Preparation of the molecularly imprinted polymers-based capacitive sensor specific for tegafur and its characterization by electrochemical impedance and piezoelectric quartz crystal microbalance

2004 ◽  
Vol 49 (24) ◽  
pp. 4101-4107 ◽  
Author(s):  
Haiping Liao ◽  
Zhaohui Zhang ◽  
Hui Li ◽  
Lihua Nie ◽  
Shouzhuo Yao
Keyword(s):  
Quartz Crystal Microbalance ◽  
Molecularly Imprinted Polymers ◽  
Quartz Crystal ◽  
Electrochemical Impedance ◽  
Capacitive Sensor ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Piezoelectric Quartz ◽  
Piezoelectric Quartz Crystal

Quartz Crystal Microbalance In-Line Sensing of Escherichia Coli in a Bioreactor Using Molecularly Imprinted Polymers

2014 ◽  
Vol 12 (6) ◽  
pp. 1152-1155 ◽  
Author(s):  
Renata Samardzic ◽  
Hermann F. Sussitz ◽  
Nathjanan Jongkon ◽  
Peter A. Lieberzeit
Keyword(s):  
Escherichia Coli ◽  
Quartz Crystal Microbalance ◽  
Molecularly Imprinted Polymers ◽  
Quartz Crystal ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

scholarly journals Rapid and Simultaneous Quantification of 4 Urinary Proteins by Piezoelectric Quartz Crystal Microbalance Immunosensor Array

2006 ◽  
Vol 52 (12) ◽  
pp. 2273-2280 ◽  
Author(s):  
Yang Luo ◽  
Ming Chen ◽  
Qianjun Wen ◽  
Meng Zhao ◽  
Bo Zhang ◽  
...  
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Clinical Chemistry ◽  
Label Free ◽  
Urinary Proteins ◽  
Quartz Crystals ◽  
Piezoelectric Quartz ◽  
Piezoelectric Immunosensor ◽  
Highly Sensitive ◽  
Piezoelectric Quartz Crystal

Abstract Background: Urinary proteins are predictive and prognostic markers for diabetes nephropathy. Conventional methods for the quantification of urinary proteins, however, are time-consuming, and most require radioactive labeling. We designed a label-free piezoelectric quartz crystal microbalance (QCM) immunosensor array to simultaneously quantify 4 urinary proteins. Methods: We constructed a 2 × 5 model piezoelectric immunosensor array fabricated with disposable quartz crystals for quantification of microalbumin, α1-microglobulin, β2-microglobulin, and IgG in urine. We made calibration curves after immobilization of antibodies at an optimal concentration and then evaluated the performance characteristics of the immunosensor with a series of tests. In addition, we measured 124 urine samples with both QCM immunosensor array and immunonephelometry to assess the correlation between the 2 methods. Results: With the QCM immunosensor array, we were able to quantify 4 urinary proteins within 15 min. This method had an analytical interval of 0.01–60 mg/L. The intraassay and interassay imprecisions (CVs) were <10%, and the relative recovery rates were 90.3%–109.1%. Nonspecificity of the immunosensor was insignificant (frequency shifts <20 Hz). ROC analyses indicated sensitivities were ≥95.8% and, specificities were ≥76.3%. Bland–Altman difference plots showed the immunosensor array to be highly comparable to immunonephelometry. Conclusions: The QCM system we designed has the advantages of being rapid, label free, and highly sensitive and thus can be a useful supplement to commercial assay methods in clinical chemistry.

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