Identification of HLA class I–restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis

2006 ◽  
Vol 34 (11) ◽  
pp. 1496-1504 ◽  
Author(s):  
Masahiro Kawahara ◽  
Toshiyuki Hori ◽  
Yasushi Matsubara ◽  
Katsuya Okawa ◽  
Takashi Uchiyama
Keyword(s):  
T Cell ◽  
Hla Class I ◽  
Mass Spectrometric ◽  
Mass Spectrometric Analysis ◽  
Class I ◽  
Leukemia Cells ◽  
Spectrometric Analysis ◽  
Cell Leukemia ◽  
Tumor Associated Antigens ◽  
Adult T Cell Leukemia

Lack of interleukin-4 mRNA expression in adult T-cell leukemia cells

2009 ◽  
Vol 52 (3) ◽  
pp. 191-192 ◽  
Author(s):  
N. Mori ◽  
F. Shirakawa ◽  
S. Murakami ◽  
S. Oda ◽  
S. Eto
Keyword(s):  
T Cell ◽  
Mrna Expression ◽  
Interleukin 4 ◽  
Leukemia Cells ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia

scholarly journals ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells

Retrovirology ◽  
2011 ◽  
Vol 8 (1) ◽  
pp. 19 ◽  
Author(s):  
Keita Hagiya ◽  
Jun-ichirou Yasunaga ◽  
Yorifumi Satou ◽  
Koichi Ohshima ◽  
Masao Matsuoka
Keyword(s):  
T Cell ◽  
Binding Protein ◽  
Leukemia Cells ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Factor Binding ◽  
Adult T Cell Leukemia ◽  
Bzip Factor

DNA aneuploidy of adult T-cell leukemia cells

1994 ◽  
Vol 18 (2) ◽  
pp. 79-84 ◽  
Author(s):  
Shimeru Kamihira ◽  
Sunao Atogami ◽  
Hisashi Sohda ◽  
Saburo Momita ◽  
Kazuhiro Toryia ◽  
...  
Keyword(s):  
T Cell ◽  
Leukemia Cells ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Dna Aneuploidy ◽  
Adult T Cell Leukemia

Frequent expression of interleukin-9 mRNA and infrequent involvement of interleukin-9 in proliferation of primary adult T-cell leukemia cells and HTLV-I infected T-cell lines

1997 ◽  
Vol 21 (3) ◽  
pp. 211-216 ◽  
Author(s):  
Kakushi Matsushita ◽  
Naomichi Arima ◽  
Hideo Ohtsubo ◽  
Hiroshi Fujiwara ◽  
Shiroh Hidaka ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Lines ◽  
Leukemia Cells ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
T Cell Lines ◽  
Interleukin 9

scholarly journals T Cell Receptor Vβ Staining Identifies the Malignant Clone in Adult T cell Leukemia and Reveals Killing of Leukemia Cells by Autologous CD8+ T cells

2016 ◽  
Vol 12 (11) ◽  
pp. e1006030 ◽  
Author(s):  
Aileen G. Rowan ◽  
Aviva Witkover ◽  
Anat Melamed ◽  
Yuetsu Tanaka ◽  
Lucy B. M. Cook ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Cd8 T Cells ◽  
Cell Receptor ◽  
Leukemia Cells ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
T Cell Receptor Vβ

scholarly journals Association of High Proliferation in Adult T-cell Leukemia Cells With Apoptosis, and Expression of p53 Protein in Acute Type ATL

2008 ◽  
Vol 48 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Jia Wang ◽  
Kazuhisa Hasui ◽  
Atae Utsunomiya ◽  
Xinshan Jia ◽  
Takami Matsuyama ◽  
...  
Keyword(s):  
T Cell ◽  
P53 Protein ◽  
Leukemia Cells ◽  
Acute Type ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia

scholarly journals Expression of TGF-beta gene in adult T cell leukemia

Blood ◽  
1988 ◽  
Vol 71 (1) ◽  
pp. 263-266 ◽  
Author(s):  
Y Niitsu ◽  
Y Urushizaki ◽  
Y Koshida ◽  
K Terui ◽  
K Mahara ◽  
...  
Keyword(s):  
T Cell ◽  
Conditioned Medium ◽  
Mononuclear Cells ◽  
Myelogenous Leukemia ◽  
Leukemia Cells ◽  
Tgf Beta ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Colony Stimulating Activity ◽  
Peripheral Mononuclear Cells

Abstract Peripheral mononuclear cells from adult T cell leukemia (ATL) patients were analyzed in comparison with other types of leukemia cells, for the expression of transforming growth factor-beta (TGF-beta) mRNA, for the presence of TGF-beta activity (colony stimulating activity for normal rat kidney fibroblasts [NRK]) in conditioned medium and for their susceptibility to exogenous TGF-beta. Highly elevated TGF-beta mRNA levels were observed in all five ATL cell samples tested; however, in three acute myelogenous leukemia (AML) samples, in one acute lymphatic leukemia (ALL), and one chronic myelogenous leukemia (CML), TGF-beta expression was relatively lower. In normal peripheral mononuclear cells TGF-beta mRNA was weakly detectable. Colony stimulating activity for NRK found in the conditioned medium from ATL cells as well as other leukemia cells correlated well with the levels of TGF-beta mRNA expression. In all three ATL samples tested, stimulation of 3H- thymidine uptake by purified TGF-beta from platelets was apparent. These results suggest that ATL cells are secreting active TGF-beta in a relatively high amount, as compared with other leukemia cells, and may proliferate in response to the factor via an autocrine manner. Furthermore, considering that TGF-beta stimulates bone resorption, we can speculate that the relatively high amount of TGF-beta in ATL cells contributes to the hypercalcemia frequently seen in ATL patients.

Presence of human B-lymphocyte antigens on adult T-cell leukemia cells

1980 ◽  
Vol 17 (2) ◽  
pp. 287-295 ◽  
Author(s):  
Toshio Hattori ◽  
Takashi Uchiyama ◽  
Kiyoshi Takatsuki ◽  
Haruto Uchino
Keyword(s):  
T Cell ◽  
B Lymphocyte ◽  
Leukemia Cells ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia ◽  
Lymphocyte Antigens
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