The role of polycomb group proteins and KDM2B in leukemia

2016 ◽  
Vol 44 (9) ◽  
pp. S104-S105
Author(s):  
Vincent van den Boom ◽  
Bauke de Boer ◽  
Maia Elliott ◽  
Pierre-Olivier Angrand ◽  
Edo Vellenga ◽  
...  
Keyword(s):  
Polycomb Group ◽  
Polycomb Group Proteins

scholarly journals The role of Polycomb Group Proteins in Cell Cycle Regulation During Development

Cell Cycle ◽  
2006 ◽  
Vol 5 (11) ◽  
pp. 1189-1197 ◽  
Author(s):  
Anne-Marie Martinez ◽  
Giacomo Cavalli
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Regulation ◽  
Polycomb Group ◽  
Polycomb Group Proteins ◽  
Cycle Regulation

scholarly journals Role of Polycomb group proteins in the hepatic stem cell self-renewal

2009 ◽  
Vol 53 (4) ◽  
pp. 115-119
Author(s):  
Yasuharu Ueno ◽  
Takako Naito ◽  
Hideki Taniguchi
Keyword(s):  
Stem Cell ◽  
Polycomb Group ◽  
Polycomb Group Proteins ◽  
Self Renewal ◽  
Hepatic Stem Cell

Role of Polycomb Group Proteins in Stem Cell Self-Renewal and Cancer

2005 ◽  
Vol 24 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Jesús Gil ◽  
David Bernard ◽  
Gordon Peters
Keyword(s):  
Stem Cell ◽  
Polycomb Group ◽  
Polycomb Group Proteins ◽  
Self Renewal

Polycomb Group Repression Is Blocked by the Drosophila suppressor of Hairy-wing [su(Hw)] Insulator

Genetics ◽  
1998 ◽  
Vol 148 (1) ◽  
pp. 331-339
Author(s):  
Daniel R Mallin ◽  
Jane S Myung ◽  
J Scott Patton ◽  
Pamela K Geyer
Keyword(s):  
Reporter Genes ◽  
Polycomb Group ◽  
Polycomb Group Proteins ◽  
Binding Region ◽  
Position Effects ◽  
Response Element ◽  
Polycomb Group Genes ◽  
Chromosomal Position ◽  
Group Response

Abstract The suppressor of Hairy-wing [SU(HW)] binding region disrupts communication between a large number of enhancers and promoters and protects transgenes from chromosomal position effects. These properties classify the SU(HW) binding region as an insulator. While enhancers are blocked in a general manner, protection from repressors appears to be more variable. In these studies, we address whether repression resulting from the Polycomb group genes can be blocked by the SU(HW) binding region. The effects of this binding region on repression established by an Ultrabithorax Polycomb group Response Element were examined. A transposon carrying two reporter genes, the yellow and white genes, was used so that repression and insulation could be assayed simultaneously. We demonstrate that the SU(HW) binding region is effective at preventing Polycomb group repression. These studies suggest that one role of the su(Hw) protein may be to restrict the range of action of repressors, such as the Polycomb group proteins, throughout the euchromatic regions of the genome.

scholarly journals Role of Polycomb Group Proteins in the DNA Damage Response – A Reassessment

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e102968 ◽  
Author(s):  
Hollie Chandler ◽  
Harshil Patel ◽  
Richard Palermo ◽  
Sharon Brookes ◽  
Nik Matthews ◽  
...  
Keyword(s):  
Dna Damage ◽  
Dna Damage Response ◽  
Polycomb Group ◽  
Polycomb Group Proteins ◽  
Damage Response
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