Management of central venous catheters in pediatric onco-hematology using 0.9% sodium chloride and positive-pressure-valve needleless connector

2014 ◽  
Vol 18 (4) ◽  
pp. 393-396 ◽  
Author(s):  
Sara Buchini ◽  
Sara Scarsini ◽  
Marcella Montico ◽  
Roberto Buzzetti ◽  
Luca Ronfani ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Central Venous Catheters ◽  
Positive Pressure ◽  
Central Venous ◽  
Needleless Connector

scholarly journals Heparin versus 0.9% sodium chloride intermittent flushing for prevention of occlusion in central venous catheters in adults

2014 ◽  
Author(s):  
Eduardo López-Briz ◽  
Vicente Ruiz Garcia ◽  
Juan B Cabello ◽  
Sylvia Bort-Marti ◽  
Rafael Carbonell Sanchis ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Central Venous Catheters ◽  
Central Venous

Prospective, Randomized Trial of Two Different Modalities of Flushing Central Venous Catheters in Pediatric Patients With Cancer

2009 ◽  
Vol 27 (12) ◽  
pp. 2059-2065 ◽  
Author(s):  
Simone Cesaro ◽  
Gloria Tridello ◽  
Mara Cavaliere ◽  
Laura Magagna ◽  
Patrizia Gavin ◽  
...  
Keyword(s):  
Normal Saline ◽  
Complication Rate ◽  
Pediatric Patients ◽  
Central Venous Catheters ◽  
Positive Pressure ◽  
Cumulative Probability ◽  
Central Venous ◽  
Patients With Cancer ◽  
Heparin Solution ◽  
Premature Removal

Purpose There are limited prospective data on whether the method of flushing affects the complication rate of tunnelled central venous catheters (CVCs). Patients and Methods During a 25-month period, 203 pediatric patients who had newly placed Broviac-Hickman CVCs were randomly assigned to standard flushing with heparin solution or to experimental flushing with normal saline via a positive-pressure cap. Results Two hundred twenty-one complications were recorded among 75,249 CVC-days (2.94 per 1,000 CVC-days). A higher incidence of CVC occlusion (83 v 41 episodes; P = .0002) and bacteremia (24 v 9; P = .01) were found in the experimental arm. The cumulative probability of developing at least one CVC complication was higher in the experimental arm than in the standard arm (65.1% [95% CI, 55% to 75%] v 43.8% [95% CI, 34% to 54%], respectively; P = .01). No difference was found in either the cause or the frequency of premature removal of CVCs between the two study arms. After a median follow-up of 360 days (range, 4 to 1,073), CVC survival was similar: 77% (95% CI, 66% to 84%) for the experimental arm and 69% (95% CI, 53% to 80%) for the standard arm (P = .7). The factors associated with the occurrence of CVC complication were a diagnosis of leukemia/lymphoma, double-lumen CVC, and experimental flushing. The only factor significantly associated with premature removal of a CVC was a diagnosis of leukemia/lymphoma (hazard rate, 2.3; 95% CI, 1.1 to 4.7). Conclusion An increased complication rate was found with normal saline flushing, but additional investigation is warranted to clarify whether it is related to saline use or to once-a-week flushing.

scholarly journals Heparin versus 0.9% sodium chloride intermittent flushing for prevention of occlusion in central venous catheters in adults

2010 ◽  
Author(s):  
Eduardo López-Briz ◽  
Vicente Ruiz Garcia ◽  
Juan B Cabello ◽  
Sylvia Bort-Marti ◽  
Rafael Carbonell Sanchis ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Central Venous Catheters ◽  
Central Venous

scholarly journals Impact of Different Catheter Lock Strategies on Bacterial Colonization of Permanent Central Venous Hemodialysis Catheters

2013 ◽  
Vol 34 (12) ◽  
pp. 1314-1317 ◽  
Author(s):  
Stefan Erb ◽  
Andreas F. Widmer ◽  
Sarah Tschudin-Sutter ◽  
Ursula Neff ◽  
Manuela Fischer ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Bacterial Colonization ◽  
Hemodialysis Patients ◽  
Central Venous Catheters ◽  
Catheter Colonization ◽  
Central Venous ◽  
Lock Solution ◽  
Catheter Lock

Thirty-nine hemodialysis patients with permanent central venous catheters were analyzed for bacterial catheter colonization comparing different catheter-lock strategies. The closed needleless Tego connector with sodium chloride lock solution was significantly more frequently colonized with bacteria than the standard catheter caps with antimicrobially active citrate lock solution (odds ratio, 0.22 [95% confidence interval, 0.07–0.71]; P = .011).

The colonization rate of needleless connector and the impact of disinfection for 15 s on colonization: A prospective pre- and post-intervention study

2019 ◽  
Vol 20 (6) ◽  
pp. 604-607 ◽  
Author(s):  
İlker Devrim ◽  
Nevbahar Demiray ◽  
Yeliz Oruç ◽  
Kenan Sipahi ◽  
İlknur Çağlar ◽  
...  
Keyword(s):  
Isopropyl Alcohol ◽  
Intervention Study ◽  
External Surface ◽  
Central Venous Catheters ◽  
Central Venous ◽  
Post Intervention ◽  
Coagulase Negative Staphylococci ◽  
Two Samples ◽  
Needleless Connector ◽  
The Impact

Purpose: The optimal scrubbing time for the disinfection of the surface of needleless connectors has not been determined. The evidence for successful needleless connector decontamination with 70% isopropyl alcohol ranges from 5 to 60 s. The aim of this prospective study was to identify colonization on the external surface of needleless connectors on central venous catheters and measure the efficiency of 15 s of scrubbing with 70% alcohol. Method: A total of 31 patients were included. Samples were collected adhering to aseptic no-touch technique policies. Two samples were collected from the injectable surface of the needleless connector with sterile sodium chloride 0.9% moistened and a dry swab from the same site. Then the surface was scrubbed with alcohol 70% for 15 s for disinfection and second couples of samples for the cultures were taken after disinfection. Findings: A total of 420 swabs were obtained. The number of colonization (equal or higher than 15 CFU/plate) was present on 21 of the needleless connectors (20.0%). Coagulase-negative staphylococci was responsible for all the colonization. After disinfection for 15 s, no isolation exceeding 1 CFU/plate was present. Conclusion: Scrubbing for 15 s with 70% alcohol was found to be successful at elimination of colonization of the surface of needleless connector even in high microorganism counts.

scholarly journals Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults

2018 ◽  
Author(s):  
Eduardo López-Briz ◽  
Vicente Ruiz Garcia ◽  
Juan B Cabello ◽  
Sylvia Bort-Martí ◽  
Rafael Carbonell Sanchis ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Central Venous Catheters ◽  
Central Venous
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