Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk

2016 ◽  
Vol 44 (5) ◽  
pp. 358-362.e5 ◽  
Author(s):  
Joerg Schmohl ◽  
Donato Santovito ◽  
Thomas Guenther ◽  
Wishnu Sutanto ◽  
Tanja Kroell ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Leukemia Blast ◽  
Blast Cells

scholarly journals Expression of Thy-1 antigen (CDw90) on adult acute leukemia blast cells [letter]

Blood ◽  
1996 ◽  
Vol 87 (1) ◽  
pp. 413-414 ◽  
Author(s):  
L Campos ◽  
D Guyotat
Keyword(s):  
Acute Leukemia ◽  
Leukemia Blast ◽  
Blast Cells

Monoclonal antibodies to antigens on human neutrophils, activated T lymphocytes, and acute leukemia blast cells

1987 ◽  
Vol 103 (6) ◽  
pp. 808-811
Author(s):  
G. Yu. Miterev ◽  
G. F. Burova ◽  
M. S. Puzhitskaya ◽  
S. V. Danilevich ◽  
T. I. Bulycheva
Keyword(s):  
Monoclonal Antibodies ◽  
T Lymphocytes ◽  
Acute Leukemia ◽  
Human Neutrophils ◽  
Leukemia Blast ◽  
Activated T Lymphocytes ◽  
Blast Cells

Surface endoglin (CD105) expression on acute leukemia blast cells: an extensive flow cytometry study of 1002 patients

2018 ◽  
Vol 59 (9) ◽  
pp. 2242-2245 ◽  
Author(s):  
Vincenzo Cosimato ◽  
Giulia Scalia ◽  
Maddalena Raia ◽  
Laura Gentile ◽  
Vincenza Cerbone ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Acute Leukemia ◽  
Leukemia Blast ◽  
Flow Cytometry Study ◽  
Blast Cells ◽  
Extensive Flow

Expression of interleukins 1, 3, 6, stem cell factor and their receptors in acute leukemia blast cells and in normal peripheral lymphocytes and monocytes

2009 ◽  
Vol 50 (3) ◽  
pp. 141-148 ◽  
Author(s):  
Sergio Ferrari ◽  
Alexis Grande ◽  
Rossella Manfredini ◽  
Enrico Tagliafico ◽  
Patrizia Zucchini ◽  
...  
Keyword(s):  
Stem Cell ◽  
Acute Leukemia ◽  
Stem Cell Factor ◽  
Leukemia Blast ◽  
Peripheral Lymphocytes ◽  
Blast Cells

Binding of monoclonal anti-interleukin 2 antibody to nucleoli in acute leukemia blast cells

1992 ◽  
Vol 16 (6-7) ◽  
pp. 589-595
Author(s):  
Martin Schwonzen ◽  
Michael Pfreundschuh ◽  
Christoph Pohl ◽  
Annette Schuh ◽  
Bernd Lathan ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Interleukin 2 ◽  
Leukemia Blast ◽  
Blast Cells

scholarly journals Simultaneous or sequential expression of lymphoid and myeloid phenotypes in acute leukemia

Blood ◽  
1985 ◽  
Vol 65 (1) ◽  
pp. 142-148 ◽  
Author(s):  
PB Neame ◽  
P Soamboonsrup ◽  
G Browman ◽  
RD Barr ◽  
N Saeed ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Myeloid Leukemia ◽  
Chromosomal Abnormalities ◽  
Lymphoblastic Leukemia ◽  
Differentiation Markers ◽  
Lymphoid Leukemia ◽  
Chromosome Marker ◽  
Fab Classification ◽  
Blast Cells ◽  
French American British

Abstract Acute mixed myeloid-lymphoid leukemia is uncommon. We report four cases in which myeloid and lymphoid cell markers were observed simultaneously or sequentially when 94 patients with acute leukemia were phenotyped according to the French-American-British (FAB) classification system, with cytochemical stains, and with immunologically defined differentiation markers (identified by monoclonal antibodies and antiterminal deoxynucleotidyl transferase [TdT]). In one case, conversion from acute lymphoblastic leukemia to acute myeloid leukemia was noted (FAB L1, TdT+ to FAB M4, Auer rods, TdT-). In another patient, two distinct populations of myeloid and lymphoid blast cells were observed simultaneously (TdT-, LeuM1+/TdT+, LeuM1-). In two additional patients, acute leukemia was characterized by the expression of both lymphoid and myeloid markers on the same cell (TdT+/Leu M1+, B4+/Leu M1+ and greater than or equal to 70% TdT+, T11+, My9+). The Philadelphia (Ph1) chromosome was negative in all cases, though other chromosomal abnormalities were noted in three out of four cases. Malignant transformation of a pluripotential stem cell for both lymphoid and myeloid lineages, with or without the Ph1 chromosome marker, could explain the coexistence of distinct populations of lymphoblasts and myeloblasts in acute leukemia. Acute leukemia with a biphenotypic profile may reflect genome depression accompanying neoplasia.

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