Biosynthesis of reduced graphene oxide nanosheets and their in vitro cytotoxicity against cardiac cell lines of Catla catla

2016 ◽  
Vol 48 ◽  
pp. 110-115 ◽  
Author(s):  
Fu-Yan Xing ◽  
Lin-Lin Guan ◽  
Yan-Long Li ◽  
Chun-Juan Jia
2017 ◽  
Vol 7 ◽  
pp. 184798041770279 ◽  
Author(s):  
Xin Zhu ◽  
Xiaolin Xu ◽  
Feng Liu ◽  
Jizhong Jin ◽  
Lintao Liu ◽  
...  

A simple and green approach for the synthesis of polyphenol-functionalized reduced graphene oxide nanosheets is demonstrated, using leaf extract of Citrullus colocynthis as a deoxygenating agent. The C. colocynthis polyphenols also play a significant role as a stabilizing agent, preventing agglomeration of reduced graphene oxide nanosheets. Cytotoxicity tests showed that the both graphene oxide and Citrullus colocynthis polyphenol-stabilized reduced graphene oxide were toxic to DU145 cells; the cytotoxicity was dose dependent. Hence, C. colocynthis–mediated reduced graphene oxide may be an ideal anticancer material for biological study applications.


Author(s):  
Sireesh Babu Maddinedi ◽  
Jegatheeswaran Sonamuthu ◽  
Serap SuzuK Yildiz ◽  
Guobin Han ◽  
Yurong Cai ◽  
...  

2021 ◽  
Vol 164 ◽  
pp. 105979
Author(s):  
Xin Gao ◽  
Hengwei Zhang ◽  
Erjun Guo ◽  
Fei Yao ◽  
Zengze Wang ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sajad Bahrami ◽  
Nafiseh Baheiraei ◽  
Mostafa Shahrezaee

AbstractA variety of bone-related diseases and injures and limitations of traditional regeneration methods require new tissue substitutes. Tissue engineering and regeneration combined with nanomedicine can provide different natural or synthetic and combined scaffolds with bone mimicking properties for implantation in the injured area. In this study, we synthesized collagen (Col) and reduced graphene oxide coated collagen (Col-rGO) scaffolds, and we evaluated their in vitro and in vivo effects on bone tissue repair. Col and Col-rGO scaffolds were synthesized by chemical crosslinking and freeze-drying methods. The surface topography, and the mechanical and chemical properties of scaffolds were characterized, showing three-dimensional (3D) porous scaffolds and successful coating of rGO on Col. The rGO coating enhanced the mechanical strength of Col-rGO scaffolds to a greater extent than Col scaffolds by 2.8 times. Furthermore, Col-rGO scaffolds confirmed that graphene addition induced no cytotoxic effects and enhanced the viability and proliferation of human bone marrow-derived mesenchymal stem cells (hBMSCs) with 3D adherence and expansion. Finally, scaffold implantation into rabbit cranial bone defects for 12 weeks showed increased bone formation, confirmed by Hematoxylin–Eosin (H&E) and alizarin red staining. Overall, the study showed that rGO coating improves Col scaffold properties and could be a promising implant for bone injuries.


Author(s):  
Junyu Chang ◽  
Xiaobo Zhang ◽  
Zhenming Wang ◽  
Chunsheng Li ◽  
Qi Hu ◽  
...  

Carbon Trends ◽  
2021 ◽  
pp. 100074
Author(s):  
Lerato L Mokoloko ◽  
Boitumelo J Matsoso ◽  
Roy P. Forbes ◽  
Dean H. Barrett ◽  
Beatriz D. Moreno ◽  
...  

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