Semi-physiologically based pharmacokinetic modeling of paclitaxel metabolism and in silico-based study of the dynamic sensitivities in pathway kinetics

Martin N. Fransson; Jan Brugård; Peter Aronsson; Henrik Gréen

doi:10.1016/j.ejps.2012.08.002

Semi-physiologically based pharmacokinetic modeling of paclitaxel metabolism and in silico-based study of the dynamic sensitivities in pathway kinetics

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2012.08.002 ◽

2012 ◽

Vol 47 (4) ◽

pp. 759-767 ◽

Cited By ~ 2

Author(s):

Martin N. Fransson ◽

Jan Brugård ◽

Peter Aronsson ◽

Henrik Gréen

Keyword(s):

In Silico ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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In Silico Approaches for Physiologically Based Pharmacokinetic Modeling

Alternative Toxicological Methods ◽

10.1201/9780203008799.ch40 ◽

2003 ◽

Author(s):

Kannan Krishnan ◽

Martin B√©liveau

Keyword(s):

In Silico ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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In Silico Approaches for Physiologically Based Pharmacokinetic Modeling

Alternative Toxicological Methods ◽

10.1201/9780203008799-53 ◽

2003 ◽

pp. 503-556

Keyword(s):

In Silico ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Predicting Human Pharmacokinetics: Physiologically Based Pharmacokinetic Modeling and In Silico ADME Prediction in Early Drug Discovery

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/s13318-018-0503-9 ◽

2018 ◽

Vol 44 (1) ◽

pp. 135-137 ◽

Cited By ~ 2

Author(s):

Jian Shi ◽

Weibin Zha

Keyword(s):

Drug Discovery ◽

In Silico ◽

Pharmacokinetic Modeling ◽

Human Pharmacokinetics ◽

Physiologically Based Pharmacokinetic Modeling ◽

Adme Prediction ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

In Silico Adme Prediction ◽

Early Drug

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Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Exposure During Pregnancy

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Physiologically‐Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid‐to‐Lactone Conversion

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12447 ◽

2019 ◽

Vol 8 (9) ◽

pp. 664-675 ◽

Cited By ~ 5

Author(s):

Bridget L. Morse ◽

Jeffrey J. Alberts ◽

Maria M. Posada ◽

Jessica Rehmel ◽

Anil Kolur ◽

...

Keyword(s):

Gastric Emptying ◽

Delayed Gastric Emptying ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2243 ◽

2020 ◽

Vol 41 (6) ◽

pp. 248-267 ◽

Cited By ~ 1

Author(s):

Ling Song ◽

Zhiheng Yu ◽

Yifan Xu ◽

Xiaobei Li ◽

Xuanlin Liu ◽

...

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Prediction of fluoxetine and norfluoxetine pharmacokinetic profiles using physiologically based pharmacokinetic modeling

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1927 ◽

2021 ◽

Author(s):

Hyeon‐Cheol Jeong ◽

Yoon‐Jee Chae ◽

Sooyeun Lee ◽

Wonku Kang ◽

Hwi‐yeol Yun ◽

...

Keyword(s):

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Pharmacokinetic Profiles ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Cited By ~ 1

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling and Tissue Distribution Characteristics of SHetA2 in Tumor-Bearing Mice

The AAPS Journal ◽

10.1208/s12248-020-0421-z ◽

2020 ◽

Vol 22 (2) ◽

Author(s):

Ankur Sharma ◽

Mengjie Li ◽

Elangovan Thavathiru ◽

Mariam Ibrahim ◽

Lucila Garcia-Contreras ◽

...

Keyword(s):

Tissue Distribution ◽

Pharmacokinetic Modeling ◽

Distribution Characteristics ◽

Physiologically Based Pharmacokinetic Modeling ◽

Tumor Bearing ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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