Highly sensitive GQDs-MnO2 based assay with turn-on fluorescence for monitoring cerebrospinal acetylcholinesterase fluctuation: A biomarker for organophosphorus pesticides poisoning and management

2017 ◽  
Vol 224 ◽  
pp. 436-444 ◽  
Author(s):  
Jingjing Deng ◽  
Dingkun Lu ◽  
Xiaolei Zhang ◽  
Guoyue Shi ◽  
Tianshu Zhou
Keyword(s):  
Organophosphorus Pesticides ◽  
Turn On ◽  
Highly Sensitive

A phenanthrene[9,10-d]imidazole-phenol-based fluorescent probe combined ESIPT and AIE for “turn-on” detection of Cu2+ with a green-emitting and improved stokes shift and its application

2021 ◽  
Author(s):  
Jiahui Du ◽  
Bing Zhao ◽  
Wei Kan ◽  
Haochun Yin ◽  
Tianshu Song ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Fluorescent Sensors ◽  
Turn On ◽  
Highly Sensitive

Development of highly sensitive and selective fluorescent sensors toward Cu2+ has gained considerable attention in view of its application of environmental and biological fields. However, the strategy of sensing by...

A highly-sensitive “turn on” probe based on coumarin β-diketone for hydrazine detection in PBS and living cells

2021 ◽  
Vol 252 ◽  
pp. 119510
Author(s):  
Rui Chen ◽  
Guang-Jin Shi ◽  
Jia-Jia Wang ◽  
Hai-Feng Qin ◽  
Qi Zhang ◽  
...  
Keyword(s):  
Living Cells ◽  
Turn On ◽  
Highly Sensitive

A Highly Sensitive and Label-Free Microbead-Based ‘Turn-On’ Colorimetric Sensor for the Detection of Mercury(II) in Urine Using a Peroxidase-Like Split G-Quadruplex–Hemin DNAzyme

2018 ◽  
Vol 71 (12) ◽  
pp. 945
Author(s):  
Xin Fu ◽  
He Zhang ◽  
Jie Zhang ◽  
Shi-Tong Wen ◽  
Xing-Cheng Deng
Keyword(s):  
Standard Deviation ◽  
Base Pair ◽  
Limit Of Detection ◽  
Label Free ◽  
Turn On ◽  
Highly Sensitive ◽  
Relative Standard ◽  
G Quadruplex ◽  
Catalytically Active ◽  
Partial Cdna

A highly sensitive and label-free microbead-based ‘turn-on’ assay was developed for the detection of Hg2+ in urine based on the Hg2+-mediated formation of intermolecular split G-quadruplex–hemin DNAzymes. In the presence of Hg2+, T–T mismatches between the two partial cDNA strands were stabilized by a T–Hg2+–T base pair, and can cause the G-rich sequences of the two oligonucleotides to associate to form a split G-quadruplex which is able to bind hemin to form the catalytically active G-quadruplex–hemin DNAzyme. This microbead-based ‘turn-on’ process allows the detection of Hg2+ in urine samples at concentrations as low as 0.5 pM. The relative standard deviation and recovery are 1.2–3.9 and 98.7–103.2%, respectively. The remarkable sensitivity for Hg2+ is mainly attributed to the enhanced mass transport ability that is inherent in homogeneous microbead-based assays. Compared with previous developments of intermolecular split G-quardruplex–hemin DNAzymes for the homogeneous detection of Hg2+ (the limit of detection was 19nM), a signal enhancement of ~1000 times is obtained when such an assay is performed on the surface of microbeads.

A highly sensitive turn-on ratiometric luminescent probe based on postsynthetic modification of Tb3+@Cu-MOF for H2S detection

2017 ◽  
Vol 5 (38) ◽  
pp. 9943-9951 ◽  
Author(s):  
Xubin Zheng ◽  
Ruiqing Fan ◽  
Yang Song ◽  
Ani Wang ◽  
Kai Xing ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Luminescent Probe ◽  
Turn On ◽  
Postsynthetic Modification ◽  
Highly Sensitive ◽  
Sensitivity And Selectivity ◽  
H2s Detection

A novel probe, designed and prepared through PSM of Cu-MOFs and Tb3+ions, shows high sensitivity and selectivity for H2S.

Developing acetylcholinesterase-based inhibition assay by modulated synthesis of silver nanoparticles: applications for sensing of organophosphorus pesticides

RSC Advances ◽  
2015 ◽  
Vol 5 (76) ◽  
pp. 61998-62006 ◽  
Author(s):  
D. Nanda Kumar ◽  
A. Rajeshwari ◽  
S. A. Alex ◽  
M. Sahu ◽  
A. M. Raichur ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Organophosphorus Compounds ◽  
Organophosphorus Pesticides ◽  
Inhibition Assay ◽  
Highly Sensitive

A novel and highly sensitive probe for the detection of organophosphorus compounds (OPs) using acetylcholinesterase (AChE) and acetylthiocholine (ATCh) during the modulated synthesis of silver nanoparticles.

Sign in / Sign up

Export Citation Format

Share Document