scholarly journals Predictors of Delayed Wound Healing after Endovascular Therapy of Isolated Infrapopliteal Lesions Underlying Critical Limb Ischemia in Patients with High Prevalence of Diabetes Mellitus and Hemodialysis

2015 ◽  
Vol 49 (5) ◽  
pp. 565-573 ◽  
Author(s):  
T. Shiraki ◽  
O. Iida ◽  
M. Takahara ◽  
Y. Soga ◽  
Y. Yamauchi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Delayed Wound Healing ◽  
High Prevalence ◽  
Prevalence Of Diabetes Mellitus

scholarly journals PREDICTORS OF DELAYED WOUND HEALING AFTER ENDOVASCULAR THERAPY IN PATIENTS WITH CRITICAL LIMB ISCHEMIA DUE TO ISOLATED INFRAPOPLITEAL LESIONS

2015 ◽  
Vol 65 (10) ◽  
pp. A2046
Author(s):  
Osamu Iida ◽  
Mitsuyoshi Takahara ◽  
Tatsuya Shiraki ◽  
Yoshimitsu Soga ◽  
Yasutaka Yamauchi ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Delayed Wound Healing

Abstract 14293: Time to Wound Healing and Major Adverse Limb Events in Patients With Critical Limb Ischemia Treated With Endovascular Therapy

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Grant W Reed ◽  
Negar Salehi ◽  
Pejman Raeisi-Giglou ◽  
Umair Malik ◽  
Rami Kafa ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Proportional Hazards ◽  
Limb Ischemia ◽  
Major Amputation ◽  
Cox Proportional Hazards ◽  
Time Dependent ◽  
Kaplan Meier

Introduction: There have been few studies evaluating the influence of time to wound healing on outcomes in patients with critical limb ischemia (CLI) after endovascular therapy. Methods: In this prospective study, patients with CLI treated with endovascular therapy were assessed for comorbidities, presence of wounds, wound healing, and major adverse limb events (MALE; major amputation, surgical endartectomy, or bypass) over time. The incidence of MALE was compared across patient and wound characteristics by Kaplan-Meier analysis. Associations between these variables and MALE were determined by Cox proportional hazards analysis. Results: A total of 252 consecutive patients with CLI were treated between November 1, 2011 and April 1, 2015; 179 (71%) had wounds, of which 97 (54%) healed. During median follow-up of 12.7 months (interquartile range 3.9 - 23.9 months), 46 (18%) had MALE. Wounds were associated with a greater risk of MALE (Hazard Ratio [HR] 3.5; 95% Confidence Interval [CI] 1.4-8.9; p=0.008). As a time-dependent covariate, wound healing was associated with less MALE (HR 0.23; 95% CI 0.10-0.53; p<0.001), and MALE was more frequent in patients with unhealed wounds (23% vs 11%; p<0.0001) (Figure - A). There was significantly less MALE in patients whose wounds healed within 4 months (24% vs 10%; p=0.032) (Figure - B), and less major amputation in those with healed wounds within 3 months (16% vs 5%; p=0.033). After multivariate adjustment for age, presence of diabetes, renal function, wound size, and procedural failure, independent predictors of MALE were wound healing as a time-dependent covariate (HR 0.18; 95% CI 0.08 - 0.40; p<0.0001), and creatinine ≥ 2 (HR 2.3; 95% CI 1.3-4.2; p=0.005). Conclusions: A shorter time to wound healing is associated with less MALE in patients with CLI after endovascular therapy. Efforts should be made to achieve wound healing as quickly as possible in this population, especially in those with renal dysfunction.

scholarly journals TCT-525 Wound depth assessed by Texas grade affect wound healing in critical limb ischemia after endovascular therapy

2014 ◽  
Vol 64 (11) ◽  
pp. B154
Author(s):  
Norihiro Kobayashi ◽  
Keisuke Hirano ◽  
Masatsugu Nakano ◽  
Toshiya Muramatsu ◽  
Reiko Tsukahara ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Limb Ischemia

Development and Validation of a New Scoring System to Predict Wound Healing After Endovascular Therapy in Critical Limb Ischemia With Tissue Loss

2015 ◽  
Vol 22 (1) ◽  
pp. 48-56 ◽  
Author(s):  
Norihiro Kobayashi ◽  
Keisuke Hirano ◽  
Masatsugu Nakano ◽  
Toshiya Muramatsu ◽  
Reiko Tsukahara ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Scoring System ◽  
Limb Ischemia ◽  
Tissue Loss ◽  
Development And Validation ◽  
New Scoring

scholarly journals Prognosis of critical limb ischemia patients with tissue loss after achievement of complete wound healing by endovascular therapy

2015 ◽  
Vol 61 (4) ◽  
pp. 951-959 ◽  
Author(s):  
Norihiro Kobayashi ◽  
Keisuke Hirano ◽  
Masatsugu Nakano ◽  
Yoshiaki Ito ◽  
Hiroshi Ishimori ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Tissue Loss ◽  
Complete Wound Healing

scholarly journals TCT-526 A New Scoring System for Predicting Wound Healing in Critical Limb Ischemia with Tissue Loss following Endovascular Therapy

2013 ◽  
Vol 62 (18) ◽  
pp. B159-B160
Author(s):  
Norihiro Kobayashi ◽  
Toshiya Muramatsu ◽  
Reiko Tsukahara ◽  
Yoshiaki Ito ◽  
Hiroshi Ishimori ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Scoring System ◽  
Limb Ischemia ◽  
Tissue Loss ◽  
New Scoring

scholarly journals TCT-527 What are the Predictors of Wound Healing in Patients with Critical Limb Ischemia with Tissue Loss following Successful Endovascular Therapy?

2013 ◽  
Vol 62 (18) ◽  
pp. B160
Author(s):  
Norihiro Kobayashi ◽  
Toshiya Muramatsu ◽  
Reiko Tsukahara ◽  
Yoshiaki Ito ◽  
Hiroshi Ishimori ◽  
...  
Keyword(s):  
Wound Healing ◽  
Endovascular Therapy ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Tissue Loss
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