Differentiation between graphene oxide and reduced graphene by electrochemical impedance spectroscopy (EIS)

2012 ◽  
Vol 20 ◽  
pp. 63-66 ◽  
Author(s):  
E. Casero ◽  
A.M. Parra-Alfambra ◽  
M.D. Petit-Domínguez ◽  
F. Pariente ◽  
E. Lorenzo ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Electrochemical Impedance Spectroscopy ◽  
Impedance Spectroscopy ◽  
Electrochemical Impedance ◽  
Reduced Graphene

scholarly journals A Novel Method for the Detection of SARS-CoV-2 Based on Graphene-Impedimetric Immunosensor

Materials ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4230
Author(s):  
Gabriel C. Zaccariotto ◽  
Martin K. L. Silva ◽  
Giovanna S. Rocha ◽  
Ivana Cesarino
Keyword(s):  
Cyclic Voltammetry ◽  
Graphene Oxide ◽  
Electrochemical Impedance Spectroscopy ◽  
Electrochemical Impedance ◽  
Rapid Diagnosis ◽  
Spike Protein ◽  
Electrochemical Immunoassay ◽  
Reduced Graphene ◽  
Novel Method ◽  
Impedimetric Immunosensor

Due to the SARS-CoV-2 pandemic, there has been an increase in the search for affordable healthcare devices for mass testing and rapid diagnosis. In this context, this work described a new methodology for SARS-CoV-2 detection based on an impedimetric immunosensor developed using the advantageous immobilization of antibodies in the reduced graphene oxide (rGO). The rGO was obtained by chemical synthesis from the commercial graphene oxide (GO), and the materials were morphologically, electrochemically and visually characterized. The cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques were used to evaluate the fabrication steps of the immunosensor. The electrochemical immunoassay was considered for SARS-CoV-2 spike protein RBD detection using a impedimetric immunosensor and redox couple ([(Fe(CN)6)]3−/4−) as a probe. The immunosensor was effectively developed and applied in the detection of SARS-CoV-2 spike protein RBD in saliva samples.

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