Symptom experiences during chemotherapy treatment—With focus on nausea and vomiting

2006 ◽  
Vol 10 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Karin Bergkvist ◽  
Yvonne Wengström
2007 ◽  
Vol 5 (1) ◽  
pp. 12 ◽  
Author(s):  
_ _

Chemotherapy-induced nausea and vomiting (emesis) can significantly affect a patient's quality of life, leading to poor adherence with further chemotherapy treatment. In addition, nausea and vomiting can result in other serious complications and deterioration of the patient's status. These guidelines explore the prevention, treatment, and management of various types of emesis experienced by cancer patients, such as breakthrough, radiation-induced, and anticipatory. For the most recent version of the guidelines, please visit NCCN.org


2004 ◽  
Vol 2 (5) ◽  
pp. 470 ◽  

Chemotherapy-induced nausea and vomiting (emesis) can significantly affect a patient's quality of life, leading to poor adherence with further chemotherapy treatment. In addition, nausea and vomiting can result in metabolic imbalances, degeneration of self-care and functional ability, nutrient depletion, anorexia, decline of the patient's performance status and mental status, wound dehiscence, esophageal tears, and withdrawal from potentially useful or curative anticancer treatment. The incidence and severity of nausea and/or vomiting in patients receiving chemotherapy are affected by numerous factors, including (1) the specific chemotherapeutic agents used, (2) dosage, (3) the schedule and route of administration, and (4) individual patient variability. Approximately 70% to 80% of all cancer patients receiving chemotherapy experience emesis, and 10% to 44% experience anticipatory emesis. For the most recent version of the guidelines, please visit NCCN.org


2004 ◽  
Vol 2 (5) ◽  
pp. 501-508 ◽  
Author(s):  
Joseph A. Roscoe ◽  
Gary R. Morrow ◽  
Jane T. Hickok ◽  
Karen M. Mustian ◽  
Abhay R. Shelke

Although emesis can be considered a reflex to clear toxins from the body and involves mostly lower brain structures, nausea's purpose appears to be a warning signal to the individual to not engage in behaviors that he or she was doing at the time. As such, it involves the functioning of cognition and memory from higher developed neural structures. Given this, it should not be surprising that biobehavioral factors are important in predicting and controlling nausea. This article reviews the individual characteristics that are clinically useful in predicting which patients will have an increased probability of experiencing nausea or emesis during chemotherapy treatment, and also briefly review psychologic and biobehavioral treatments that can be useful in managing chemotherapy-related nausea.


2012 ◽  
Vol 35 (3) ◽  
pp. 203-210 ◽  
Author(s):  
Cheryl Rodgers ◽  
Deborah Kollar ◽  
Olga Taylor ◽  
Rosalind Bryant ◽  
Katie Crockett ◽  
...  

1984 ◽  
Vol 2 (10) ◽  
pp. 1170-1176 ◽  
Author(s):  
G R Morrow

Approximately one in four patients experiences nausea and/or vomiting in anticipation of a chemotherapy treatment by the time of their fourth treatment cycle. Anticipatory nausea and vomiting is a prevalent problem of clinical significance in the total management of chemotherapy side effects. While refractory to standard antiemetic treatment, anticipatory nausea and vomiting has been successfully treated with behavioral approaches such as systemic desensitization. The present study was designed to identify the characteristics of patients at high risk for developing anticipatory side effects. Early identification of cancer patients prone to developing anticipatory side effects could lead to preventive measures. One hundred seventy-six consecutive ambulatory patients with histologically confirmed cancer who were being treated at three geographically separate hospitals of the University of Rochester Cancer Center were studied at the time of their fourth chemotherapy treatment. Patients found to experience anticipatory nausea and vomiting were significantly more likely (P less than .001) to have four or more of the following characteristics than patients who did not report anticipatory side effects: (1) less than 50 years of age; (2) the experience of nausea and/or vomiting after their last chemotherapy treatment; (3) a description of nausea after the last treatment as "moderate, severe, or intolerable"; (4) a description of vomiting after the last treatment as "moderate, severe, or intolerable"; (5) the reporting of the side effect "warm or hot all over" after their last treatment; (6) a susceptibility to motion sickness; (7) the experience of "sweating after their last treatment"; (8) and the experience of "generalized weakness after their last chemotherapy treatment." Results support a view that anticipatory side effects are conditioned and point to practical interventions for their clinical control.


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