Cellulose acetate butyrate–pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA

2007 ◽  
Vol 66 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Gheorghe Fundueanu ◽  
Marieta Constantin ◽  
Fabrizio Bortolotti ◽  
Rita Cortesi ◽  
Paolo Ascenzi ◽  
...  
Keyword(s):  
Oral Administration ◽  
Cellulose Acetate ◽  
Vinyl Alcohol ◽  
Cellulose Acetate Butyrate ◽  
Poly Vinyl Alcohol ◽  
Thermosensitive Polymer ◽  
Acetate Butyrate

Dielectric properties of amorphous cellulose acetate-butyrate polymer films

1993 ◽  
Vol 32 (4) ◽  
pp. 381-384 ◽  
Author(s):  
N. Venugopal Reddy ◽  
C. Ramesh Kumar ◽  
V. V. R. Narasimha Rao
Keyword(s):  
Dielectric Properties ◽  
Cellulose Acetate ◽  
Polymer Films ◽  
Cellulose Acetate Butyrate ◽  
Amorphous Cellulose ◽  
Acetate Butyrate

Cellulose acetate/poly(vinyl alcohol) hybrid fibrous mat containing tetracycline hydrochloride and phenytoin sodium: Morphology, drug release, antibacterial, and cell culture studies

2018 ◽  
Vol 33 (6) ◽  
pp. 597-611 ◽  
Author(s):  
Hamed Souriyan-Reyhani pour ◽  
Ramin Khajavi ◽  
Mohammad Esmaeil Yazdanshenas ◽  
Payam Zahedi ◽  
Mohammad Mirjalili
Keyword(s):  
Drug Release ◽  
Cellulose Acetate ◽  
Vinyl Alcohol ◽  
Aqueous Media ◽  
Tetracycline Hydrochloride ◽  
Diameter Distribution ◽  
Poly Vinyl Alcohol ◽  
Release Kinetic ◽  
Phenytoin Sodium ◽  
20 Nm

The objective of this study was to introduce an electrospun hybrid fibrous mat (a dual-fiber drug delivery system) based on cellulose acetate and poly(vinyl alcohol) containing tetracycline hydrochloride and phenytoin sodium, respectively. Characterization of samples was carried by morphology, drug release, cell cytotoxicity, adhesion, antibacterial property, and wettability investigations. The results showed a uniform shape and a narrow diameter distribution of fibers (between 160 ± 20 nm) for fabricated cellulose acetate/poly(vinyl alcohol) hybrid fibrous mat. The tetracycline hydrochloride release from cellulose acetate significantly decreased due to gel formation of poly(vinyl alcohol) in aqueous media. The best fit for drug release kinetic of hybrid sample was Higuchi model. Sample with tetracycline hydrochloride and phenytoin sodium drugs showed improved cell growth, viability, and antibacterial activity against Escherichia coli (~89%) and Staphylococcus aureus (~98%) in comparison with sample without drugs. The hydrophilic property of cellulose acetate/poly(vinyl alcohol) fibrous sample containing the drugs was also remarkable (~45°). To consider the obtained results, the presented hybrid fibrous mat shows a high potent for biomedical applications.

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