Therapeutic gardens as a design approach for optimising the healing environment of patients with Alzheimer's disease and other dementias: A narrative review

EXPLORE ◽  
2019 ◽  
Vol 15 (5) ◽  
pp. 352-362 ◽  
Author(s):  
Patrick Chukwuemeke Uwajeh ◽  
Timothy Onosahwo Iyendo ◽  
Mukaddes Polay
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Narrative Review ◽  
Design Approach ◽  
Healing Environment ◽  
Therapeutic Gardens

Minimalistic Design Approach for Multi-Reactivity against Free Radicals and Metal-Free and Metal-Bound Amyloid-β Peptides: Redox-Based Substitutions of Benzene

2019 ◽  
Author(s):  
Mingeun Kim ◽  
Juhye Kang ◽  
Misun Lee ◽  
Jiyeon Han ◽  
Geewoo Nam ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Free Radicals ◽  
Amyloid Β ◽  
Design Strategy ◽  
Design Approach ◽  
Metal Free

We report a minimalistic redox-based design strategy for engineering compact molecules based on the simplest aromatic framework, benzene, with multi-reactivity against free radicals, metal-free amyloid-β, and metal-bound amyloid-β, implicated in the most common form of dementia, Alzheimer’s disease.

A narrative review on the potential of tomato and lycopene for the prevention of Alzheimer’s disease and other dementias

2021 ◽  
pp. 1-12
Author(s):  
Federica Ratto ◽  
Flaminia Franchini ◽  
Massimo Musicco ◽  
Giulia Caruso ◽  
Simona Gabriella Di Santo
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Narrative Review

Sleep-related behaviors in Alzheimer’s disease and dementia with Lewy bodies

2015 ◽  
Vol 26 (1) ◽  
Author(s):  
Alberto Raggi ◽  
Walter Neri ◽  
Raffaele Ferri
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Circadian Rhythm ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
The Elderly ◽  
Narrative Review ◽  
Clinical Approach ◽  
Prevalence Studies

AbstractPrevalence studies suggest that Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) are the most common dementing illnesses in the elderly. The aim of this narrative review was to provide data on sleep-related behaviors in AD and DLB. This paper contains arguments, with a clinical approach, on both circadian rhythm changes and dissociated states of wakefulness and sleep in these two conditions.

Narrative Review of Sensory Changes as a Biomarker for Alzheimer’s Disease

2020 ◽  
pp. 109980042094717 ◽  
Author(s):  
Raymond R. Romano ◽  
Michael A. Carter ◽  
Todd B. Monroe
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Pain Perception ◽  
Early Recognition ◽  
Empirical Studies ◽  
Normal Subjects ◽  
Narrative Review ◽  
Cognitively Normal ◽  
Disease Modifying Drugs ◽  
Evidenced Based

Early recognition of Alzheimer’s disease (AD) in the prodromal period has not been robust yet will be necessary if effective disease-modifying drugs are to be useful in preventing or delaying the condition. The objective of this narrative review was to describe the current, evidenced based understanding of alterations in sensory data as potential biomarkers for AD. Review of empirical studies that tested senses as biomarkers for AD and were published in English within the past 50 years was completed. Eighteen empirical studies were identified that met the strict criteria for inclusion, with 12 of these studies being related to the olfactory system. Two studies examined auditory, two examined vision, one examined proprioception, and one examined taste. Thus, only olfaction has been studied to any extent, leaving a clear gap in the literature for the use of other senses. A promising area of research has begun to be reported concerning differences in responses to pain stimuli in AD relative to cognitively normal subjects. Pain is not a single sense like the others but integrates several senses and may allow for use as an early biomarker for AD, as it integrates several brain areas and pathways. Unlike the other senses, simple devices can be used to measure changes in pain perception in cognitively normal adults with genetic predispositions for possible AD, making this potentially useful for clinicians in the future.

Physical Activity in Preventing Alzheimer’s Disease and Cognitive Decline: A Narrative Review

2017 ◽  
Vol 48 (1) ◽  
pp. 29-44 ◽  
Author(s):  
Stefano Brini ◽  
Hamid R. Sohrabi ◽  
Jeremiah J. Peiffer ◽  
Mira Karrasch ◽  
Heikki Hämäläinen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Narrative Review
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