Acute exposure of zebrafish embryo (Danio rerio) to flutolanil reveals its developmental mechanism of toxicity via disrupting the thyroid system and metabolism

2018 ◽  
Vol 242 ◽  
pp. 1157-1165 ◽  
Author(s):  
Miaomiao Teng ◽  
Wentao Zhu ◽  
Dezhen Wang ◽  
Jin Yan ◽  
Suzhen Qi ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Zebrafish Embryo ◽  
Acute Exposure ◽  
Developmental Mechanism ◽  
Mechanism Of Toxicity

Acute exposure to ustiloxin A affects growth and development of early life zebrafish, Danio rerio

Chemosphere ◽  
2019 ◽  
Vol 226 ◽  
pp. 851-857 ◽  
Author(s):  
Zheng Hu ◽  
Yao Dang ◽  
Chunsheng Liu ◽  
Ligang Zhou ◽  
Hao Liu
Keyword(s):  
Danio Rerio ◽  
Early Life ◽  
Growth And Development ◽  
Acute Exposure

scholarly journals The emerging contaminant 3,3′-dichlorobiphenyl (PCB-11) impedes Ahr activation and Cyp1a activity to modify embryotoxicity of Ahr ligands in the zebrafish embryo model (Danio rerio)

2019 ◽  
Vol 254 ◽  
pp. 113027 ◽  
Author(s):  
Monika A. Roy ◽  
Karilyn E. Sant ◽  
Olivia L. Venezia ◽  
Alix B. Shipman ◽  
Stephen D. McCormick ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Zebrafish Embryo ◽  
Emerging Contaminant ◽  
Cyp1a Activity

scholarly journals Evaluation of acute toxicity of an aqueous extract of irradiated Labisia pumila on zebrafish embryo (Danio rerio)

2020 ◽  
Vol 23 (1and2) ◽  
pp. 42
Author(s):  
Santhra Segaran Balan ◽  
Punithaamalar Manokaram ◽  
Norshafarina Shari ◽  
Mahathir Mohd Uzid ◽  
Hasnah Bahari ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Aqueous Extract ◽  
Danio Rerio ◽  
Zebrafish Embryo ◽  
Labisia Pumila

Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper

Chemosphere ◽  
2020 ◽  
Vol 261 ◽  
pp. 127748 ◽  
Author(s):  
Dércia Santos ◽  
Luís Félix ◽  
Ana Luzio ◽  
Susana Parra ◽  
Edna Cabecinha ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Early Life ◽  
Acute Exposure ◽  
Life Stages ◽  
Early Life Stages ◽  
Toxicological Effects

Acute exposure to bis(2-ethylhexyl)phthalate disrupts calcium homeostasis, energy metabolism and induces oxidative stress in the testis of Danio rerio

Biochimie ◽  
2020 ◽  
Vol 175 ◽  
pp. 23-33 ◽  
Author(s):  
Hemily Batista-Silva ◽  
Betina Fernanda Dambrós ◽  
Keyla Rodrigues ◽  
Patrícia Acordi Cesconetto ◽  
Ariane Zamoner ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Energy Metabolism ◽  
Calcium Homeostasis ◽  
Danio Rerio ◽  
Acute Exposure ◽  
Ethylhexyl Phthalate

LETHAL CONCENTRATION 50% OF PATCHOULI OIL (Pogostemon cablin) TOWARDS ZEBRAFISH EMBRYO (Danio rerio)

2020 ◽  
Vol 3 (2) ◽  
pp. 1
Author(s):  
Romel Ciptoadi Wijaya
Keyword(s):  
Danio Rerio ◽  
Zebrafish Embryo ◽  
Toxicity Testing ◽  
Positive Control ◽  
Negative Control ◽  
Lethal Concentration ◽  
Zebrafish Embryos ◽  
Treatment Groups ◽  
Precise Prediction ◽  
Loss Of Appetite

Preface :Patchouli Oil requires toxicity testing for safety before we can use it widely. It causes side effects such as nausea, vomiting and loss of appetite in some people. Determination of lethal concentration 50% (LC50) in the early stages of zebrafish embryos development will provide an easier, faster and precise prediction of toxicity. At a certain dose, it can cause impairment and death toward organisms. Therefore, the aim of this study was to determine LC50 of Patchouli Oil in carboximethyl cellulose emulsifier towards zebrafish embryo (Danio rerio).Method :Laboratory experimental study was using zebrafish embryos at 2 hours post fertilization. The total of 160 embryos were used and divided into 8 groups, i.e.; Negative control (KN) was given the embryonic fluid, positive control 1 was given 5000 ppm of patchouli oil (KP1), positive control was given 5000 ppm of CMC (KP2), and 5 treatment groups, i.e.; concentration of 10 ppm (P1), 30 ppm (P2), 60 ppm (P3), 90 ppm (P4) and 120 ppm (P5) of Patchouli oil which was emulsified in CMC. The study was conducted with 3 times repetition. Data collection was done by calculating total of embryo’s deaths for each treatment at 24-72 hours of exposure. Data were analyzed using Regression Probit Analysis.Results :Mortality in the group of KN was 1.6%, KP1 was 98.3% and KP2 was 0%. Meanwhile in the treatment group of P1, P2, P3, P4 and P5 respectively were 0%, 5%, 10%, 25%, and 50%.Conclusion :Based on these results, Lethal Concentration 50% of Patchouli Oil in CMC emulsifier towards zebrafish embryo is 120 ppm.

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