Effects of bifenthrin on sex differentiation in Japanese Medaka (Oryzias latipes)

2019 ◽  
Vol 177 ◽  
pp. 108564 ◽  
Author(s):  
Luísa Becker Bertotto ◽  
Richard Bruce ◽  
Shuying Li ◽  
Jaben Richards ◽  
Rafid Sikder ◽  
...  
Keyword(s):  
Sex Differentiation ◽  
Oryzias Latipes ◽  
Japanese Medaka

Bisphenol A induces a shift in sex differentiation gene expression with testis‐ova or sex reversal in Japanese medaka ( Oryzias latipes )

2020 ◽  
Vol 40 (6) ◽  
pp. 804-814 ◽  
Author(s):  
Yoshifumi Horie ◽  
Nobuhiko Kanazawa ◽  
Chiho Takahashi ◽  
Norihisa Tatarazako ◽  
Taisen Iguchi
Keyword(s):  
Gene Expression ◽  
Bisphenol A ◽  
Sex Differentiation ◽  
Oryzias Latipes ◽  
Sex Reversal ◽  
Japanese Medaka ◽  
Differentiation Gene

Effects of tributyltin on early life-stage, reproduction, and gonadal sex differentiation in Japanese medaka (Oryzias latipes)

Chemosphere ◽  
2018 ◽  
Vol 203 ◽  
pp. 418-425 ◽  
Author(s):  
Yoshifumi Horie ◽  
Takahiro Yamagishi ◽  
Yoko Shintaku ◽  
Taisen Iguchi ◽  
Norihisa Tatarazako
Keyword(s):  
Early Life ◽  
Sex Differentiation ◽  
Life Stage ◽  
Oryzias Latipes ◽  
Early Life Stage ◽  
Japanese Medaka

Use of the Japanese Medaka ( Oryzias latipes ) and Guppy ( Poecilia reticulata ) in Carcinogenesis Testing Under National Toxicology Program Protocols

2003 ◽  
Vol 31 (1) ◽  
pp. 88-91 ◽  
Author(s):  
William E. Hawkins ◽  
William W. Walker ◽  
John W. Fournie ◽  
C. Steve Manning ◽  
Rena M. Krol
Keyword(s):  
Poecilia Reticulata ◽  
Oryzias Latipes ◽  
Japanese Medaka ◽  
National Toxicology Program

scholarly journals Transcriptomic profiles of Japanese medaka (Oryzias latipes) in response to alkalinity stress

2012 ◽  
Vol 11 (3) ◽  
pp. 2200-2246 ◽  
Author(s):  
Z.L. Yao ◽  
H. Wang ◽  
L. Chen ◽  
K. Zhou ◽  
C.Q. Ying ◽  
...  
Keyword(s):  
Oryzias Latipes ◽  
Japanese Medaka

scholarly journals Müllerian Inhibiting Substance Is Required for Germ Cell Proliferation during Early Gonadal Differentiation in Medaka (Oryzias latipes)

Endocrinology ◽  
2007 ◽  
Vol 149 (4) ◽  
pp. 1813-1819 ◽  
Author(s):  
Eri Shiraishi ◽  
Norifumi Yoshinaga ◽  
Takeshi Miura ◽  
Hayato Yokoi ◽  
Yuko Wakamatsu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Germ Cell ◽  
Germ Cells ◽  
Sex Differentiation ◽  
Somatic Cells ◽  
Oryzias Latipes ◽  
Cell Number ◽  
Gonadal Differentiation ◽  
Loss Of Function ◽  
Germ Cell Proliferation

Müllerian inhibiting substance (MIS) is a glycoprotein belonging to the TGF-β superfamily. In mammals, MIS is responsible for the regression of Müllerian ducts in the male fetus. However, the role of MIS in gonadal sex differentiation of teleost fish, which have no Müllerian ducts, has yet to be clarified. In the present study, we examined the expression pattern of mis and mis type 2 receptor (misr2) mRNAs and the function of MIS signaling in early gonadal differentiation in medaka (teleost, Oryzias latipes). In situ hybridization showed that both mis and misr2 mRNAs were expressed in the somatic cells surrounding the germ cells of both sexes during early sex differentiation. Loss-of-function of either MIS or MIS type II receptor (MISRII) in medaka resulted in suppression of germ cell proliferation during sex differentiation. These results were supported by cell proliferation assay using 5-bromo-2′-deoxyuridine labeling analysis. Treatment of tissue fragments containing germ cells with recombinant eel MIS significantly induced germ cell proliferation in both sexes compared with the untreated control. On the other hand, culture of tissue fragments from the MIS- or MISRII-defective embryos inhibited proliferation of germ cells in both sexes. Moreover, treatment with recombinant eel MIS in the MIS-defective embryos dose-dependently increased germ cell number in both sexes, whereas in the MISRII-defective embryos, it did not permit proliferation of germ cells. These results suggest that in medaka, MIS indirectly stimulates germ cell proliferation through MISRII, expressed in the somatic cells immediately after they reach the gonadal primordium.

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