scholarly journals Comments on “Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective”

2019 ◽  
Vol 122 ◽  
pp. 412-415 ◽  
Author(s):  
Edmond Sanganyado
Keyword(s):  
Human Health ◽  
Health Impacts ◽  
Future Perspective ◽  
Human Health Impacts ◽  
Chiral Pharmaceuticals ◽  
Potential Human Health

scholarly journals A case study of potential human health impacts from petroleum coke transfer facilities

2016 ◽  
Vol 66 (11) ◽  
pp. 1061-1076 ◽  
Author(s):  
Michael L. Dourson ◽  
Lyle R. Chinkin ◽  
David L. MacIntosh ◽  
Jennifer A. Finn ◽  
Kathleen W. Brown ◽  
...  
Keyword(s):  
Human Health ◽  
Petroleum Coke ◽  
Health Impacts ◽  
Human Health Impacts ◽  
Potential Human Health

scholarly journals Characterizing antibiotics in LCA—a review of current practices and proposed novel approaches for including resistance

2021 ◽  
Author(s):  
O. Nyberg ◽  
A. Rico ◽  
J. B. Guinée ◽  
P. J. G. Henriksson
Keyword(s):  
Human Health ◽  
Pathogenic Bacteria ◽  
Well Being ◽  
Antibiotic Use ◽  
Health Impacts ◽  
Indicator Approach ◽  
Human Health Impacts ◽  
Novel Approaches ◽  
Potential Human Health ◽  
Environmental Compartments

Abstract Purpose With antibiotic resistance (ABR) portrayed as an increasing burden to human health, this study reviews how and to what extent toxicological impacts from antibiotic use are included in LCAs and supplement this with two novel approaches to include ABR, a consequence of antibiotic use, into the LCA framework. Methods We review available LCA studies that deal with toxicological aspects of antibiotics to evaluate how these impacts from antibiotics have been characterized. Then, we present two novel approaches for including ABR-related impacts in life cycle impact assessments (LCIAs). The first approach characterizes the potential for ABR enrichment in the environmental compartment as a mid-point indicator, based on minimum selective concentrations for pathogenic bacteria. The second approach attributes human health impacts as an endpoint indictor, using quantitative relationships between the use of antibiotics and human well-being. Results and discussion Our findings show that no LCA study to date have accounted for impacts related to ABR. In response, we show that our novel mid-point indicator approach could address this by allowing ABR impacts to be characterized for environmental compartments. We also establish cause-effect pathways between antibiotic use, ABR, and human well-being that generate results which are comparable with USEtox and most endpoint impact assessment approaches for human toxicology. Conclusions Our proposed methods show that currently overlooked impacts from ABR enrichment in the environment could be captured within the LCA framework as a robust characterization methodology built around the established impact model USEtox. Substantial amounts of currently unavailable data are, however, needed to calculate emissions of antibiotics into the environment, to develop minimum selective concentrations for non-pathogenic bacteria, and to quantify potential human health impacts from AB use.

Investigating the potential human health impacts of coal seam gas development at a study site in the Surat Basin in southern Queensland

2020 ◽  
Vol 60 (2) ◽  
pp. 455
Author(s):  
Cameron R Huddlestone-Holmes ◽  
Siobhan Rigby ◽  
Sean Van Niekerk ◽  
Rachel Mackie ◽  
Andrea Walton
Keyword(s):  
Coal Seam ◽  
Human Health ◽  
Health Impacts ◽  
Coal Seam Gas ◽  
Potential Health ◽  
Diverse Range ◽  
Gas Treatment ◽  
Exposure Pathway ◽  
Human Health Impacts ◽  
Potential Human Health

This paper reports on an ongoing study of the potential human health impacts of coal seam gas (CSG) development at a study site in the Surat Basin in Queensland. This study follows the methodology established in GISERA’s human health effects of CSG activity study design project and focuses on potential physical (dust, noise, light) and chemical stressors. The study will focus on an area bounded by the Warrego Highway to north, between Chinchilla and Miles, extending south towards Tara. This area contains a diverse range of CSG activities involving two operators, over 2300 wells, 70 water storage ponds, four water treatment plants and over 20 gas treatment or compression stations. The area has a range of land uses with low to moderate population densities. These activities have been characterised to determine the physical and chemical stressors present and an exposure pathway assessment is being conducted to determine whether any of the stressors identified have a complete exposure pathway to humans. This assessment considers controls and other strategies already in place to mitigate and alleviate the impacts of stressors. The project involves a high degree of engagement with stakeholders, including the local community, industry and government, with the aim of ensuring the research is independent and trustworthy. The results of this research will assist government and industry in the regulation and conduct of CSG activities by providing an evidence base on potential health impacts, allowing the development of risk mitigation actions to reduce the potential for human health impacts, should any be identified.

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