Air pollution and cytokine responsiveness in asthmatic and non-asthmatic children

2015 ◽  
Vol 138 ◽  
pp. 381-390 ◽  
Author(s):  
Claudia Klümper ◽  
Ursula Krämer ◽  
Irina Lehmann ◽  
Andrea von Berg ◽  
Dietrich Berdel ◽  
...  
Keyword(s):  
Air Pollution ◽  
Asthmatic Children ◽  
Cytokine Responsiveness

scholarly journals Respiratory function declines in children with asthma associated with chemical species of fine particulate matter (PM2.5) in Nagasaki, Japan

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Yoonhee Kim ◽  
Eun Ha Park ◽  
Chris Fook Sheng Ng ◽  
Yeonseung Chung ◽  
Kunio Hashimoto ◽  
...  
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Urban Areas ◽  
Chemical Species ◽  
Mixed Effects ◽  
Linear Mixed Effects Model ◽  
Linear Mixed Effects ◽  
Asthmatic Children ◽  
Transboundary Air Pollution ◽  
Children With Asthma

Abstract Background The differential effects of PM2.5 fractions on children’s lung function remain inconclusive. This study aimed to examine whether lung function in asthmatic children was associated with increased PM2.5 fractions in urban areas in Nagasaki prefecture, Japan, where the air pollution level is relatively low but influenced by transboundary air pollution. Methods We conducted a multiyear panel study of 73 asthmatic children (boys, 60.3%; mean age, 8.2 years) spanning spring 2014–2016 in two cities. We collected self-measured peak expiratory flow (PEF) twice a day and daily time-series data for PM2.5 total mass and its chemical species. We fitted a linear mixed effects model to examine short-term associations between PEF and PM2.5, adjusting for individual and time-varying confounders. A generalized linear mixed effects model was also used to estimate the association for worsening asthma defined by severe PEF decline. Back-trajectory and cluster analyses were used to investigate the long-range transboundary PM2.5 in the study areas. Results We found that morning PEFs were adversely associated with higher levels of sulfate (− 1.61 L/min; 95% CI: − 3.07, − 0.15) in Nagasaki city and organic carbon (OC) (− 1.02 L/min; 95% CI: − 1.94, − 0.09) in Isahaya city, per interquartile range (IQR) increase at lag1. In addition, we observed consistent findings for worsening asthma, with higher odds of severe PEF decline in the morning for sulfate (odds ratio (OR) = 2.31; 95% CI: 1.12, 4.77) and ammonium (OR = 1.73; 95% CI: 1.06, 2.84) in Nagasaki city and OC (OR = 1.51; 95% CI: 1.06, 2.15) in Isahaya city, per IQR increase at lag1. The significant chemical species were higher on days that could be largely attributed to the path of Northeast China origin (for sulfate and ammonium) or both the same path and local sources (for OC) than by other clusters. Conclusions This study provides evidence of the differential effects of PM2.5 fractions on lung function among asthmatic children in urban areas, where the Japanese national standards of air quality have been nearly met. Continuous efforts to promote mitigation actions and public awareness of hazardous transboundary air pollution are needed to protect susceptible children with asthma.

Emergency Room Visits of Asthmatic Children, Relation to Air Pollution, Weather, and Airborne Allergens

1998 ◽  
Vol 81 (6) ◽  
pp. 563-570 ◽  
Author(s):  
Ben Zion Garty ◽  
Evsey Kosman ◽  
Eli Ganor ◽  
Victor Berger ◽  
Limor Garty ◽  
...  
Keyword(s):  
Air Pollution ◽  
Emergency Room ◽  
Emergency Room Visits ◽  
Asthmatic Children ◽  
Airborne Allergens

Lung Function and Air Pollution Exposure in Asthmatic Children From Mexico City

Epidemiology ◽  
2006 ◽  
Vol 17 (Suppl) ◽  
pp. S232-S233
Author(s):  
A Barraza-Villarreal ◽  
L Hernandez-Cadena ◽  
C Escamilla ◽  
B E. Del Rio-Navarro ◽  
J J. Siemra-Monge ◽  
...  
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Mexico City ◽  
Asthmatic Children ◽  
Air Pollution Exposure ◽  
Pollution Exposure

Air Pollution, Traffic Exposure, and Respiratory Symptoms in Asthmatic Children Residing in Mexico City

Epidemiology ◽  
2007 ◽  
Vol 18 (Suppl) ◽  
pp. S209
Author(s):  
M Escamilla ◽  
A Barraza-Villarreal ◽  
L Hernandez-Cadena ◽  
M Ramirez-Aguilar ◽  
B Del-Río ◽  
...  
Keyword(s):  
Air Pollution ◽  
Mexico City ◽  
Respiratory Symptoms ◽  
Asthmatic Children ◽  
Traffic Exposure

Air Pollution and Respiratory Status in Asthmatic Children: Hints for a Locally Based Preventive Strategy. AIRE Study

2003 ◽  
Vol 19 (6) ◽  
pp. 567-576 ◽  
Author(s):  
Andrea Ranzi ◽  
Mariaelena Gambini ◽  
Andrea Spattini ◽  
Claudia Galassi ◽  
Daniela Sesti ◽  
...  
Keyword(s):  
Air Pollution ◽  
Preventive Strategy ◽  
Asthmatic Children ◽  
Respiratory Status

HETEROGENEOUS RESPONSE OF DAILY PULMONARY FUNCTION TO AIR POLLUTION AMONG ASTHMATIC CHILDREN, THAILAND

Epidemiology ◽  
2003 ◽  
Vol 14 (Supplement) ◽  
pp. S23
Author(s):  
W Ackplakorn ◽  
D Loomis ◽  
N Vichit-Vadakan ◽  
S Wongtim ◽  
P Vitayanon ◽  
...  
Keyword(s):  
Air Pollution ◽  
Pulmonary Function ◽  
Asthmatic Children

Malonaldehyde in Exhaled Breath and Air Pollution Exposure in Asthmatic Children Exposed

Epidemiology ◽  
2006 ◽  
Vol 17 (Suppl) ◽  
pp. S302
Author(s):  
I Romieu ◽  
A Barraza-Villarreal ◽  
C Escamilla ◽  
A C Olin ◽  
A Isacsson
Keyword(s):  
Air Pollution ◽  
Exhaled Breath ◽  
Asthmatic Children ◽  
Air Pollution Exposure ◽  
Pollution Exposure

scholarly journals High Rates of Abnormal Lung Function and Lower Airway Inflammation in Non-Asthmatic Children Residing Near Point Sources of Outdoor Air Pollution

2019 ◽  
Vol 143 (2) ◽  
pp. AB224
Author(s):  
Deborah A. Gentile ◽  
Jennifer P. Elliott ◽  
Nicole L. Sossong ◽  
Albert Presto ◽  
Erica L. Butler ◽  
...  
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Airway Inflammation ◽  
Point Sources ◽  
Lower Airway ◽  
Outdoor Air ◽  
Asthmatic Children ◽  
Outdoor Air Pollution
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