scholarly journals Flow Mediated Dilatation as a Biomarker for the Progression of Abdominal Aortic Aneurysms

2019 ◽  
Vol 58 (6) ◽  
pp. e57-e58
Author(s):  
Regent Lee ◽  
Kirthi Bellamkonda ◽  
Amy Jones ◽  
Nicholas Killough ◽  
Felicity Woodgate ◽  
...  
2020 ◽  
Author(s):  
Joel Ward ◽  
Xinghao Cheng ◽  
Yingyi Xiao ◽  
Pierfrancesco Lapolla ◽  
Anirudh Chandrashekar ◽  
...  

AbstractAbdominal aortic aneurysms (AAA) are associated with systemic inflammation and endothelial dysfunction. We previously reported flow mediated dilatation (FMD) of the brachial artery as a predictor of AAA growth. We hence hypothesised that other physical characteristics of the brachial artery correlate with AAA growth. Using a prospectively cohort of AAA patients, we devised a ‘brachial artery relaxation index’ (BARI) and examined its role as a biomarker for AAA growth. However, no correlation between BARI and future aneurysm growth was observed (p=0.5). Therefore, our investigations did not substantiate the hypothesis that other physical characteristics of the brachial artery predicts AAA growth.


PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248043
Author(s):  
Joel Ward ◽  
Xinghao Cheng ◽  
Yingyi Xiao ◽  
Pierfrancesco Lapolla ◽  
Anirudh Chandrashekar ◽  
...  

Abdominal aortic aneurysms (AAA) are associated with systemic inflammation and endothelial dysfunction. We previously reported flow mediated dilatation (FMD) of the brachial artery as a predictor of AAA growth. We hence hypothesised that other physical characteristics of the brachial artery correlate with AAA growth. Using a prospectively cohort of AAA patients, we devised a ‘brachial artery relaxation index’ (BARI) and examined its role as a biomarker for AAA growth. However, no correlation between BARI and future aneurysm growth was observed (p = 0.45). Therefore, our investigations did not substantiate the hypothesis that other physical characteristics of the brachial artery predicts AAA growth.


2017 ◽  
Vol 53 (6) ◽  
pp. 820-829 ◽  
Author(s):  
R. Lee ◽  
K. Bellamkonda ◽  
A. Jones ◽  
N. Killough ◽  
F. Woodgate ◽  
...  

2001 ◽  
Vol 71 (6) ◽  
pp. 341-344
Author(s):  
Johanna Rose ◽  
Ian Civil ◽  
Timothy Koelmeyer ◽  
David Haydock ◽  
Dave Adams

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 217-223 ◽  
Author(s):  
Diehm ◽  
Schmidli ◽  
Dai-Do ◽  
Baumgartner

Abdominal aortic aneurysm (AAA) is a potentially fatal condition with risk of rupture increasing as maximum AAA diameter increases. It is agreed upon that open surgical or endovascular treatment is indicated if maximum AAA diameter exceeds 5 to 5.5cm. Continuing aneurysmal degeneration of aortoiliac arteries accounts for significant morbidity, especially in patients undergoing endovascular AAA repair. Purpose of this review is to give an overview of the current evidence of medical treatment of AAA and describe prospects of potential pharmacological approaches towards prevention of aneurysmal degeneration of small AAAs and to highlight possible adjunctive medical treatment approaches after open surgical or endovascular AAA therapy.


VASA ◽  
2012 ◽  
Vol 41 (1) ◽  
pp. 3-4
Author(s):  
Diehm ◽  
Diehm ◽  
Dick

VASA ◽  
2019 ◽  
Vol 48 (1) ◽  
pp. 35-46
Author(s):  
Stephen Hofmeister ◽  
Matthew B. Thomas ◽  
Joseph Paulisin ◽  
Nicolas J. Mouawad

Abstract. The management of vascular emergencies is dependent on rapid identification and confirmation of the diagnosis with concurrent patient stabilization prior to immediate transfer to the operating suite. A variety of technological advances in diagnostic imaging as well as the advent of minimally invasive endovascular interventions have shifted the contemporary treatment algorithms of such pathologies. This review provides a comprehensive discussion on the current state and future trends in the management of ruptured abdominal aortic aneurysms as well as acute aortic dissections.


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