scholarly journals High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition

2019 ◽  
Vol 126 ◽  
pp. 377-386 ◽  
Author(s):  
Jun Wang ◽  
Daniel R. Hallinger ◽  
Ashley S. Murr ◽  
Angela R. Buckalew ◽  
Ryan R. Lougee ◽  
...  
Keyword(s):  
Phase Ii ◽  
High Throughput ◽  
High Throughput Screening ◽  
Sodium Iodide ◽  
Enrichment Analysis ◽  
Sodium Iodide Symporter

scholarly journals High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library

2018 ◽  
Vol 52 (9) ◽  
pp. 5417-5426 ◽  
Author(s):  
Jun Wang ◽  
Daniel R. Hallinger ◽  
Ashley S. Murr ◽  
Angela R. Buckalew ◽  
Steven O. Simmons ◽  
...  
Keyword(s):  
Phase I ◽  
High Throughput ◽  
High Throughput Screening ◽  
Sodium Iodide ◽  
Sodium Iodide Symporter ◽  
Chemical Library ◽  
Quantitative Chemical

scholarly journals MicroTape-A 384-Well Ultra High Throughput Screening System

1999 ◽  
Vol 4 (2) ◽  
pp. 31-34
Author(s):  
Thomas W. Astle
Keyword(s):  
Phase I ◽  
Unique Solution ◽  
Phase Ii ◽  
High Throughput ◽  
High Throughput Screening ◽  
Screening System ◽  
Well Pattern ◽  
Assay Automation

The use of a sprocket driven carrier tape provides a unique solution for Ultra High Throughput Screening. 10-microliter wells in the 384 well pattern are embossed in a polypropylene or polycarbonate carrier tape. For compound handling, 100,000 compounds in 5 microliter aliquots may be stored, sealed and frozen in a roll 16 inches in diameter and 4 inches wide. The sprocket drive provides recall to any given compound. At time of use, the peelable seal is removed for access to the compound aliquots. Two levels of assay automation are provided. In Phase I the compound MicroTape is used to support assays in the standard 384 well plate format. In Phase II the compounds are transferred directly to the assay MicroTape for Ultra High Throughput Screening at the rate of 100,000 per day.

High-throughput screening program for botanical extracts

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
L Hingorani ◽  
NP Seeram ◽  
B Ebersole
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Screening Program ◽  
Botanical Extracts

High throughput screening of microbial biodiversity for the discovery of novel cosmeceutical agents

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
K Georgousaki ◽  
N DePedro ◽  
AM Chinchilla ◽  
N Aliagiannis ◽  
F Vicente ◽  
...  
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Microbial Biodiversity

High throughput screening to investigate Brazilian Cerrado biome plant extract bank chemical diversity

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
LS Espindola ◽  
RG Dusi ◽  
KR Gustafson ◽  
J McMahon ◽  
JA Beutler
Keyword(s):  
High Throughput ◽  
Plant Extract ◽  
High Throughput Screening ◽  
Chemical Diversity ◽  
Brazilian Cerrado ◽  
Cerrado Biome

Identification of novel sodium iodide symporter (NIS) interactors which modulate iodide uptake

2016 ◽  
Author(s):  
Alice Fletcher ◽  
Vikki Poole ◽  
Bhavika Modasia ◽  
Waraporn Imruetaicharoenchoke ◽  
Rebecca Thompson ◽  
...  
Keyword(s):  
Sodium Iodide ◽  
Sodium Iodide Symporter ◽  
Iodide Uptake
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