Characterization of resistance to a recombinant hexameric Fas-ligand (APO010) in human cancer cell lines

2020 ◽  
Vol 87 ◽  
pp. 33-41.e4
Author(s):  
Haatisha Jandu ◽  
Annette Nielsen ◽  
Nils Brunner ◽  
Anker Hansen ◽  
Steen Knudsen ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Fas Ligand ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines

scholarly journals Characterization of 2,3,6,7,10,11-hexahydroxytriphenylene and its effects on cell viability in human cancer cell lines

2016 ◽  
Vol 94 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Karine P. Naidek ◽  
Cristiane R. Zuconelli ◽  
Otavio M. Cruz ◽  
Ronny Ribeiro ◽  
Sheila M.B. Winnischofer ◽  
...  
Keyword(s):  
Cell Viability ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Annexin V ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Paramagnetic Resonance ◽  
Human Cancer Cell Lines

We synthesized 2,3,6,7,10,11-hexahydroxytriphenylene (HHTP), characterized it by electrochemistry, spectroelectrochemistry, and electron paramagnetic resonance techniques, and evaluated its cytotoxicity to human cancer cell lines. The results revealed that HHTP has accessible higher-oxidation states, especially the tris-semiquinone monoradical. This species is stable and is formed after being stored for months. HHTP exhibited cytotoxic effects on 5 human cancer cell lines, including glioma and lung cancer cells. The cytotoxic effect was evaluated based on the decrease in cell viability, increases in the percentage of cells with fragmented DNA, and elevated numbers of annexin V–PI-positive cells after HHTP treatment.

scholarly journals Purification and Characterization of a Lectin from Arisaema tortuosum Schott Having in-vitro Anticancer Activity against Human Cancer Cell Lines

BMB Reports ◽  
2005 ◽  
Vol 38 (5) ◽  
pp. 526-532 ◽  
Author(s):  
Vikram Dhuna ◽  
Jagmohan Singh Bains ◽  
Sukhdev Singh Kamboj ◽  
Jatinder Singh ◽  
Shanmugavel ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Purification And Characterization ◽  
Human Cancer Cell Lines

scholarly journals α-Tetralonyl Glucosides from the Green Walnut Husks of Juglans mandshurica and Their Antiproliferative Effects

Planta Medica ◽  
2019 ◽  
Vol 85 (04) ◽  
pp. 335-339
Author(s):  
An-dong Wang ◽  
Chao-jie Xie ◽  
Yun-qiang Zhang ◽  
Mei-chen Li ◽  
Xia Wang ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
2D Nmr ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Juglans Mandshurica ◽  
Antiproliferative Effects ◽  
Human Cancer Cell Lines

AbstractTwo new α-tetralonyl glucosides, (4S)-4,5,8-trihydroxy-α-tetralone-5-O-β-D-glucopyranosyl(1 → 6)-β-D-glucopyranoside (1) and (4S)-4,8-dihydroxy-α-tetralone-4-O-β-D-glucopyranosyl(1 → 6)-β-D-glucopyranoside (2), together with eight known compounds (3 – 10) were isolated from the green walnut husks of Juglans mandshurica. The structural characterization of all compounds was performed by spectroscopic analyses, including 1D and 2D NMR and HR-ESI-MS experiments. The isolated compounds were assayed for their cytotoxicity against two human cancer cell lines, A549 and HeLa. Four compounds (7 – 10) exhibited inhibitory effects against two human cancer cell lines with GI50 values between 1.3 and 5.8 µM.

scholarly journals Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Hang Ruan ◽  
Yu Xiang ◽  
Junsuk Ko ◽  
Shengli Li ◽  
Ying Jing ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Circular Rnas ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Comprehensive Characterization

scholarly journals Characterization of MicroRNA Expression Levels and Their Biological Correlates in Human Cancer Cell Lines

2007 ◽  
Vol 67 (6) ◽  
pp. 2456-2468 ◽  
Author(s):  
Arti Gaur ◽  
David A. Jewell ◽  
Yu Liang ◽  
Dana Ridzon ◽  
Jason H. Moore ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Microrna Expression ◽  
Human Cancer Cell ◽  
Expression Levels ◽  
Human Cancer Cell Lines
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