extract could most likely be very much endured up to the dose 2000 mg/kg body weight and could be named Category 4. Oral toxicity studies confirm that Draceana  cinnabari has no therapy-related demise or toxic signs on rats. Therefore, the resin, ought to be suitably considered for additional research for its medicinal and therapeutic efficacy. Keywords: Dracaenaceae, DC extract, Resin, Acute toxicity, Sub Chronic Toxicity


2020 ◽  
Vol 185 ◽  
pp. 04011
Author(s):  
Benjiao Li ◽  
Song Li ◽  
Binrong Ma ◽  
Yong Jing ◽  
Zheming Zhang ◽  
...  

Selenium-enriched yeast has the physiological functions of improving immunity, anti-oxidation, liver protection, lipid-lowering and anti-cancer. Currently, it is widely used as an organic selenium supplement to prevent diseases of livestock and poultry and aquatic animals, and increase the rate of littering and egg production rate of poultry, reduce the mortality of fish and other aquatic animals, and promote the growth of livestock and poultry. This article reviews the acute toxicity, genotoxicity and subchronic toxicity of selenium-enriched yeast, in order to provide a reference for the safe application of selenium-enriched yeast.


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