A novel dressing for the combined delivery of platelet lysate and vancomycin hydrochloride to chronic skin ulcers: Hyaluronic acid particles in alginate matrices

2018 ◽  
Vol 118 ◽  
pp. 87-95 ◽  
Author(s):  
S. Rossi ◽  
M. Mori ◽  
B. Vigani ◽  
M.C. Bonferoni ◽  
G. Sandri ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Platelet Lysate ◽  
Vancomycin Hydrochloride ◽  
Skin Ulcers ◽  
Chronic Skin ◽  
Alginate Matrices

Calcium alginate particles for the combined delivery of platelet lysate and vancomycin hydrochloride in chronic skin ulcers

2014 ◽  
Vol 461 (1-2) ◽  
pp. 505-513 ◽  
Author(s):  
Michela Mori ◽  
Silvia Rossi ◽  
Maria Cristina Bonferoni ◽  
Franca Ferrari ◽  
Giuseppina Sandri ◽  
...  
Keyword(s):  
Calcium Alginate ◽  
Platelet Lysate ◽  
Vancomycin Hydrochloride ◽  
Skin Ulcers ◽  
Chronic Skin

Particulate systems based on pectin/chitosan association for the delivery of manuka honey components and platelet lysate in chronic skin ulcers

2016 ◽  
Vol 509 (1-2) ◽  
pp. 59-70 ◽  
Author(s):  
Marika Tenci ◽  
Silvia Rossi ◽  
Maria Cristina Bonferoni ◽  
Giuseppina Sandri ◽  
Cinzia Boselli ◽  
...  
Keyword(s):  
Platelet Lysate ◽  
Manuka Honey ◽  
Skin Ulcers ◽  
Chronic Skin ◽  
Particulate Systems

scholarly journals Il trattamento topico con una matrice contenente mesoglicano in associazione ad acido ialuronico nella gestione delle ulcere cutanee croniche degli arti inferiori/Topical treatment with a matrix containing mesoglycan in association with hyaluronic acid in the management of chronic skin ulcers of the lower limbs

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Rolando Tasinato ◽  
Paolo Zangrande
Keyword(s):  
Hyaluronic Acid ◽  
Povidone Iodine ◽  
Sono State ◽  
Lower Limbs ◽  
Iodine Solution ◽  
Skin Ulcers ◽  
Vascular Origin ◽  
Chronic Skin ◽  
Wound Bed Preparation ◽  
Povidone Iodine Solution

Un’ulcera cutanea cronica degli arti inferiori rappresenta l’epifenomeno di varie situazioni patologiche che possono coinvolgere, a vari livelli e con diversi gradi di interessamento, i sistemi venoso, arterioso e linfatico della gamba. Recentemente sono state pubblicate numerose evidenze secondo cui i glicosaminoglicani (GAG) svolgono un ruolo importante nella riepitelizzazione delle ulcere cutanee croniche degli arti inferiori, in particolare per quanto riguarda le ulcere ad eziopatogenesi vascolare venosa o mista. In questo articolo riportiamo la nostra esperienza nel trattamento delle ulcere cutanee croniche degli arti inferiori con una metodica che prevede il debridement secondo il protocollo TIME, antisepsi con una soluzione di iodopovidone al 10% la successiva l’applicazione di una medicazione bioattiva contenente GAG e acido ialuronico. Questa metodica è stata confrontata con un’analoga metodica che prevede sempre lo stesso tipo di debridement e di antisepsi con soluzione di iodopovidone al 10% affiancata a una medicazione non bioattiva. A chronic skin ulcer in the lower limbs represents the epiphenomenon of pathologies that may involve, at various levels, the venous, arterial, lymphatic and nervous systems of the leg, which must be identified and adequately treated. Recently, there has been increasing evidence that glycosaminoglycans (GAGs) play a role in the re-epithelialization of chronic skin ulcerative wounds of the lower limbs, particularly as regards ulcers of venous and arterial vascular origin. In this paper we report our experience in the treatment of chronic skin ulcers with debridement according to the TIME Wound Bed Preparation protocol with application of a bioactive dressing containing GAGs and hyaluronic acid, compared to a technique using a standard dressing involving the cleansing of the wound with 10% povidone iodine solution.

Sponge-Like Dressings Based on the Association of Chitosan and Sericin for the Treatment of Chronic Skin Ulcers. II. Loading of the Hemoderivative Platelet Lysate

2016 ◽  
Vol 105 (3) ◽  
pp. 1188-1195 ◽  
Author(s):  
Michela Mori ◽  
Silvia Rossi ◽  
Franca Ferrari ◽  
Maria C. Bonferoni ◽  
Giuseppina Sandri ◽  
...  
Keyword(s):  
Platelet Lysate ◽  
Skin Ulcers ◽  
Chronic Skin

Study to determine the efficacy of topical morphine on painful chronic skin ulcers

2005 ◽  
Vol 14 (6) ◽  
pp. 289-293 ◽  
Author(s):  
C. Vernassiere ◽  
C. Cornet ◽  
P. Trechot ◽  
F. Alla ◽  
F. Truchetet ◽  
...  
Keyword(s):  
Skin Ulcers ◽  
Chronic Skin

Collagenous Materials Enhance Healing of Chronic Skin Ulcers

1987 ◽  
Vol 110 ◽  
Author(s):  
Frederick H. Silver ◽  
Charles J. Doillon ◽  
Blas Rojo ◽  
Robert M. Olson ◽  
Chandrakala Y. Kamath ◽  
...  
Keyword(s):  
Type I Collagen ◽  
Systemic Infection ◽  
Collagen Sponge ◽  
Time Interval ◽  
Type I ◽  
Wound Area ◽  
Skin Ulcers ◽  
Chronic Skin ◽  
Observation Period

AbstractType I collagen in a porous sponge form attracts fibroblasts in culture and accelerates repair of animal wounds. This study examines the effect of type I collagen sponge and flakes on healing of chronic skin ulcers. Patients included in this study had skin ulcers.Patients included in this study had skin ulcers characterized by loss of dermis and epidermis without exposure of muscle, tendon or bone. Patients showing evidence of systemic infection or patients with ulcers that decreased in area during an initial three week observation period were excluded.Three out of seven patients treated with a collagen sponge and twelve out of fourteen patients treated with collagen flakes showed a 40% decrease in wound area after six weeks of treatment. In comparison, eighteen control patients showed no change in wound area over the same time interval. These results suggest that collagen flakes are effective in initiating healing of chronic skin ulcers.

scholarly journals Effects of laser therapy on chronic skin ulcers healing interventions for Sudanese patients

2015 ◽  
pp. 3720-3725
Author(s):  
Abdelrazig Abdelbagi ◽  
Masher Yousif ◽  
Shaza Yousif ◽  
Mahaseen Baloo
Keyword(s):  
Laser Therapy ◽  
Skin Ulcers ◽  
Chronic Skin
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