Effects of a psycho-educational programme on health-related quality of life in patients treated for colorectal and anal cancer: A feasibility trial

2016 ◽  
Vol 21 ◽  
pp. 181-188 ◽  
Author(s):  
Emma Ohlsson-Nevo ◽  
Jan Karlsson ◽  
Ulrica Nilsson
2019 ◽  
Vol 31 (2) ◽  
pp. 69-71 ◽  
Author(s):  
S.C. Sodergren ◽  
A. Gilbert ◽  
A.-S. Darlington ◽  
V. Vassiliou

2013 ◽  
Vol 52 (4) ◽  
pp. 736-744 ◽  
Author(s):  
Anne Gry Bentzen ◽  
Lise Balteskard ◽  
Eva Hoff Wanderås ◽  
Gunilla Frykholm ◽  
Tom Wilsgaard ◽  
...  

2018 ◽  
Vol 126 (2) ◽  
pp. 222-228 ◽  
Author(s):  
Samantha C. Sodergren ◽  
Colin D. Johnson ◽  
Alexandra Gilbert ◽  
Krzysztof A. Tomaszewski ◽  
William Chu ◽  
...  

2019 ◽  
Vol 34 (2) ◽  
pp. 205-219
Author(s):  
Joanne Bayly ◽  
Lucy Fettes ◽  
Eleanor Douglas ◽  
Maria J Teixiera ◽  
Nicola Peat ◽  
...  

Objectives: The main objective of this study is to determine the feasibility of recruiting and retaining patients recently diagnosed with thoracic cancer to a trial of short-term integrated rehabilitation; evaluate uptake of theoretically informed components targeting physical function, symptom self-management and participation; estimate sample size requirements for an efficacy trial. Design: Parallel group randomized controlled feasibility trial. Setting: Three U.K. hospitals. Participants: Patients ⩽eight weeks of thoracic cancer diagnosis, Eastern Cooperative Oncology Group Performance Status 0–3, any cancer stage and treatment plan. Interventions: Participants randomly allocated (1:1) to short-term integrated rehabilitation and standard care or standard care alone over 30 days. Main measures: Primary: participant recruitment and retention, targeting ⩾30% of eligible patients enrolling and ⩾50% of participants reporting outcomes at 30 days. Secondary: intervention fidelity; missing data and performance of outcome measures for self-efficacy, symptoms, physical activity and health-related quality of life. Results: Of 159 eligible patients approached, 54 (34%) were recruited. A total of 44 (82%) and 39 (72%) participants reported outcomes at 30 and 60 days, respectively. Intervention fidelity was high. Rehabilitation was delivered across 3 (1–3) sessions over 32 (22–45) days (median (range)). Changes in clinical outcomes were modest but most apparent at 60 days for health-related quality of life: Functional Assessment of Cancer Therapy Lung Cancer score median (interquartile range) change 9.7 (−12.0 to 16.0) rehabilitation versus 2.3 (−15.0 to 14.5) standard care. Conclusion: A trial to examine efficacy of short-term integrated rehabilitation for people newly diagnosed with thoracic cancer is feasible. A sample of 336 participants could detect a meaningful effect on health-related quality of life as the primary outcome.


2019 ◽  
Vol 74 (9) ◽  
pp. 1518-1525 ◽  
Author(s):  
Lauren A Beaupre ◽  
Jay S Magaziner ◽  
C Allyson Jones ◽  
Gian S Jhangri ◽  
D William C Johnston ◽  
...  

Abstract Background This study compared functional outcomes at 3 months after hip fracture surgery between nursing home residents participating in a 10-week outreach rehabilitation program and those receiving usual care. Function, health-related quality of life, and mortality were also compared over 12 months, and outreach program feasibility was assessed. Methods A feasibility trial was undertaken in Canadian nursing homes; of 77 participants, 46 were allocated to Outreach and 31 to Control prior to assessing function or cognition. Outreach participants received 10 weeks of rehabilitation (30 sessions), and Control participants received usual posthospital fracture care in their nursing homes. The primary outcome was the Functional Independence Measure Physical Domain (FIMphysical) score 3 months post-fracture; we also explored FIM Locomotion and Mobility. Secondary outcomes were FIM scores, EQ-5D-3L scores, and mortality over 12 months. Program feasibility was also evaluated. Results The mean age was 88.7 ± 7.0 years, 55 (71%) were female, and 58 (75%) had severe cognitive impairment with no significant group differences (p > .14). Outreach participants had significantly higher FIM Locomotion than usual care (p = .02), but no significant group differences were seen in FIMphysical or FIM Mobility score 3 months post-fracture. In adjusted analyses, Outreach participants reported significant improvements in all FIM and EQ-5D-3L scores compared with Control participants over 12 months (p < .05). Mortality did not differ by group (p = .80). Thirty (65%) Outreach participants completed the program. Conclusions Our feasibility trial demonstrated that Outreach participants achieved better locomotion by 3 months post-fracture compared with participants receiving usual postfracture care; benefits were sustained to 12 months post-fracture. In adjusted analyses, Outreach participants also showed sustained benefits in physical function and health-related quality of life.


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