Air pollution and blood lipid markers levels: Estimating short and long-term effects on elderly hypertension inpatients complicated with or without type 2 diabetes

2016 ◽  
Vol 215 ◽  
pp. 135-140 ◽  
Author(s):  
Sanhua Xiao ◽  
Ranran Liu ◽  
Youxiu Wei ◽  
Lin Feng ◽  
Xuemin Lv ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Air Pollution ◽  
Blood Lipid ◽  
Long Term Effects ◽  
Short And Long Term ◽  
Lipid Markers

Short and Long Term Effects of a DPP-4 Inhibitor Versus Bedtime NPH Insulin as ADD-ON Therapy in Patients with Type 2 Diabetes

2017 ◽  
Vol 22 (44) ◽  
pp. 6716-6721 ◽  
Author(s):  
Giordana Maluf da Silva ◽  
Katia Camarano Nogueira ◽  
Rosa Tsuneshiro Fukui ◽  
Marcia Regina Soares Correia ◽  
Rosa Ferreira dos Santos ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Long Term Effects ◽  
Nph Insulin ◽  
Short And Long Term

scholarly journals Short- and Long-Term Effects of Real-Time Continuous Glucose Monitoring in Patients With Type 2 Diabetes

Diabetes Care ◽  
2011 ◽  
Vol 35 (1) ◽  
pp. 32-38 ◽  
Author(s):  
R. A. Vigersky ◽  
S. J. Fonda ◽  
M. Chellappa ◽  
M. S. Walker ◽  
N. M. Ehrhardt
Keyword(s):  
Type 2 Diabetes ◽  
Real Time ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Long Term Effects ◽  
Short And Long Term

scholarly journals Immediate and Long-Term Effects of an 8-Week Digital Mental Health Intervention on Adults With Poorly Managed Type 2 Diabetes: Protocol for a Randomized Controlled Trial

10.2196/18578 ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. e18578
Author(s):  
Eliane Boucher ◽  
Judith T Moskowitz ◽  
Gina M Kackloudis ◽  
Julia L Stafford ◽  
Ian Kwok ◽  
...  
Keyword(s):  
Mental Health ◽  
Type 2 Diabetes ◽  
Controlled Trial ◽  
Long Term Effects ◽  
Randomized Controlled ◽  
Short And Long Term ◽  
Therapeutic Platform

Background Diabetes is a leading cause of years of life lost and accounts for approximately one-fourth of health care dollars spent in the United States. Many of these costs are related to poor medication adherence and lack of self-care behaviors and are thus preventable. Depression, which is more prevalent among people with diabetes than in the general population, predicts poorer management of one’s diabetes, whereas positive affect predicts engaging in more positive health behaviors. Consequently, interventions that improve depression and positive affect may also improve diabetes-related outcomes among people with diabetes. Although preliminary research on the impact of such interventions among people with diabetes is promising, these studies focused primarily on in-person interventions, have had small samples, and lack long-term follow-up. Objective This study aims to examine the short- and long-term effects of a digital therapeutic platform focused on mental health among adults with poorly managed type 2 diabetes and elevated levels of depression. Methods This is a randomized controlled trial in which adults with a type 2 diabetes diagnosis, elevated hemoglobin A1c (HbA1c) levels (≧7), and moderate to severe depressive symptoms will be randomly assigned to a positive emotion regulation skills intervention group or a sham digital intervention with only psychoeducational content. The study will take place over 14 months, including the 8-week intervention (or control) delivered via a digital therapeutic platform (Happify Health) and follow-up assessments at 3, 6, and 12 months postintervention. Throughout the intervention and for 1 week at each postintervention follow-up, participants will complete daily assessments of diabetes-related distress, diabetes regimen adherence, and mood. Our primary outcome, HbA1c, will be self-reported every 3 months throughout the study. Secondary and exploratory outcomes will be assessed at baseline; at 8 weeks; and at 3, 6, and 12 months postintervention. Results Recruitment is expected to begin in June 2020. Participants will begin the study as they are recruited and will finish in waves. The final wave of data collection from the 8-week intervention is expected for winter 2020, with the completion of the 12-month follow-up in winter 2021. Conclusions Although previous research suggests that in-person psychological interventions have promising effects on both psychological and physical outcomes among adults with diabetes, digital interventions can be advantageous because they are easily scalable and reduce many barriers that prevent people from seeking treatment. This trial will provide important information about the effects of a digital mental health intervention among adults with type 2 diabetes, assessing both short- and long-term effects of this intervention on HbA1c, depressive symptoms, and other diabetes-specific outcomes. If successful, this may introduce a scalable intervention that would help reduce some of the preventable costs associated with diabetes. Trial Registration ClinicalTrials.gov NCT04068805; https://clinicaltrials.gov/ct2/show/NCT04068805. International Registered Report Identifier (IRRID) PRR1-10.2196/18578

scholarly journals Immediate and Long-Term Effects of an 8-Week Digital Mental Health Intervention on Adults With Poorly Managed Type 2 Diabetes: Protocol for a Randomized Controlled Trial (Preprint)

2020 ◽  
Author(s):  
Eliane Boucher ◽  
Judith T Moskowitz ◽  
Gina M Kackloudis ◽  
Julia L Stafford ◽  
Ian Kwok ◽  
...  
Keyword(s):  
Mental Health ◽  
Type 2 Diabetes ◽  
Controlled Trial ◽  
Long Term Effects ◽  
Randomized Controlled ◽  
Short And Long Term ◽  
Therapeutic Platform

BACKGROUND Diabetes is a leading cause of years of life lost and accounts for approximately one-fourth of health care dollars spent in the United States. Many of these costs are related to poor medication adherence and lack of self-care behaviors and are thus preventable. Depression, which is more prevalent among people with diabetes than in the general population, predicts poorer management of one’s diabetes, whereas positive affect predicts engaging in more positive health behaviors. Consequently, interventions that improve depression and positive affect may also improve diabetes-related outcomes among people with diabetes. Although preliminary research on the impact of such interventions among people with diabetes is promising, these studies focused primarily on in-person interventions, have had small samples, and lack long-term follow-up. OBJECTIVE This study aims to examine the short- and long-term effects of a digital therapeutic platform focused on mental health among adults with poorly managed type 2 diabetes and elevated levels of depression. METHODS This is a randomized controlled trial in which adults with a type 2 diabetes diagnosis, elevated hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>) levels (≧7), and moderate to severe depressive symptoms will be randomly assigned to a positive emotion regulation skills intervention group or a sham digital intervention with only psychoeducational content. The study will take place over 14 months, including the 8-week intervention (or control) delivered via a digital therapeutic platform (Happify Health) and follow-up assessments at 3, 6, and 12 months postintervention. Throughout the intervention and for 1 week at each postintervention follow-up, participants will complete daily assessments of diabetes-related distress, diabetes regimen adherence, and mood. Our primary outcome, HbA<sub>1c</sub>, will be self-reported every 3 months throughout the study. Secondary and exploratory outcomes will be assessed at baseline; at 8 weeks; and at 3, 6, and 12 months postintervention. RESULTS Recruitment is expected to begin in June 2020. Participants will begin the study as they are recruited and will finish in waves. The final wave of data collection from the 8-week intervention is expected for winter 2020, with the completion of the 12-month follow-up in winter 2021. CONCLUSIONS Although previous research suggests that in-person psychological interventions have promising effects on both psychological and physical outcomes among adults with diabetes, digital interventions can be advantageous because they are easily scalable and reduce many barriers that prevent people from seeking treatment. This trial will provide important information about the effects of a digital mental health intervention among adults with type 2 diabetes, assessing both short- and long-term effects of this intervention on HbA1c, depressive symptoms, and other diabetes-specific outcomes. If successful, this may introduce a scalable intervention that would help reduce some of the preventable costs associated with diabetes. CLINICALTRIAL ClinicalTrials.gov NCT04068805; https://clinicaltrials.gov/ct2/show/NCT04068805. INTERNATIONAL REGISTERED REPORT PRR1-10.2196/18578

scholarly journals Short And Long-Term Cost-Effectiveness Of Starting Insulin Detemir In Insulin-Naïve People With Type-2 Diabetes

2013 ◽  
Vol 16 (3) ◽  
pp. A164
Author(s):  
P.D. Home ◽  
G.G. Gálvez ◽  
R. Malek ◽  
E. Hammerby ◽  
A. Nikolajsen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cost Effectiveness ◽  
Insulin Detemir ◽  
Short And Long Term

Long-Term Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Surgery on Type 2 Diabetes Mellitus in Morbidly Obese Subjects

2012 ◽  
Vol 256 (6) ◽  
pp. 1023-1029 ◽  
Author(s):  
Amanda Jiménez ◽  
Roser Casamitjana ◽  
Lílliam Flores ◽  
Judith Viaplana ◽  
Ricard Corcelles ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Morbidly Obese ◽  
Long Term Effects ◽  
Obese Subjects
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