Effects of high-speed railway noise on the synaptic ultrastructure and phosphorylated-CaMKII expression in the central nervous system of SD rats

2013 ◽  
Vol 35 (1) ◽  
pp. 93-99 ◽  
Author(s):  
Guoqing Di ◽  
Yue Zheng
2013 ◽  
Vol 26 (3) ◽  
pp. 263-273 ◽  
Author(s):  
Mariko NAGATANI ◽  
Kayoko KUDO ◽  
Seiki YAMAKAWA ◽  
Toko OHIRA ◽  
Yuko YAMAGUCHI ◽  
...  

2021 ◽  
Vol 100 (4) ◽  
pp. 358-364
Author(s):  
Nina P. Setko ◽  
Olesya M. Zhdanova ◽  
Andrey G. Setko

Introduction. The harmonious development of cognitive processes is a prerequisite for students’ successful mastering of the educational program. The aim of the study is to give a psychophysiological characteristic of the peculiarities of the formation of cognitive functions in senior students. Materials and methods. The study of the functional state of the central nervous system (CNS) by the process of variational chronoreflexometry was carried out in 300 senior pupils of the traditional general education school; the assessment of cognitive abilities and intellectual level development was evaluated by using computer tests. Results. Pupils of the 9th and 11th grades were shown to have no significant differences in the CNS functional indices. In contrast, the CNS functional level was 1.6-1.7 times lower than the physiological norm. The nervous reaction’s stability was 1.3 -1.4 times, the level of functionality of the formed functional system was 1.3 times. The decrease in the level of CNS functioning of the studied adolescents was due to the consumption of reserve functional capabilities of the central nervous system and the body as a whole for the formation of cognitive functions, as evidenced by the development of verbal and non-verbal thinking in students from the 9th to the 11th grade, high speed of thinking processes, voluntary attention and its stability. It was proved that the development of thinking contributed to the formation of voluntary attention, an increase in its stability, and the degree of concentration, confirmed by the established correlation of moderate strength between the accuracy index and the level of formation of various types of thinking (r = 0,4). Conclusion. The established features of students’ intellectual development during a three-year study can be taken into account when organizing the educational process in traditional educational institutions to increase the level of cognitive development and academic performance of students.


Author(s):  
Gladys Harrison

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.


Author(s):  
John L.Beggs ◽  
John D. Waggener ◽  
Wanda Miller ◽  
Jane Watkins

Studies using mesenteric and ear chamber preparations have shown that interendothelial junctions provide the route for neutrophil emigration during inflammation. The term emigration refers to the passage of white blood cells across the endothelium from the vascular lumen. Although the precise pathway of transendo- thelial emigration in the central nervous system (CNS) has not been resolved, the presence of different physiological and morphological (tight junctions) properties of CNS endothelium may dictate alternate emigration pathways.To study neutrophil emigration in the CNS, we induced meningitis in guinea pigs by intracisternal injection of E. coli bacteria.In this model, leptomeningeal inflammation is well developed by 3 hr. After 3 1/2 hr, animals were sacrificed by arterial perfusion with 3% phosphate buffered glutaraldehyde. Tissues from brain and spinal cord were post-fixed in 1% osmium tetroxide, dehydrated in alcohols and propylene oxide, and embedded in Epon. Thin serial sections were cut with diamond knives and examined in a Philips 300 electron microscope.


Author(s):  
Ezzatollah Keyhani

Acetylcholinesterase (EC 3.1.1.7) (ACHE) has been localized at cholinergic junctions both in the central nervous system and at the periphery and it functions in neurotransmission. ACHE was also found in other tissues without involvement in neurotransmission, but exhibiting the common property of transporting water and ions. This communication describes intracellular ACHE in mammalian bone marrow and its secretion into the extracellular medium.


Author(s):  
S.S. Spicer ◽  
B.A. Schulte

Generation of monoclonal antibodies (MAbs) against tissue antigens has yielded several (VC1.1, HNK- 1, L2, 4F4 and anti-leu 7) which recognize the unique sugar epitope, glucuronyl 3-sulfate (Glc A3- SO4). In the central nervous system, these MAbs have demonstrated Glc A3-SO4 at the surface of neurons in the cerebral cortex, the cerebellum, the retina and other widespread regions of the brain.Here we describe the distribution of Glc A3-SO4 in the peripheral nervous system as determined by immunostaining with a MAb (VC 1.1) developed against antigen in the cat visual cortex. Outside the central nervous system, immunoreactivity was observed only in peripheral terminals of selected sensory nerves conducting transduction signals for touch, hearing, balance and taste. On the glassy membrane of the sinus hair in murine nasal skin, just deep to the ringwurt, VC 1.1 delineated an intensely stained, plaque-like area (Fig. 1). This previously unrecognized structure of the nasal vibrissae presumably serves as a tactile end organ and to our knowledge is not demonstrable by means other than its selective immunopositivity with VC1.1 and its appearance as a densely fibrillar area in H&E stained sections.


2018 ◽  
Vol 23 (1) ◽  
pp. 10-13
Author(s):  
James B. Talmage ◽  
Jay Blaisdell

Abstract Injuries that affect the central nervous system (CNS) can be catastrophic because they involve the brain or spinal cord, and determining the underlying clinical cause of impairment is essential in using the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), in part because the AMA Guides addresses neurological impairment in several chapters. Unlike the musculoskeletal chapters, Chapter 13, The Central and Peripheral Nervous System, does not use grades, grade modifiers, and a net adjustment formula; rather the chapter uses an approach that is similar to that in prior editions of the AMA Guides. The following steps can be used to perform a CNS rating: 1) evaluate all four major categories of cerebral impairment, and choose the one that is most severe; 2) rate the single most severe cerebral impairment of the four major categories; 3) rate all other impairments that are due to neurogenic problems; and 4) combine the rating of the single most severe category of cerebral impairment with the ratings of all other impairments. Because some neurological dysfunctions are rated elsewhere in the AMA Guides, Sixth Edition, the evaluator may consult Table 13-1 to verify the appropriate chapter to use.


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