Occurrence of organophosphorus flame retardants on skin wipes: Insight into human exposure from dermal absorption

2017 ◽  
Vol 98 ◽  
pp. 113-119 ◽  
Author(s):  
Xiaotu Liu ◽  
Gang Yu ◽  
Zhiguo Cao ◽  
Bin Wang ◽  
Jun Huang ◽  
...  
2018 ◽  
Vol 20 (5) ◽  
pp. 798-805 ◽  
Author(s):  
Nadeem Ali ◽  
Iqbal Mohammad Ibrahim Ismail ◽  
Mohammad W. Kadi ◽  
Hussain Mohammed Salem Ali Albar

Indoor settled dust particles are considered as an important source of human exposure to chemicals such as organophosphate flame retardants (PFRs).


2018 ◽  
Vol 237 ◽  
pp. 695-703 ◽  
Author(s):  
Joyce Cristale ◽  
Tiago Gomes Aragão Belé ◽  
Silvia Lacorte ◽  
Mary Rosa Rodrigues de Marchi

2012 ◽  
Vol 20 (2) ◽  
pp. 812-822 ◽  
Author(s):  
Joon-Woo Kim ◽  
Tomohiko Isobe ◽  
Agus Sudaryanto ◽  
Govindan Malarvannan ◽  
Kwang-Hyeon Chang ◽  
...  

Author(s):  
Zohra Chupeau ◽  
Nathalie Bonvallot ◽  
Fabien Mercier ◽  
Barbara Le Bot ◽  
Cecile Chevrier ◽  
...  

We aimed to identify high-priority organophosphorus flame retardants for action and research. We thus critically reviewed literature between 2000 and 2019 investigating organophosphorus flame retardants’ presence indoors and human exposure in Europe, as well as epidemiological evidence of human effects. The most concentrated compounds indoors were tris(2-butoxyethyl)phosphate (TBOEP), tris(1-chloro-2-propyl)phosphate (TCIPP), tris(2,3-dichloropropyl)phosphate (TDCIPP). TBOEP and TCIPP were the most consistently detected compounds in humans’ urine, hair or breast milk as well as tris (butyl) phosphate (TNBP) and tris (phenyl) phosphate (TPHP). Notably, epidemiological evidence concerned reprotoxicity, neurotoxicity, respiratory effects and eczema risk for TDCIPP, eczema increase for TBOEP, and neurodevelopmental outcomes for Isopropylated triarylphosphate isomers (ITPs). Given the ubiquitous presence indoors and the prevalence of exposure, the growing health concern seems justified. TDCIPP and TPHP seem to be of particular concern due to a high prevalence of exposure and epidemiological evidence. TBOEP and TNBP require epidemiological studies regarding outcomes other than respiratory or dermal ones.


2010 ◽  
Vol 18 (NA) ◽  
pp. 239-254 ◽  
Author(s):  
Adegbenro P. Daso ◽  
Olalekan S. Fatoki ◽  
James P. Odendaal ◽  
Jonathan O. Okonkwo

The presence of brominated flame retardants (BFRs) in various environmental matrices, including humans, has been well documented. Increasing levels of these emerging contaminants in various environmental compartments suggest the wide application of these chemicals in products of everyday use. The release of BFRs from treated products is generally believed to be the major source of these contaminants into the environment, particularly in indoor environments. The sources and pathways through which BFRs enter the human system are evaluated in this paper. Human exposure via consumption of contaminated food and water, inhalation and ingestion of dust, as well as dermal absorption, are important pathways for these contaminants. Consumption of fatty foods especially fish, meat, dairy products as well as human milk constitute important routes for human exposure to these contaminants. Although brominated diphenyl ether (BDE) 209 has been found to be less bioaccumulative due to its high molecular weight, its dominance in indoor dust samples could be responsible for its detection in most human tissues investigated. BDE 47 is the most dominant polybrominated diphenyl ether (PBDE) congener found in human tissues. Regional differences in BFR levels in various environmental and biological matrices reflect their consumption patterns with higher levels mostly reported in the North American environments than in other regions of the world.


2015 ◽  
Vol 196 ◽  
pp. 29-46 ◽  
Author(s):  
Gao-Ling Wei ◽  
Ding-Qiang Li ◽  
Mu-Ning Zhuo ◽  
Yi-Shan Liao ◽  
Zhen-Yue Xie ◽  
...  

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