scholarly journals Aortic and Systemic Arterial Stiffness Responses to Acute Exercise in Patients With Small Abdominal Aortic Aneurysms

2019 ◽  
Vol 58 (5) ◽  
pp. 708-718
Author(s):  
Maria Perissiou ◽  
Tom G. Bailey ◽  
Mark Windsor ◽  
Kim Greaves ◽  
Michael C.Y. Nam ◽  
...  
2016 ◽  
Vol 50 (5) ◽  
pp. 317-320 ◽  
Author(s):  
Cleona Gray ◽  
Patrick Goodman ◽  
Stephen A. Badger ◽  
M. Kevin O’Malley ◽  
Martin K. O’Donohoe ◽  
...  

2012 ◽  
Vol 179 (1-3) ◽  
pp. 50-54 ◽  
Author(s):  
Nikolaos P.E. Kadoglou ◽  
Ioannis Papadakis ◽  
Konstantinos G. Moulakakis ◽  
Ignatios Ikonomidis ◽  
Maria Alepaki ◽  
...  

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
I Ikonomidis ◽  
P Rafouli-Stergiou ◽  
N Katsiki ◽  
N Kadoglou ◽  
S Vlachos ◽  
...  

Abstract Introduction Pulse wave velocity (PWV) is a valid, clinically feasible marker of arterial stiffening, and a strong predictor of outcomes. In patients with abdominal aortic aneurysms (AAA) alterations in arterial wall composition and inflammation were proposed as possible contributors to increased arterial stiffness. Purpose The present study aimed to compare aortic elastic properties in patients with abdominal aortic aneurysms (AAA), with or without coronary artery disease (CAD), as well as healthy individuals. Methods A total of 130 patients with AAA, eligible for interventional repair, and 30 healthy individuals, comprising the control group (HC), were evaluated. Study groups did not differ in anthropometrical characteristics and CV risk factors. Presence of CAD was identified by coronary angiography. Aortic PWV (aPWV) was measured using the Arteriograph method. Results aPWV was found considerably higher in AAA patients compared to HC group (11.5±2.9 vs. 7.3±1.6 m/s, p<0.001), after adjustment for age, sex and mean arterial pressure (MAP). Interestingly, among patients with AAA, those with concomitant CAD (n=41) had higher aPWV than those without CAD (12.5±2.9 vs. 11.0±3.0 m/s, p=0.03), after adjustment for age, sex and MAP. In receiver-operator-curve (ROC) analysis, the area under the curve (AUC) of aPWV for the prediction of CAD presence in the AAA study group was 0.72 [95% confidence interval (CI): 0.55–0.84, p=0.03]. According to this, the best cut-off was a value of aPWV above 12.8 m/s (78% sensitivity and 73% specificity). This cut-off was identified as a significant predictor of CAD presence in the AAA study population according to univariate logistic regression analysis (OR=2.51, 95% CI: 1.79–5.19, p=0.02). After adjustment for age, sex, dyslipidemia, smoking and MAP in multivariate logistic regression analysis, the cut-off aPWV level remained independently associated with the presence of CAD (OR=1.64, 95% CI: 1.19–4.08, p=0.03). Conclusion The co-existence of CAD and AAA is characterized by a greater arterial stiffness. This finding supports a role of measuring arterial stiffness markers when evaluating AAA patients' cardiovascular risk and selecting endovascular stents with more favorable elastic properties. Further studies are needed to explore whether aPWV values could be used to as a screening tool to detect CAD or to guide treatment in AAA patients. Funding Acknowledgement Type of funding source: None


2001 ◽  
Vol 71 (6) ◽  
pp. 341-344
Author(s):  
Johanna Rose ◽  
Ian Civil ◽  
Timothy Koelmeyer ◽  
David Haydock ◽  
Dave Adams

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 217-223 ◽  
Author(s):  
Diehm ◽  
Schmidli ◽  
Dai-Do ◽  
Baumgartner

Abdominal aortic aneurysm (AAA) is a potentially fatal condition with risk of rupture increasing as maximum AAA diameter increases. It is agreed upon that open surgical or endovascular treatment is indicated if maximum AAA diameter exceeds 5 to 5.5cm. Continuing aneurysmal degeneration of aortoiliac arteries accounts for significant morbidity, especially in patients undergoing endovascular AAA repair. Purpose of this review is to give an overview of the current evidence of medical treatment of AAA and describe prospects of potential pharmacological approaches towards prevention of aneurysmal degeneration of small AAAs and to highlight possible adjunctive medical treatment approaches after open surgical or endovascular AAA therapy.


VASA ◽  
2012 ◽  
Vol 41 (1) ◽  
pp. 3-4
Author(s):  
Diehm ◽  
Diehm ◽  
Dick

VASA ◽  
2019 ◽  
Vol 48 (1) ◽  
pp. 35-46
Author(s):  
Stephen Hofmeister ◽  
Matthew B. Thomas ◽  
Joseph Paulisin ◽  
Nicolas J. Mouawad

Abstract. The management of vascular emergencies is dependent on rapid identification and confirmation of the diagnosis with concurrent patient stabilization prior to immediate transfer to the operating suite. A variety of technological advances in diagnostic imaging as well as the advent of minimally invasive endovascular interventions have shifted the contemporary treatment algorithms of such pathologies. This review provides a comprehensive discussion on the current state and future trends in the management of ruptured abdominal aortic aneurysms as well as acute aortic dissections.


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