scholarly journals In utero exposure to perfluorooctanoate (PFOA) or perfluorooctane sulfonate (PFOS) did not increase body weight or intestinal tumorigenesis in multiple intestinal neoplasia (Min/+) mice

2014 ◽  
Vol 132 ◽  
pp. 251-263 ◽  
Author(s):  
Ha Thi Ngo ◽  
Ragna Bogen Hetland ◽  
Azemira Sabaredzovic ◽  
Line Småstuen Haug ◽  
Inger-Lise Steffensen
Keyword(s):  
Body Weight ◽  
Perfluorooctane Sulfonate ◽  
In Utero ◽  
In Utero Exposure ◽  
Increase Body Weight ◽  
Intestinal Tumorigenesis ◽  
Intestinal Neoplasia

scholarly journals The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet inMin/+Mice as Adults

2015 ◽  
Vol 2015 ◽  
pp. 1-25
Author(s):  
Ha Thi Ngo ◽  
Ragna Bogen Hetland ◽  
Inger-Lise Steffensen
Keyword(s):  
High Fat Diet ◽  
Tumor Development ◽  
Adult Life ◽  
Tolerance Test ◽  
In Utero ◽  
Negative Control ◽  
Wild Type ◽  
Intestinal Tumorigenesis ◽  
Intestinal Neoplasia ◽  
Small Intestinal

We studied how obesogenic conditions during various life periods affected obesity and intestinal tumorigenesis in adult C57BL/6J-Min(multiple intestinal neoplasia)/+ mice. The mice were given a 10% fat diet throughout life (negative control) or a 45% fat dietin utero, during nursing, during bothin uteroand nursing, during adult life, or during their whole life-span, and terminated at 11 weeks for tumorigenesis (Min/+) or 23 weeks for obesogenic effect (wild-type). Body weight at 11 weeks was increased after a 45% fat diet during nursing, during bothin uteroand nursing, and throughout life, but had normalized at 23 weeks. In the glucose tolerance test, the early exposure to a 45% fat dietin utero, during nursing, or during bothin uteroand nursing, did not affect blood glucose, whereas a 45% fat diet given to adults or throughout life did. However, a 45% fat diet during nursing or duringin uteroand nursing increased the number of small intestinal tumors. So did exposures to a 45% fat diet in adult life or throughout life, but without increasing the tumor numbers further. The intrauterine and nursing period is a window of susceptibility for dietary fat-induced obesity and intestinal tumor development.

Effects of In Utero Exposure to Perfluorooctane Sulfonate on Placental Functions

2020 ◽  
Vol 54 (24) ◽  
pp. 16050-16061
Author(s):  
Hin Ting Wan ◽  
Aman Yi-Man Wong ◽  
Shi Feng ◽  
Chris Kong-Chu Wong
Keyword(s):  
Perfluorooctane Sulfonate ◽  
In Utero ◽  
In Utero Exposure

509: In Utero Exposure to the UV Stabilizer Benzophenone-2 Causes Hypospadias in Mice

2006 ◽  
Vol 175 (4S) ◽  
pp. 165-165
Author(s):  
Michael H. Hsieh ◽  
Erin Cheasty ◽  
Emily J. Willingham ◽  
Benchun Liu ◽  
Laurence S. Baskin
Keyword(s):  
In Utero ◽  
In Utero Exposure

Effect of In-Utero Exposure to High Dose Diethylstilbestrol on Intervertebral Disk in Adult Male and Female Progeny

2012 ◽  
Vol 2 (1_suppl) ◽  
pp. s-0032-1319931-s-0032-1319931
Author(s):  
S. Al Rowas ◽  
R. Gawri ◽  
R. Haddad ◽  
A. Almaawi ◽  
L. E. Chalifour ◽  
...  
Keyword(s):  
Adult Male ◽  
In Utero ◽  
Intervertebral Disk ◽  
In Utero Exposure ◽  
High Dose ◽  
Female Progeny ◽  
Male And Female

In utero exposure to mainstream cigarette smoke alters neonatal pulmonary signaling networks and postnatal lung function

Pneumologie ◽  
2013 ◽  
Vol 67 (12) ◽  
Author(s):  
S Dehmel ◽  
P Nathan ◽  
K Milger ◽  
R Prungnaud ◽  
R Imker ◽  
...  
Keyword(s):  
Lung Function ◽  
Cigarette Smoke ◽  
In Utero ◽  
Signaling Networks ◽  
In Utero Exposure ◽  
Mainstream Cigarette Smoke

Peripheral Oxygenation In Term Neonates With In Utero Exposure To Smoking

2006 ◽  
Vol 210 (S 1) ◽  
Author(s):  
G Pichler ◽  
P Klaritsch ◽  
H Zotter ◽  
J Heinzinger ◽  
J Kutschera ◽  
...  
Keyword(s):  
In Utero ◽  
In Utero Exposure ◽  
Term Neonates

Peripheral Oxygenation In Term Neonates With In Utero Exposure To Smoking

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
G Pichler ◽  
P Klaritsch ◽  
H Zotter ◽  
J Heinzinger ◽  
J Kutschera ◽  
...  
Keyword(s):  
In Utero ◽  
In Utero Exposure ◽  
Term Neonates

IN UTERO EXPOSURE TO DIOXIN CAUSES NEOCORTICAL DYSGENESIS

2006 ◽  
Vol 37 (S 1) ◽  
Author(s):  
T Mitsuhashi ◽  
J Yonemoto ◽  
Y Kosuge ◽  
H Sone ◽  
K Kosaki ◽  
...  
Keyword(s):  
In Utero ◽  
In Utero Exposure
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