The injury of fine particulate matter from cooking oil fumes on umbilical cord blood vessels in vitro

2017 ◽  
Vol 49 ◽  
pp. 65-73 ◽  
Author(s):  
Lijuan Hou ◽  
Jian Zhang ◽  
Chao Zhang ◽  
Yachun Xu ◽  
Xiaoxia Zhu ◽  
...  
Keyword(s):  
Particulate Matter ◽  
Cord Blood ◽  
Blood Vessels ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Fine Particulate Matter ◽  
Cooking Oil ◽  
Cooking Oil Fumes ◽  
Fine Particulate

scholarly journals Influence of residential exposure to traffic-related fine particulate matter on umbilical cord blood cytokine levels

2019 ◽  
Vol 3 ◽  
pp. 274
Author(s):  
García-Serna A ◽  
Martin-Orozco E ◽  
Hernández-Caselles T ◽  
Cantero E ◽  
Muñoz-García M ◽  
...  
Keyword(s):  
Particulate Matter ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Fine Particulate Matter ◽  
Residential Exposure ◽  
Fine Particulate ◽  
Cytokine Levels

scholarly journals Histomorphometry of Umbilical Cord Blood Vessels in Preeclampsia

2010 ◽  
Vol 13 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Manuel V. Blanco ◽  
Hilda R. Vega ◽  
Rodolfo Giuliano ◽  
Daniel R. Grana ◽  
Francisco Azzato ◽  
...  
Keyword(s):  
Cord Blood ◽  
Blood Vessels ◽  
Umbilical Cord ◽  
Umbilical Cord Blood

In vitro clinical-grade generation of red blood cells from human umbilical cord blood CD34+ cells

Transfusion ◽  
2008 ◽  
Vol 48 (10) ◽  
pp. 2235-2245 ◽  
Author(s):  
Eun Jung Baek ◽  
Han-Soo Kim ◽  
Sinyoung Kim ◽  
Honglien Jin ◽  
Tae-Yeal Choi ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Blood Cells ◽  
Human Umbilical Cord Blood ◽  
Human Umbilical Cord ◽  
Clinical Grade ◽  
Cd34 Cells ◽  
Cord Blood Cd34

scholarly journals DNA methylation of insulin-like growth factor 2 and H19 cluster in cord blood and prenatal air pollution exposure to fine particulate matter

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Congrong Wang ◽  
Michelle Plusquin ◽  
Akram Ghantous ◽  
Zdenko Herceg ◽  
Rossella Alfano ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Particulate Matter ◽  
Growth Factor ◽  
Cord Blood ◽  
Gene Cluster ◽  
Methylation Level ◽  
Fine Particulate Matter ◽  
Methylation Status ◽  
Insulin Like Growth Factor ◽  
Fine Particulate

Abstract Background The IGF2 (insulin-like growth factor 2) and H19 gene cluster plays an important role during pregnancy as it promotes both foetal and placental growth. We investigated the association between cord blood DNA methylation status of the IGF2/H19 gene cluster and maternal fine particulate matter exposure during fetal life. To the best of our knowledge, this is the first study investigating the association between prenatal PM2.5 exposure and newborn DNA methylation of the IGF2/H19. Methods Cord blood DNA methylation status of IGF2/H19 cluster was measured in 189 mother-newborn pairs from the ENVIRONAGE birth cohort (Flanders, Belgium). We assessed the sex-specific association between residential PM2.5 exposure during pregnancy and the methylation level of CpG loci mapping to the IGF2/H19 cluster, and identified prenatal vulnerability by investigating susceptible time windows of exposure. We also addressed the biological functionality of DNA methylation level in the gene cluster. Results Prenatal PM2.5 exposure was found to have genetic region-specific significant association with IGF2 and H19 during specific gestational weeks. The association was found to be sex-specific in both gene regions. Functionality of the DNA methylation was annotated by the association to fetal growth and cellular pathways. Conclusions The results of our study provided evidence that prenatal PM2.5 exposure is associated with DNA methylation in newborns’ IGF2/H19. The consequences within the context of fetal development of future phenotyping should be addressed.

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