Potential environmental factors that influence the nitrogen concentration and δ15N values in the moss Hypnum cupressiforme collected inside and outside canopy drip lines

2015 ◽  
Vol 198 ◽  
pp. 78-85 ◽  
Author(s):  
Mitja Skudnik ◽  
Zvonka Jeran ◽  
Franc Batič ◽  
Primož Simončič ◽  
Damijana Kastelec
Keyword(s):  
Environmental Factors ◽  
Nitrogen Concentration ◽  
Hypnum Cupressiforme ◽  
Canopy Drip

The effect of environmental conditions on extracellular protease activity in controlled fermentations of Aspergillus niger

Microbiology ◽  
2009 ◽  
Vol 155 (10) ◽  
pp. 3430-3439 ◽  
Author(s):  
Machtelt Braaksma ◽  
Age K. Smilde ◽  
Mariët J. van der Werf ◽  
Peter J. Punt
Keyword(s):  
Aspergillus Niger ◽  
Environmental Factors ◽  
Nitrogen Source ◽  
Protease Activity ◽  
Protein Production ◽  
Synergistic Effects ◽  
Nitrogen Concentration ◽  
Extracellular Protease ◽  
Culture Ph ◽  
Screening Experiments

Proteolytic degradation by host proteases is one of the key issues in the application of filamentous fungi for non-fungal protein production. In this study the influence of several environmental factors on the production of extracellular proteases of Aspergillus niger was investigated systematically in controlled batch cultures. Of all factors investigated in a series of initial screening experiments, culture pH and nitrogen concentration in particular strongly affected extracellular protease activities. For instance, at a culture pH of 4, protease activity was higher than at pH 5, and protease activity increased with increasing concentrations of ammonium as nitrogen source. Interestingly, an interdependence was observed for several of the factors studied. These possible interaction effects were investigated further using a full factorial experimental design. Amongst others, the results showed a clear interaction effect between nitrogen source and nitrogen concentration. Based on the observed interactions, the selection of environmental factors to reduce protease activity is not straightforward, as unexpected antagonistic or synergistic effects occur. Furthermore, not only were the effects of the process parameters on maximum protease activity investigated, but five other protease-related phenotypes were studied as well, such as maximum specific protease activity and maximum protease productivity. There were significant differences in the effect of the environmental parameters on the various protease-related phenotypes. For instance, pH significantly affected final levels of protease activity, but not protease productivity. The results obtained in this study are important for the optimization of A. niger for protein production.

Influence of canopy drip on the indicative N, S and δ15N content in moss Hypnum cupressiforme

2014 ◽  
Vol 190 ◽  
pp. 27-35 ◽  
Author(s):  
Mitja Skudnik ◽  
Zvonka Jeran ◽  
Franc Batič ◽  
Primož Simončič ◽  
Sonja Lojen ◽  
...  
Keyword(s):  
Hypnum Cupressiforme ◽  
Canopy Drip

Reductionist thinking and animal models in neuropsychiatric research

2019 ◽  
Vol 42 ◽  
Author(s):  
Nicole M. Baran
Keyword(s):  
Animal Models ◽  
Mental Disorders ◽  
Environmental Factors ◽  
Neuropsychiatric Disorders ◽  
Model Organisms ◽  
Developmental Genetic ◽  
Term Study ◽  
Genetic And Environmental Factors ◽  
Mechanisms Of Plasticity

AbstractReductionist thinking in neuroscience is manifest in the widespread use of animal models of neuropsychiatric disorders. Broader investigations of diverse behaviors in non-model organisms and longer-term study of the mechanisms of plasticity will yield fundamental insights into the neurobiological, developmental, genetic, and environmental factors contributing to the “massively multifactorial system networks” which go awry in mental disorders.

The dual nature of obesity in metabolic programming: quantity versus quality of adipose tissue

2020 ◽  
Vol 134 (18) ◽  
pp. 2447-2451
Author(s):  
Anissa Viveiros ◽  
Gavin Y. Oudit
Keyword(s):  
Adipose Tissue ◽  
Environmental Factors ◽  
Maternal Obesity ◽  
Metabolic Programming ◽  
Dual Nature ◽  
Prevalence Of Obesity ◽  
Adipose Tissue Volume ◽  
Males And Females ◽  
Metabolically Healthy

Abstract The global prevalence of obesity has been rising at an alarming rate, accompanied by an increase in both childhood and maternal obesity. The concept of metabolic programming is highly topical, and in this context, describes a predisposition of offspring of obese mothers to the development of obesity independent of environmental factors. Research published in this issue of Clinical Science conducted by Litzenburger and colleagues (Clin. Sci. (Lond.) (2020) 134, 921–939) have identified sex-dependent differences in metabolic programming and identify putative signaling pathways involved in the differential phenotype of adipose tissue between males and females. Delineating the distinction between metabolically healthy and unhealthy obesity is a topic of emerging interest, and the precise nature of adipocytes are key to pathogenesis, independent of adipose tissue volume.

Shared Responsibilities for Full Participation in Society: Planning Further Integration of the ICF Into AAC

2016 ◽  
Vol 1 (12) ◽  
pp. 83-93 ◽  
Author(s):  
Mary Blake Huer ◽  
Travis T. Threats
Keyword(s):  
Environmental Factors ◽  
Augmentative And Alternative Communication ◽  
Functional Limitations ◽  
Community Support ◽  
World Health ◽  
International Classification Of Functioning ◽  
Personal Factors ◽  
Social Service Agencies ◽  
Persons With Disabilities ◽  
Full Participation

The World Health Organization's (WHO's) 2001 International Classification of Functioning Disability and Health (ICF) has as one of its central tenets the full inclusion of persons with disabilities in society. It acknowledges the need for medical and rehabilitation intervention in its biopscychosocial framework. However, the WHO realizes that society must do its part to facilitate this full participation and empowerment. Persons with complex communication needs (PWCCN) often need augmentative and alternative communication (AAC) in order to express themselves. However, in order to access and successfully use AAC, PWCCN need access to the necessary AAC devices and services, as well as a willing society to interact with them as full contributing members of society. The factors outside of a person's specific physical and/or cognitive functional limitations are addressed in the ICF via the Personal and Environmental Factors. Personal Factors include the individual's personality traits, lifestyle, experiences, social/educational/professional background, race, gender, and age. Environmental Factors include community support systems, social service agencies, governments, social networks, and those persons that interact with the PWCCN. This article addresses the sociopolitical influences on PWCCN and their functioning from a human rights perspective. The necessary introspective role of speech-language pathologists in this process is explored.

377: Distribution of Smoking, Water Resource and Other Environmental Factors in Patients Affected by Superficial Bladder Cancer

2004 ◽  
Vol 171 (4S) ◽  
pp. 99-99
Author(s):  
Vincenzo Serretta ◽  
Vincenzo Altieri ◽  
Giuseppe Morgia ◽  
Rosalinda Allegro ◽  
Alessandra Di Lallo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Environmental Factors ◽  
Water Resource ◽  
Superficial Bladder Cancer
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