Change in symptom clusters in head and neck cancer patients undergoing postoperative radiotherapy: A longitudinal study

2018 ◽  
Vol 35 ◽  
pp. 62-66 ◽  
Author(s):  
S.H. Chiang ◽  
K.Y. Ho ◽  
S.Y. Wang ◽  
C.C. Lin
Keyword(s):  
Head And Neck Cancer ◽  
Longitudinal Study ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Postoperative Radiotherapy ◽  
Symptom Clusters

scholarly journals Analysis of Perioperative Platelet Indices and Their Prognostic Value in Head and Neck Cancer Patients Treated with Surgery and Postoperative Radiotherapy: A Retrospective Cohort Study

2019 ◽  
Vol 8 (11) ◽  
pp. 1858 ◽  
Author(s):  
Jank ◽  
Haas ◽  
Dunkler ◽  
Campion ◽  
Brkic ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Postoperative Radiotherapy ◽  
Prognostic Significance ◽  
Multivariable Analysis ◽  
Surrogate Marker ◽  
Platelet Indices ◽  
Kaplan Meier

Objectives: Activated platelets might play an important role in tumor progression. Mean platelet volume (MPV) has been used as a surrogate marker for platelet activation, and therefore its value as a marker of tumor prognosis has attracted recent attention. In this study, we aimed to critically evaluate the prognostic significance of the perioperative platelet count (COP), MPV and the MPV/COP ratio in head and neck cancer patients. Additionally, we explored the individual postoperative trajectory of these indices and their association with overall survival (OS) and disease-free survival (DFS). Methods: We retrospectively evaluated 122 head and neck squamous cell carcinoma patients receiving surgery with curative intent followed by postoperative radiotherapy. Platelet indices were measured preoperatively and on days 1 and 7 postoperatively. OS and DFS were analyzed using Kaplan–Meier estimators, the log-rank test and uni and multivariable Cox models. Cutoffs to dichotomize patients for Kaplan–Meier curves and log-rank tests were empirically chosen at the respective median. The median follow-up was 8.8 years. Results: The adjusted preoperative COP, MPV and MPV/COP ratio were not associated with disease outcome. A low postoperative COP and a high MPV/COP ratio on the first postoperative day were independently associated with worse OS and DFS. In comparison to the preoperative measurements, patients whose COP increased by day 1 post-op showed a better OS (hazard ratio (HR) per 50 G/L increase: 0.73, 95% confidence interval (CI): 0.58–0.93, p = 0.013) and DFS (HR per 50 G/L increase: 0.74, 95% CI: 0.58–0.94, p = 0.018) in multivariable analysis. Conclusions: Our results suggest that a low postoperative COP and a high MPV/COP ratio represent a negative prognostic factor for OS and DFS. Notably, patients with an increase in COP by day 1 post-op when compared to their preoperative value showed a significantly better OS and DFS.

Low-Level Laser for Mitigation of Low Salivary Flow Rate in Head and Neck Cancer Patients Undergoing Radiochemotherapy: A Prospective Longitudinal Study

2016 ◽  
Vol 34 (8) ◽  
pp. 326-330 ◽  
Author(s):  
Fernanda Aurora Stabile Gonnelli ◽  
Luiz Felipe Palma ◽  
Adelmo José Giordani ◽  
Aline Lima Silva Deboni ◽  
Rodrigo Souza Dias ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Longitudinal Study ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Flow Rate ◽  
Salivary Flow ◽  
Prospective Longitudinal Study ◽  
Level Laser ◽  
Prospective Longitudinal

scholarly journals Prevalence and Risk Factors of Suicidal Ideation in Head and Neck Cancer Patients: Longitudinal Study

2018 ◽  
Vol 56 (6) ◽  
pp. e53 ◽  
Author(s):  
Melissa Henry ◽  
Zeev Rosberger ◽  
Lia Bertrand ◽  
Christina Klassen ◽  
Michael Hier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Head And Neck Cancer ◽  
Longitudinal Study ◽  
Suicidal Ideation ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer

scholarly journals Decrease in Hemoglobin Levels Following Surgery Influences the Outcome in Head and Neck Cancer Patients Treated with Accelerated Postoperative Radiotherapy

2009 ◽  
Vol 16 (5) ◽  
pp. 1331-1336 ◽  
Author(s):  
Berrin Pehlivan ◽  
Abderrahim Zouhair ◽  
François Luthi ◽  
Luc Bron ◽  
Philippe Pasche ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Postoperative Radiotherapy
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